(2Z)-2-Hexyldec-2-enal | 61960-01-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (2Z)-2-Hexyldec-2-enal
• 英文别名: (Z)-2-hexyldec-2-enal；2-hexyldec-2-enal
• CAS: 61960-01-8
• 化学式: C₁₆H₃₀O
• 分子量: 238.414
• InChiKey: RSBRHLFCWKXUSQ-PEZBUJJGSA-N

物化性质

• 沸点：
  331.8±11.0 °C(Predicted)
• 密度：
  0.841±0.06 g/cm3(Predicted)
• 保留指数：
  1752

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  17
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  正辛醛 在 copper(II) bis(trifluoromethanesulfonate) 丙酮酸甲酯 作用下， 以 二氯甲烷 为溶剂， 反应 40.0h， 以70%的产率得到(2Z)-2-Hexyldec-2-enal
  参考文献：
  名称：

  Dujardin; Leconte; Bénard, Synlett, 2001, # 1, p. 147 - 149

  摘要：

  DOI：

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• ALKYL H-PHOSPHONATES OF N,N'-DIALKYLIMIDAZOLIUMS AND OF QUATERNARY AMMONIUMS AND USES THEREOF
  申请人：Nguyen Hoang-Phuong

  公开号：US20100121075A1

  公开（公告）日：2010-05-13

  The application relates to the use of a salt associating an ammonium cation with an alkyl H-phosphonate anion of the following formula (I) in which R is a hydrocarbon radical, the pointed bond can be present or not, the radical R 3 being then present or absent, as an ionic liquid. The ammonium cation is preferably an imidazolium cation. This ionic liquid is particularly useful in the field of green chemistry as a substitute for organic solvents. The application also relates to a method for preparing such a salt by the direct dealkylation of the corresponding dialkylphosphite by the appropriate nitrated base, in one step and without any solvent. The application also relates to a method for preparing mixed methylated phosphites.

  该申请涉及使用盐将氨基阳离子与以下式(I)中的烷基H-膦酸盐结合，其中R是一个碳氢基团，指示的键可以存在也可以不存在，基团R3则存在或不存在，作为离子液体。氨基阳离子最好是咪唑阳离子。这种离子液体在绿色化学领域中特别有用，可作为有机溶剂的替代品。该申请还涉及通过适当的硝基碱直接脱烷基化相应的二烷基膦酸酯来制备这种盐的方法，一步完成且无需任何溶剂。该申请还涉及制备混合甲基化膦酸酯的方法。
• Synthesis and Sensorial Properties of 2-Alkylalk-2-enals and 3-(Acetylthio)-2-alkyl Alkanals
  作者：Fabien Robert、Julien Héritier、Joelle Quiquerez、Hervé Simian、Imre Blank

  DOI：10.1021/jf0498968

  日期：2004.6.1

  characterized in terms of GC, MS, and NMR data. The sensory properties of the odorants, such as odor quality and odor detection threshold value, were determined with a trained panel. Structure-activity relationships are discussed, suggesting that the 1,3-oxygen-sulfur functionality, required for the "olfactophore" of tropical/vegetable notes, can further be extended to the acetylthio derivatives.

  通过在碱性条件下将硫代乙酸迈克尔加成到α，β-不饱和2-烷基取代的醛上，采用平行合成的方法制备一系列3-（乙酰硫基）-2-烷基链烷醛，这些醛是通过相应的醛醇缩合反应制得的伯醛为原料。根据GC，MS和NMR数据对目标化合物进行了表征。由训练有素的小组来确定气味的感官特性，例如气味质量和气味检测阈值。讨论了结构-活性关系，表明热带/植物味的“嗅觉基团”所需的1,3-氧-硫官能度可进一步扩展至乙酰硫基衍生物。
• Rapid Organocatalytic Aldehyde-Aldehyde Condensation Reactions
  作者：Anniina Erkkilä、Petri M. Pihko

  DOI：10.1002/ejoc.200700292

  日期：2007.9

  We report the results of the systematic optimization of the α-methylenation of aldehydes with aqueous formaldehyde. A simple combination of a secondary amine catalyst and a weak acid co-catalyst has been identified, allowing access to α-substituted acroleins in a matter of minutes. In the absence of formaldehyde, the catalytic system promoted the self-condensation reaction of α,β-unsaturated aldehydes

  我们报告了醛类与甲醛水溶液的 α-甲基化的系统优化结果。已经确定了仲胺催化剂和弱酸助催化剂的简单组合，可以在几分钟内获得 α-取代的丙烯醛。在没有甲醛的情况下，催化体系促进了 α,β-不饱和醛的自缩合反应。这两个反应都表现出助催化剂酸度和反应速率之间的线性关系。观察到催化剂浓度的二级依赖性，表明在速率确定步骤中涉及两个铵催化剂分子。(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。