L-sorbosone pyranose form

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: L-sorbosone pyranose form
• 英文别名: 2,3,4,5-tetrahydroxyoxane-2-carbaldehyde
• 化学式: C₆H₁₀O₆
• 分子量: 178.14
• InChiKey: YOWZFXGYLFJKGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Glycated CD59 peptides, their preparation, and uses thereof
  申请人：President and Fellows of Harvard College

  公开号：US11161910B2

  公开（公告）日：2021-11-02

  The present invention provides glycated Amadori products of the CD59 peptide and fragments thereof to be used as tools and among methods for the diagnosis and prognosis of pre-diabetes and diabetes. Certain aspects of the invention include glycated Amadori products of CD59 and fragments thereof to be used for the generation of antibodies and antibody fragments. Still other aspects of the invention include methodologies for the preparation of glycated Amadori products of CD59, fragments thereof, the inventive antibodies, and antibody fragments.

  本发明提供了CD59肽的糖化Amadori产物及其片段，可用作诊断糖尿病前期和糖尿病的工具和方法。本发明的某些方面包括用于生成抗体和抗体片段的 CD59 的糖化阿莫多利产物及其片段。本发明的其他方面还包括制备CD59的糖化阿莫多利产物、其片段、本发明抗体和抗体片段的方法。
• GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF
  申请人：Halperin Jose A

  公开号：US20130224211A1

  公开（公告）日：2013-08-29

  The present invention provides glycated Amadori products of the CD59 peptide and fragments thereof to be used as tools and among methods for the diagnosis and prognosis of pre-diabetes and diabetes. Certain aspects of the invention include glycated Amadori products of CD59 and fragments thereof to be used for the generation of antibodies and antibody fragments. Still other aspects of the invention include methodologies for the preparation of glycated Amadori products of CD59, fragments thereof, the inventive antibodies, and antibody fragments.
• [EN] GLYCATED CD59 PEPTIDES, THEIR PREPARATION, AND USES THEREOF<br/>[FR] PEPTIDES CD59 GLYQUÉS, LEUR PRÉPARATION ET LEURS UTILISATIONS
  申请人：HARVARD COLLEGE

  公开号：WO2012027555A2

  公开（公告）日：2012-03-01

  The present invention provides glycated Amadori products of the CD59 peptide and fragments thereof to be used as tools and among methods for the diagnosis and prognosis of pre-diabetes and diabetes. Certain aspects of the invention include glycated Amadori products of CD59 and fragments thereof to be used for the generation of antibodies and antibody fragments. Still other aspects of the invention include methodologies for the preparation of glycated Amadori products of CD59, fragments thereof, the inventive antibodies, and antibody fragments.