3,4-Di-O-Caffeoylquinic acid

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-Di-O-Caffeoylquinic acid
• 英文别名: 3,4-bis[3-(3,4-dihydroxyphenyl)prop-2-enoyloxy]-1,5-dihydroxycyclohexane-1-carboxylic acid
• 化学式: C₂₅H₂₄O₁₂
• 分子量: 516.4
• InChiKey: UFCLZKMFXSILNL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  37
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  211
• 氢给体数：
  7
• 氢受体数：
  12

文献信息

• EFFECTS OF A DECAFFEINATED GREEN COFFEE EXTRACT ON BODY WEIGHT CONTROL BY REGULATION OF GLUCOSE METABOLISM
  申请人：IBARRA Alvin

  公开号：US20110223281A1

  公开（公告）日：2011-09-15

  A method of controlling body weight in humans by administering an amount of decaffeinated green coffee extract effective to treat a subject. A preferred green coffee extract contains a ratio of 4-caffeoylquinic acid (4-CQA) to total chlorogenic acids (tCGA) (5-CQA/tCGA) of from about 0.1 to about 0.2. More preferably, the green coffee extract comprises from about 6% to about 8% of 4-caffeoylquinic acid and has a total chlorgenic acid concentration that exceeds about 45%. A preferred method of administration consists of administering the green coffee extracts is a dosage of about 200 mg twice a day prior to meals on an empty stomach.
• US9358264B2
  申请人：——

  公开号：US9358264B2

  公开（公告）日：2016-06-07