Tricyclo[6.2.0.03,6]deca-1(8),2,6-triene-4,10-dione

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Tricyclo[6.2.0.03,6]deca-1(8),2,6-triene-4,10-dione
• 化学式: C₁₀H₆O₂
• 分子量: 158.156
• InChiKey: RYTQZOUDUSLAPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  在 aluminum oxide 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成 Tricyclo[6.2.0.03,6]deca-1(8),2,6-triene-4,10-dione
  参考文献：
  名称：

  Synthetic Approach to Benzocyclobutenones Using Visible Light and a Phosphonate Auxiliary

  摘要：

  Reported herein is a two-step procedure to synthesize benzocyclobutenones from (o-alkylbenzoyl)-phosphonates. It consists of a visible-light-driven cyclization reaction forming phosphonate-substituted benzocyclobutenols and subsequent elimination reaction of the H-phosphonate, which assumes a key role as the recyclable auxiliary. A wide variety of functionalized benzocyclobutenones, which include those difficult to synthesize by conventional methods, are efficiently synthesized.

  DOI：

  10.1021/acs.orglett.8b00160