2-phenyl-1H-pyrimidine-4,6-dione | 63447-35-8

• 物质功能分类: 医药中间体 - 嘧啶类化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-phenyl-1H-pyrimidine-4,6-dione
• 英文别名: 2-Phenyl-1H-pyrimidin-4,6-dion；2-Phenyl-1h-pyrimidine-4,6-dione
• CAS: 63447-35-8
• 化学式: C₁₀H₈N₂O₂
• 分子量: 188.186
• InChiKey: BXXMMIMXZYATIO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  58.5
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2933599090

反应信息

• 作为反应物：
  描述：

  2-phenyl-1H-pyrimidine-4,6-dione 在 硝酸 作用下， 生成 4,6-二氯-5-硝基-2-苯基嘧啶
  参考文献：
  名称：

  Consensus strategy in suspected pulmonary embolism

  摘要：

  DOI：

  10.1093/qjmed/93.9.639
• 作为产物：
  描述：

  苯甲脒 、 丙二酸二乙酯 生成 2-phenyl-1H-pyrimidine-4,6-dione
  参考文献：
  名称：

  Consensus strategy in suspected pulmonary embolism

  摘要：

  DOI：

  10.1093/qjmed/93.9.639

文献信息

• 4-Amino-2-phenyl-6-thiopryimidines
  申请人：American Home Products Corporation

  公开号：US03940395A1

  公开（公告）日：1976-02-24

  The invention is directed to 4-amino-2-phenyl-6-thiopyrimidine compounds having the formula ##SPC1## Where R.sup.1 -R.sup.3 are as defined in the specification. The compounds have pharmacodynamic activity as central nervous system depressants. That is, they produce a calming effect in the host.

  本发明涉及具有以下式的4-氨基-2-苯基-6-硫代嘧啶化合物：##SPC1## 其中R1-R3如规范中所定义。该化合物具有作为中枢神经系统抑制剂的药效活性。也就是说，它们在宿主体内产生镇静效果。
• Process for production of vinyl chloride polymer
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP0172427A2

  公开（公告）日：1986-02-26

  This process is a process for production of a vinyl chloride polymer by suspension polymerization or emulsion polymerization of vinyl chloride monomer or a mixture of vinyl chloride monomer with a vinyl monomer copolymerizable with said vinyl chloride monomer in an aqueous medium, characterized in that the polymerization is carried out in a polymerizer, the inner wall surface and portions of the auxiliary equipment thereof which may come into contact with the monomer during polymerization being previously coated with a scaling preventive comprising at least one selected from dyes, pigments and aromatic or heterocyclic compounds having at least 5 conjugated π bonds, while controlling the chloride ion concentration in the reaction mixture to not higher than 100 ppm. According to said process, scaling onto the inner wall surface of a polymerizer, etc. during polymerization can be prevented effectively and surely.

  该工艺是通过氯乙烯单体或氯乙烯单体与可与所述氯乙烯单体共聚的乙烯基单体混合物在水介质中进行悬浮聚合或乳液聚合来生产氯乙烯聚合物的工艺，其特征在于聚合是在聚合器中进行的、内壁表面及其辅助设备中可能在聚合过程中与单体接触的部分事先涂上一层防垢剂，该防垢剂至少包括一种选自染料、颜料和至少有 5 个共轭 π 键的芳香族或杂环化合物的防垢剂，同时控制反应混合物中的氯离子浓度不高于 100 ppm。根据上述工艺，可有效、可靠地防止聚合过程中聚合器等内壁表面结垢。
• Dox; Yoder, Journal of the American Chemical Society, 1922, vol. 44, p. 364
  作者：Dox、Yoder

  DOI：——

  日期：——
• DE520854
  申请人：——

  公开号：——

  公开（公告）日：——
• The Joint Influence of Agricultural and Nonfarm Factors on Real Estate Values: An Application to the Mid‐Atlantic Region
  作者：Ian W. Hardie、Tulika A. Narayan、Bruce L. Gardner

  DOI：10.1111/0002-9092.00141

  日期：2001.2

  AbstractCounty level farmland and residential housing values are estimated for the Mid‐Atlantic region as a function of farm returns, developed land values, household incomes, population densities, and location. Results are based on the hypothesis that farmland owners anticipate land development and that nonfarm factors are important determinants of farmland prices. Response of farmland prices to change in farm returns is found to be inelastic and relatively uniform in rural and urban counties. Response to nonfarm factors is found to be more elastic and substantially greater in rural counties.