Methyl hexofuranoside | 56654-39-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methyl hexofuranoside
• 英文别名: methyl-hexafuranoside；alpha-d-Mannofuranoside, methyl；2-(1,2-dihydroxyethyl)-5-methoxyoxolane-3,4-diol
• CAS: 56654-39-8；4097-91-0
• 化学式: C₇H₁₄O₆
• 分子量: 194.185
• InChiKey: ZSQBOIUCEISYSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.1
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• NKT cell-activating agents containing alpha-glycosylceramides
  申请人：Kyowa Hakko Kirin Co., Ltd.

  公开号：EP1520583B1

  公开（公告）日：2009-01-28
• Nasal Vaccine
  申请人：Seino Ken-ichiro

  公开号：US20090214596A1

  公开（公告）日：2009-08-27

  The present invention provides a nasal vaccine capable of intranasally inducing an effective immunity reaction. Specifically, the invention provides a nasal vaccine containing a compound having an NKT cell-activating action, particularly a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a compound represented by the formula (II): wherein each symbol is as defined in the specification, and an immunogen in an amount effective for stimulating an immune response.
• COMPOSITIONS COMPRISING A B SUBUNIT OF SHIGA TOXIN AND A MEANS STIMULATING NKT CELLS
  申请人：Tartour Eric

  公开号：US20100196417A1

  公开（公告）日：2010-08-05

  The present invention relates to a composition comprising a) a B subunit of Shiga toxin or a functional equivalent thereof which is able to bind the Gb3 receptor, complexed with an antigen and b) at least one ligand of CDI capable of stimulating NK T cells; and to a pharmaceutical composition and a medicament comprising said composition.