2-Acetyl-5-ethylpyrazine | 43108-58-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-Acetyl-5-ethylpyrazine
• 英文别名: 1-(5-ethylpyrazin-2-yl)ethanone
• CAS: 43108-58-3
• 化学式: C₈H₁₀N₂O
• 分子量: 150.18
• InChiKey: MIDJYAWTZWQJGX-UHFFFAOYSA-N

物化性质

• 保留指数：
  1141.6

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  42.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Production of monoacylpyrazines
  申请人：PHILIP MORRIS INCORPORATED

  公开号：EP0076085A1

  公开（公告）日：1983-04-06

  This invention provides a process for preparing monoacylpyrazines which involves coreacting an aldehyde (R-CHO) and a pyrazine compound corresponding to the formula: where R1, R2 and R3 are substituents selected from hydrogen and alkyl groups, and R1 and R when taken together with connecting elements may form an alicyclic or aromatic structure, and R in the aldehyde compound is selected from aliphatic, alicyclic and aromatic groups under free radical conditions in a heterogeneous reaction medium consisting of an organic phase and an aqueous phase. The compounds prepared have the formula: where R, R', R2 and R3 are as previously defined, which is then recovered.

  本发明提供了一种制备单酰基吡嗪的工艺，该工艺包括在由有机相和水相组成的异相反应介质中，在自由基条件下，将醛（R-CHO）和式中所对应的吡嗪化合物进行共反应： 式中 R1、R2 和 R3 是选自氢和烷基的取代基，R1 和 R 与连接元素结合在一起时可形成脂环族或芳香族结构，醛化合物中的 R 选自脂肪族、脂环族和芳香族基团。 所制备的化合物具有式： 式中 R、R'、R2 和 R3 如前定义，然后将其回收。
• Smoking compositions containing a novel monoacylpyrazine flavorant
  申请人：Philip Morris Products Inc.

  公开号：EP0119718A1

  公开（公告）日：1984-09-26

  This invention provides novel monoacylpyrazine compounds having flavorant properties and smoking compositions which contain such compound as additives. In one of its embodiments, the monoacylpyrazine flavorant is 1-pyrazinyl-2,2-dimethyl-1-propanone: Under cigarette smoking conditions the above illustrated monoacylpyrazine additive flavors the mainstream smoke and enriches the aroma of the sidestream smoke.

  本发明提供了具有调味特性的新型单酰基吡嗪化合物，以及含有这种化合物作为添加剂的烟草组合物。 在其中一个实施例中，单酰基吡嗪调味剂是 1-吡嗪基-2,2-二甲基-1-丙酮： 在卷烟吸食条件下，上述单酰基吡嗪添加剂可为主流烟雾增香，并丰富侧流烟雾的香气。
• Smoking compositions containing acylpyrazine ether flavorants
  申请人：Philip Morris Products Inc.

  公开号：EP0148788A2

  公开（公告）日：1985-07-17

  57 The present invention provides a smoking composition which contains a novel type of acylpyrazine ether flavorant additive as exemplified by 1-(3-furfuryl- thio-2-pyrazinyl)-2-methyl-1-propanone: Further aspects of the invention provide; a process for the preparation of acylpyrazine ethers; novel haloacyl- pyrazine intermediates in the process; and a process for the preparation of haloacrylpyrazine intermediates.

  57 本发明提供了一种含有新型酰基吡嗪醚香料添加剂的烟用组合物，例如 1-(3-糠基-硫-2-吡嗪基)-2-甲基-1-丙酮： 本发明的其他方面提供了；一种制备酰基吡嗪醚的工艺；该工艺中的新型卤代酰基吡嗪中间体；以及一种制备卤代丙烯酰基吡嗪中间体的工艺。
• Ketones useful as precursors for organoleptic compounds
  申请人：Givaudan Roure (International) S.A.

  公开号：EP0983990A2

  公开（公告）日：2000-03-08

  The ketones of the formula I are useful for the delivery of organoleptic compounds, especially for flavours, fragrances and masking agents and antimicrobial compounds.

  式 I 中的酮类化合物可用于传递感官化合物，特别是香精、香料、掩蔽剂和抗菌化合物。
• US4481957A
  申请人：——

  公开号：US4481957A

  公开（公告）日：1984-11-13