N-(5-acetamido-4,6-dihydroxy-2-methyloxan-3-yl)acetamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-(5-acetamido-4,6-dihydroxy-2-methyloxan-3-yl)acetamide
• 化学式: C₁₀H₁₈N₂O₅
• 分子量: 246.26
• InChiKey: NRXWTRNYICXMBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  108
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• CELL-BASED PRODUCTION OF NANULOSONATES
  申请人：Boddy Christopher N.

  公开号：US20130196381A1

  公开（公告）日：2013-08-01

  The present invention relates to the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-α-D-glucopyranose. Methods for producing the sugars are also provided.
• BIOCONJUGATE VACCINES MADE IN PROKARYOTIC CELLS
  申请人：Faridmoayer Amirreza

  公开号：US20140336366A1

  公开（公告）日：2014-11-13

  Provided herein are prokaryotic cells capable of producing bioconjugates comprising glycosylated proteins. Also provided herein are compositions comprising such bioconjugates and/or comprising the saccharide moieties of such bioconjugates, as well as methods of vaccinating subjects using such compositions.
• CELL-BASED PRODUCTION OF NONULOSONATES
  申请人：National Research Council of Canada

  公开号：US20140356912A1

  公开（公告）日：2014-12-04

  The present invention relates to the the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-□-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-□-D-glucopyranose. Methods for producing the sugars are also provided.
• ANTIGENIC COMBINATIONS AGAINST FRANCISELLA BACTERIA AND RELATED NANOLIPOPROTEIN PARTICLES, COMPOSITIONS, METHODS AND SYSTEMS
  申请人：LAWRENCE LIVERMORE NATIONAL SECURITY, LLC

  公开号：US20200108133A1

  公开（公告）日：2020-04-09

  Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
• US8841099B2
  申请人：——

  公开号：US8841099B2

  公开（公告）日：2014-09-23