L-Sorbitol permethyl

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: L-Sorbitol permethyl
• 英文别名: 1,2,3,4,5,6-hexamethoxyhexane
• 化学式: C₁₂H₂₆O₆
• 分子量: 266.33
• InChiKey: UJQZVTQJKNAPOQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  18
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  55.4
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Levulinic acid ester derivatives as reactive plasticizers and coalescent solvents
  申请人：Bloom Paul D.

  公开号：US20100216915A1

  公开（公告）日：2010-08-26

  The present invention is directed to ester derivatives of levulinic acid that are useful as plasticizers and/or coalescent solvents in polymer compositions, compositions comprising the ester derivatives, methods of making the derivatives and the compositions, and the use of the derivatives as additives in polymer compositions.

  本发明涉及丙酮酸酯衍生物，其可用作聚合物组合物中的增塑剂和/或凝聚溶剂，包含该酯衍生物的组合物，制备该衍生物和组合物的方法以及将该衍生物用作聚合物组合物中的添加剂。
• Preparation of Polymer Conjugates of Therapeutic, Agricultural, and Food Additive Compounds
  申请人：Konradi W. Andrei

  公开号：US20080031848A1

  公开（公告）日：2008-02-07

  This invention provides an improved synthesis of polymer conjugates of formula (I), of agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobu” or related reaction conditions.
• METHODS FOR STRUCTURAL ANALYSIS OF GLYCANS
  申请人：Lapadula Anthony

  公开号：US20110137570A1

  公开（公告）日：2011-06-09

  The invention relates to methods useful for the structural analysis of glycans. Methods are disclosed for sequencing glycans using stepwise disassembly processes by analysis of the fragments produced therein. Methods are additionally provided for identifying MS n disassembly pathways that are inconsistent with a set of expected structures, and which therefore may indicate the presence of alternative isomeric structures. A method for interactive spectra annotation is also provided.
• MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR
  申请人：XIAMEN SINOPEG BIOTECH CO., LTD.

  公开号：US20170312363A1

  公开（公告）日：2017-11-02

  Disclosed are a multifunctionalized polyethylene glycol derivative and a preparation method therefor. The derivative has an H-shaped structure as represented by formula (1) and comprises one linear core LPEG and four PEG branch chains, where n 1 , n 2 , n 3 , and n 4 respectively are the degrees of polymerization of the branch chains, U 1 and U 2 are trivalent branching groups connecting the core LPEG to two of the PEG branch chains, F 1 and F 2 contain a functional group or a protected form R 01 thereof and may or may not contain a branched group G, correspondingly, the number of R 01 is one or more, F 1 and F 2 are either identical or different, any one linking group in the molecule or any linking group formed with an adjacent heteroatom group can either remain stable or be degraded, and any one PEG segment in the molecule is discretely polydispersed or monodispersed. The multifunctional polyethylene glycol is flexible and diverse in terms of branch structures and the lengths of branching arms, has various parameters and performance indicators that are adjustable and easy to control, and has a broad applicability.
• Hydrogel-Linked IL-1ra Prodrug
  申请人：ASCENDIS PHARMA OSTEOARTHRITIS DIVISION A/S

  公开号：US20180042996A1

  公开（公告）日：2018-02-15

  The present invention relates to a hydrogel-linked IL-Ira prodrug or pharmaceutically acceptable salt thereof. It further relates to a pharmaceutical composition comprising said hydrogel-linked IL-Ira prodrug, its use as medicament for the treatment of a IL-1 mediated disease, ways of application of such hydrogel-linked IL-Ira prodrugs or pharmaceutical compositions, and containers comprising the hydrogel-linked IL-Ira prodrugs or pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising said hydrogel-linked IL-Ira prodrug or pharmaceutically acceptable salt thereof.