almazole B

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: almazole B
• 英文别名: (2-Aminophenyl)-[2-[1-(dimethylamino)-2-phenylethyl]-1,3-oxazol-5-yl]methanone
• 化学式: C₂₀H₂₁N₃O₂
• 分子量: 335.406
• InChiKey: NRJOOMIJSJOZAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  72.4
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  almazole A 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 0.5h， 以74%的产率得到almazole B
  参考文献：
  名称：

  Almazole A and almazole B, unusual marine alkaloids of an unidentified red seaweed of the family delesseriaceae from the coasts of Senegal

  摘要：

  Almazole A 1 -slowly equilibrating in solution between the major Z 1a and the minor E 1b forms- and almazole B 2, unusual marine alkaloids for embodying a 2,5-disubstituted oxazole ring, were isolated from an unidentified red seaweed of the family Delesseriaceae from the coasts of Senegal.

  DOI：

  10.1016/s0040-4039(00)76979-6

文献信息

• Almazole A and almazole B, unusual marine alkaloids of an unidentified red seaweed of the family delesseriaceae from the coasts of Senegal
  作者：Ibrahima N'Diaye、Graziano Guella、Giuseppe Chiasera、Ines Mancini、Francesco Pietra

  DOI：10.1016/s0040-4039(00)76979-6

  日期：1994.7

  Almazole A 1 -slowly equilibrating in solution between the major Z 1a and the minor E 1b forms- and almazole B 2, unusual marine alkaloids for embodying a 2,5-disubstituted oxazole ring, were isolated from an unidentified red seaweed of the family Delesseriaceae from the coasts of Senegal.