Methyl 2,3,6-tri-o-benzoylhexopyranoside | 6344-46-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl 2,3,6-tri-o-benzoylhexopyranoside
• 英文别名: (4,5-dibenzoyloxy-3-hydroxy-6-methoxyoxan-2-yl)methyl benzoate
• CAS: 6344-46-3
• 化学式: C₂₈H₂₆O₉
• 分子量: 506.5
• InChiKey: WXFFEILSURAFKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  37
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  118
• 氢给体数：
  1
• 氢受体数：
  9

文献信息

• NOVEL FLUOROGLYCOSIDE DERIVATIVES OF PYRAZOLES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF
  申请人：BRUMMERHOP Harm

  公开号：US20070197623A1

  公开（公告）日：2007-08-23

  The invention relates to substituted fluoroglycoside derivatives of pyrazoles of formula (I) as further defined in the specification, to the physiologically compatible salts thereof, to a method for their production, and to their use as antidiabetics.

  本发明涉及一种代替氟基的吡唑烷基糖苷衍生物，其化学式为（I），在规范中进一步定义，其生理兼容盐的制备方法，以及它们作为抗糖尿病药物的用途。
• NOVEL AROMATIC FLUOROGLYCOSIDE DERIVATIVES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF
  申请人：FRICK Wendelin

  公开号：US20080108580A1

  公开（公告）日：2008-05-08

  Novel aromatic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof. The invention relates to substituted aromatic fluoroglycoside derivatives of the formula I in which the radicals have the stated meanings, and their physiologically tolerated salts and process for their preparation. The compounds are suitable for example as antidiabetics.

  小说芳香族氟代糖苷衍生物，含有这些化合物的药物，以及它们的使用。本发明涉及式I的取代芳香族氟代糖苷衍生物，其中基团具有所述的含义，以及其生理上耐受的盐和制备过程。这些化合物例如适用于抗糖尿病药物。
• USE OF COMPOUNDS WITH SGLT-1/SGLT-2 INHIBITOR ACTIVITY FOR PRODUCING MEDICAMENTS FOR TREATMENT OF BONE DISEASE
  申请人：Kissner Thomas

  公开号：US20120270819A1

  公开（公告）日：2012-10-25

  Use of compounds with SGLT-1/SGLT-2 inhibitor activity for producing medicaments for treatment of bone diseases The invention relates to the use of compounds with SGLT-1/SGLT-2 inhibitor activity for producing medicaments for treatment of bone diseases like osteoporosis. Preferred is the use of compounds of the formula I in which the radicals have the stated meanings.

  使用具有SGLT-1/SGLT-2抑制剂活性的化合物制备用于治疗骨疾病的药物。本发明涉及使用具有SGLT-1/SGLT-2抑制剂活性的化合物制备用于治疗骨疾病，如骨质疏松症的药物。首选使用式I中基团具有所述含义的化合物。
• Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
  申请人：FRICK Wendelin

  公开号：US20100261664A1

  公开（公告）日：2010-10-14

  Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof The invention relates to substituted heterocyclic fluoroglycoside derivatives of the formula I in which the radicals have the stated meanings, and their physiologically tolerated salts and processes for their preparation. The compounds are suitable for example as antidiabetics.

  新型杂环氟代糖苷衍生物、含有这些化合物的药物以及它们的使用本发明涉及公式I的取代的杂环氟代糖苷衍生物，其中基团具有所述的含义，以及它们的生理上耐受的盐和制备它们的过程。这些化合物例如适用于抗糖尿病。
• METHOD FOR PRODUCING 4-DEOXY-4-FLUORO-D-GLUCOSE DERIVATIVE
  申请人：Central Glass Company, Limited

  公开号：EP2216337A1

  公开（公告）日：2010-08-11

  There is disclosed a method for producing a 4-deoxy-4-fluoro-D-glucose derivative by reacting a D-galactose derivative with either sulfuryl fluoride (SO2F2), trifluoromethanesulfonyl fluoride (CF3SO2F) or perfluorobutanesulfonyl fluoride (C4F9SO2F) in the presence of an organic base or in the presence of an organic base and a salt or complex of an organic base and hydrogen fluoride.

  本发明公开了一种生产 4-脱氧-4-氟-D-葡萄糖衍生物的方法，该方法是将 D-半乳糖衍生物与硫酰氟（SO2F2）、三氟甲基磺酰氟（CF3SO2F）或全氟丁基磺酰氟（C4F9SO2F）在有机碱存在下或在有机碱和有机碱与氟化氢的盐或络合物存在下反应。