7,8,3,4'-tetrahydroxy-3'-methoxyflavone | 63807-91-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: 7,8,3,4'-tetrahydroxy-3'-methoxyflavone
• 英文别名: 3'-O-Methylmelanoxetin；3,7,8-trihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-chromen-4-one；3,7,8-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
• CAS: 63807-91-0
• 化学式: C₁₆H₁₂O₇
• 分子量: 316.267
• InChiKey: LATGNVTUYQHKQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  7,8,3,4'-tetrahydroxy-3'-methoxyflavone 、 乙酸酐 在 吡啶 作用下， 生成 3,7,8,4'-tetraacetoxy-3'-methoxyflavone
  参考文献：
  名称：

  A comparative study of the phenolic products in the heartwood of Acacia karroo from two different localities

  摘要：

  Known flavonoids were found in the heartwood of Acacia karroo. New natural products were isolated from the proposed subspecies montana. They are (2'S,3'R)-3,10-dihydroxy-9-O-(6'-hydroxy-7'-O-methyl-2'-hydroxy- methyldihydrobenzo furan-3-yl)dibenz-[b,d]-pyran-6-one and its 10-O-methyl analogue; 8-O-methylepiprosopin-4 beta-ol; 8-methoxyfustin; and 7,8,3,4'-tetrahydroxy-3'-methoxyflavone. Apart from the difference in substitution patterns of the compounds isolated from the two plant sources, the flavonoids from subspecies montana are O-methylated as opposed to none occurring in A. karroo.

  DOI：

  10.1016/0031-9422(95)00966-b

文献信息

• A comparative study of the phenolic products in the heartwood of Acacia karroo from two different localities
  作者：Elfranco Malan、Pricilla Swartz

  DOI：10.1016/0031-9422(95)00966-b

  日期：1995.7

  Known flavonoids were found in the heartwood of Acacia karroo. New natural products were isolated from the proposed subspecies montana. They are (2'S,3'R)-3,10-dihydroxy-9-O-(6'-hydroxy-7'-O-methyl-2'-hydroxy- methyldihydrobenzo furan-3-yl)dibenz-[b,d]-pyran-6-one and its 10-O-methyl analogue; 8-O-methylepiprosopin-4 beta-ol; 8-methoxyfustin; and 7,8,3,4'-tetrahydroxy-3'-methoxyflavone. Apart from the difference in substitution patterns of the compounds isolated from the two plant sources, the flavonoids from subspecies montana are O-methylated as opposed to none occurring in A. karroo.