(2S)-2-[5-(dithiolan-3-yl)pentanoylamino]-3-(1H-indol-3-yl)propanoic acid | 1101-98-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2S)-2-[5-(dithiolan-3-yl)pentanoylamino]-3-(1H-indol-3-yl)propanoic acid
• CAS: 1101-98-0
• 化学式: C₁₉H₂₄N₂O₃S₂
• 分子量: 392.543
• InChiKey: BIFIMWQIZPGFDP-JRZJBTRGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  133
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  L-色氨酸 、 DL-α-硫辛酸-NHS 在 HEPES buffer 作用下， 以 丙酮 为溶剂， 反应 24.0h， 以64%的产率得到(2S)-2-[5-(dithiolan-3-yl)pentanoylamino]-3-(1H-indol-3-yl)propanoic acid
  参考文献：
  名称：

  Photorelease of Carboxylic Acids Mediated by Visible-Light-Absorbing Gold-Nanoparticles

  摘要：

  Visible-light-absorbing citrate-stabilized gold nanoparticles and tryptophan-dithiane-conjugate-stabilized gold nanoparticles have been used to mediate electron transfer between dithiothreitol (DTT), a good electron donor, and an N-methylpicolinium ester in aqueous solution. Quantitative yield of the free carboxylate has been obtained with quantum yields of release, 4),1, ranging from 0.5 to 4.5.

  DOI：

  10.1021/ol702813w

文献信息

• Photorelease of Carboxylic Acids Mediated by Visible-Light-Absorbing Gold-Nanoparticles
  作者：J. Brian Borak、Susana López-Sola、Daniel E. Falvey

  DOI：10.1021/ol702813w

  日期：2008.2.1

  Visible-light-absorbing citrate-stabilized gold nanoparticles and tryptophan-dithiane-conjugate-stabilized gold nanoparticles have been used to mediate electron transfer between dithiothreitol (DTT), a good electron donor, and an N-methylpicolinium ester in aqueous solution. Quantitative yield of the free carboxylate has been obtained with quantum yields of release, 4),1, ranging from 0.5 to 4.5.