2-Isopropylmaleate | 44976-69-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Isopropylmaleate
• 英文别名: 2-Propan-2-ylbut-2-enedioic acid
• CAS: 44976-69-4
• 化学式: C₇H₁₀O₄
• 分子量: 158.154
• InChiKey: NJMGRJLQRLFQQX-UHFFFAOYSA-N

物化性质

• 熔点：
  54 °C
• 沸点：
  331.5±25.0 °C(Predicted)
• 密度：
  1.1312 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-Isopropylmaleate 在 溶剂黄146 、 三氟乙酸酐 作用下， 反应 1.5h， 生成 2,5-二氢-3-异丙基-2,5-二氧代-1H-吡咯-1-丙酸
  参考文献：
  名称：

  Synthesis of natural maleimides farinomaleins C–E and evaluation of their antifungal activity

  摘要：

  A practical and convenient synthesis of naturally occurring farinomaleins C-E was achieved starting from readily available ethyl 3-methyl-2-oxobutyrate and triethyl phosphonoacetate. The key steps of the sequence included a Horner-Wadsworth-Emmons condensation to obtain the precursor farinomalein A and coupling with suitable alcohols to install the chain. The synthesis of farinomalein D has been achieved starting from (R)-isopropylideneglycerol on the basis of which the S configuration was assigned to the natural compound. The antifungal activity of the synthesized compounds was evaluated against Cladosporium cladosporioides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.023
• 作为产物：
  描述：

  3-甲基-2-氧代丁酰乙酯 在 sodium hydride 、 lithium hydroxide 作用下， 以 四氢呋喃 、 mineral oil 为溶剂， 反应 9.0h， 生成 2-Isopropylmaleate
  参考文献：
  名称：

  Synthesis of natural maleimides farinomaleins C–E and evaluation of their antifungal activity

  摘要：

  A practical and convenient synthesis of naturally occurring farinomaleins C-E was achieved starting from readily available ethyl 3-methyl-2-oxobutyrate and triethyl phosphonoacetate. The key steps of the sequence included a Horner-Wadsworth-Emmons condensation to obtain the precursor farinomalein A and coupling with suitable alcohols to install the chain. The synthesis of farinomalein D has been achieved starting from (R)-isopropylideneglycerol on the basis of which the S configuration was assigned to the natural compound. The antifungal activity of the synthesized compounds was evaluated against Cladosporium cladosporioides. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.05.023

文献信息

• Aspartates containing ketimine-groups and their use in coating compositions
  申请人：Bayer MaterialScience LLC

  公开号：EP1518852A1

  公开（公告）日：2005-03-30

  The present invention relates to novel aspartates, their method of production and the use of these aspartates as reactive components for polyisocyanates in two-component polyurethane coating compositions and for preparing polyurethane prepolymers. The aspartaes are prepared by first reacting a di- or polyamine with an unsaturated ester and then reacting the resultant product with a ketone.

  本发明涉及新型天冬氨酸盐，其生产方法以及将这些天冬氨酸盐作为双组分聚氨酯涂料组合物中聚异氰酸酯的反应组分和制备聚氨酯预聚物的用途。这些天冬氨酸盐是通过首先将二元或多元胺与不饱和酯反应，然后将所得产物与酮反应制备而成的。
• COPOLYMERS AND COMPOSITIONS WITH ANTI-ADHESIVE AND ANTIMICROBIAL PROPERTIES
  申请人：BASF SE

  公开号：US20160235062A1

  公开（公告）日：2016-08-18

  The invention relates to a copolymer exhibiting both antimicrobial and anti-adhesive properties as well as to a hydrogel. Said hydrogel is obtained from the inventive copolymer and a substrate. Another part of the invention is a process for making the hydrogel, as well as different uses of the inventive copolymer as well as of the hydrogel.

  该发明涉及一种既具有抗菌和抗粘附性能的共聚物，又涉及一种水凝胶。所述水凝胶是由该创新共聚物和基质制得的。该发明的另一部分是制备水凝胶的方法，以及该创新共聚物和水凝胶的不同用途。
• [EN] ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION<br/>[FR] ASPARTATES UTILISES COMME CONSTITUANTS DANS DES COMPOSITIONS DE REVETEMENT, ET LEUR PREPARATION
  申请人：BAYER MATERIALSCIENCE LLC

  公开号：WO2005073188A1

  公开（公告）日：2005-08-11

  The present invention relates to novel aspartates, their method of production and the use of these aspartates as reactive components for polyisocyanates in two-component polyurethane coating compositions and for preparing polyurethane prepolymers. The aspartates are prepared by first reacting a di- or polyamine with an unsaturated ester and then reacting the resultant product with a maleimide.

  本发明涉及新颖的天冬氨酸、其制备方法以及将这些天冬氨酸作为双组分聚氨酯涂料组成部分的聚异氰酸酯反应组分和制备聚氨酯预聚体。这些天冬氨酸是通过首先将二元或多元胺与不饱和酯反应，然后将产物与马来酰亚胺反应制备而成。
• [EN] MIXED CATALYTIC COMPOSITION<br/>[FR] COMPOSITION CATALYTIQUE MIXTE
  申请人：CROMPTON GMBH

  公开号：WO2004050597A1

  公开（公告）日：2004-06-17

  The present invention relates to catalytic compositions for esterification, transesterification and polycondensation reactions, a process for the catalysis of said reactions employing such catalytic compositions and polyesters or resins obtainable by this process.

  本发明涉及用于酯化、转酯化和聚合反应的催化组合物，以及使用这种催化组合物催化该反应的过程和可由该过程获得的聚酯或树脂。
• Photoresponsive fragrances
  申请人：Stowell H.B. Michael

  公开号：US20050020459A1

  公开（公告）日：2005-01-27

  This invention provides fragrance compositions comprising a carrier solution used for cleaning purposes or for topical administration and nonfragrant photoresponsive agents that are capable of undergoing intramolecular photorearrangements to release a fragrance. The photoresponsive fragrance composition may comprise the prephotorearrangement first fragrance agent, the photorearranged and released fragrance agent, a combination of the first and second agents, or any of the above in combination with a known fragrance agent.

  本发明提供了一种香气组合物，包括用于清洁或局部给药的载体溶液和非芳香光响应剂，该光响应剂能够发生分子内光重排反应以释放香气。该光响应香气组合物可以包括预光重排的第一香料剂、光重排释放的香料剂、第一和第二剂的组合，或上述任何一种与已知香料剂的组合。