3,4,5-Trihydroxy-2-methoxyhexanal

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4,5-Trihydroxy-2-methoxyhexanal
• 化学式: C₇H₁₄O₅
• 分子量: 178.18
• InChiKey: VCUILRLOJMHSMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  87
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] AZIRIDINE SPINOSYN DERIVATIVES AND METHODS OF MAKING<br/>[FR] DÉRIVÉS D'AZIRIDINE SPINOSYNE ET LEURS PROCÉDÉS DE FABRICATION
  申请人：AGRIMETIS LLC

  公开号：WO2018132288A1

  公开（公告）日：2018-07-19

  Compositions including derivatives of spinosyns of the following formulae and methods for the production of derivatives of spinosyns are provided. The spinosyn derivatives described herein include those functionalized on the C-5,6 double bond to provide an aziridine ring system. The method produces spinosyn derivatives that exhibit activity towards insects, arachnids, and nematodes and are useful in the agricultural and animal health markets.

  提供了包括以下公式的自旋菌素衍生物的组合物，以及用于生产自旋菌素衍生物的方法。本文描述的自旋菌素衍生物包括在C-5,6双键上官能化以提供环氮丙烷环系统的衍生物。该方法生产出对昆虫、蜘蛛和线虫具有活性的自旋菌素衍生物，并在农业和动物健康市场中有用。
• Method for producing meso-galactaric acid by contacting a fungal cell with a biomaterial having galacturonic acid
  申请人：TEKNOLOGIAN TUTKIMUSKESKUS VTT OY

  公开号：US10982239B2

  公开（公告）日：2021-04-20

  The present invention relates to a field of genetically modified fungal cells and converting galacturonic acid to meso-galactaric acid, more precisely to a method of producing meso-galactaric acid. The invention further relates to recombinant fungal cells having a specific combination of modifications including but not limited to expression of uronate dehydrogenase enzyme, reduced D-galacturonic acid reductase activity, and furthermore reduced meso-galactaric acid catabolism, as well as uses and methods related thereto.

  本发明涉及转基因真菌细胞和将半乳糖醛酸转化为中半乳糖醛酸的领域，更确切地说，涉及一种生产中半乳糖醛酸的方法。本发明还涉及具有特定修饰组合的重组真菌细胞，这些修饰组合包括但不限于表达尿酸脱氢酶、降低 D-半乳糖醛酸还原酶活性、进一步降低中半乳糖醛酸分解代谢，以及与之相关的用途和方法。
• IMPROVED MESO-GALACTARIC ACID PRODUCTION FROM GALACTURONIC ACID WITH GENETICALLY MODIFIED FUNGAL CELLS
  申请人：Teknologian Tutkimuskeskus VTT OY

  公开号：EP3458578A1

  公开（公告）日：2019-03-27
• AZIRIDINE SPINOSYN DERIVATIVES AND METHODS OF MAKING
  申请人：Agrimetis, LLC

  公开号：EP3568399A1

  公开（公告）日：2019-11-20
• REGULATED BIOCIRCUIT SYSTEMS
  申请人：Obsidian Therapeutics, Inc.

  公开号：US20190192691A1

  公开（公告）日：2019-06-27

  The present invention provides regulatable biocircuit systems. Such systems provide modular and tunable protein expression systems in support of the discovery and development of therapeutic modalities.