O¹-methyl-D-fructose | 55905-50-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: O¹-methyl-D-fructose
• 英文别名: D-arabino-3,4,5,6-Tetrahydroxy-1-methoxy-hexan-2-on；1-O-Methylfructose；(3S,4R,5R)-3,4,5,6-tetrahydroxy-1-methoxyhexan-2-one
• CAS: 55905-50-5
• 化学式: C₇H₁₄O₆
• 分子量: 194.185
• InChiKey: RZQDQBCUXSKCRV-QPPQHZFASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  107
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  O¹-methyl-D-fructose 在 乙醇 、 镍 作用下， 生成 1-O-Methyl-D-mannit
  参考文献：
  名称：

  Bayne; Wildy, Journal of the Chemical Society, 1954, p. 1147

  摘要：

  DOI：
• 作为产物：
  描述：

  果糖 在 sodium hydroxide 、 硫酸 、 phosphorus pentoxide 、 丙酮 、 硫酸二甲酯 、 zinc(II) chloride 作用下， 生成 O¹-methyl-D-fructose
  参考文献：
  名称：

  Glen et al., Journal of the Chemical Society, 1951, p. 2568,2570

  摘要：

  DOI：

文献信息

• [EN] ISOMERISATION OF C4-C6 ALDOSES WITH ZEOLITES<br/>[FR] ISOMÉRISATION D'ALDOSES EN C4-C6 AVEC DES ZÉOLITES
  申请人：UNIV DANMARKS TEKNISKE

  公开号：WO2014033311A1

  公开（公告）日：2014-03-06

  The present invention relates to isomerization of C4-C6 aldoses to their corresponding C4-C6 ketoses. In particular, the invention concerns isomerization of C4-C6 aldoses over solid zeolite catalysts free of any metals other than aluminum, in the presence of suitable solvent(s) at suitable elevated temperatures. C6 and C5 aldose sugars such as glucose and xylose, which are available in large amounts from biomass precursors, are isomerized to fructose and xylulose respectively, in a one or two-step process over inexpensive commercially available zeolite catalysts, containing aluminum as the only metal in the catalyst. The ketoses obtained are used as sweeteners in the food and/or brewery industry, or treated to obtain downstream platform chemicals such as lactic acid, HMF, levulinic acid, furfural, MMHB, and the like. FIG. 7

  本发明涉及将C4-C6醛糖异构化为它们对应的C4-C6酮糖。具体而言，该发明涉及在适当的溶剂存在下，在适当的升温条件下，将C4-C6醛糖在除铝以外没有任何金属的固体沸石催化剂上进行异构化。来自生物质前体的大量C6和C5醛糖，如葡萄糖和木糖，通过一步或两步过程在廉价的商业可获得的仅含铝作为催化剂中唯一金属的沸石催化剂上分别异构化为果糖和木糖醛。所得的酮糖被用作食品和/或啤酒行业的甜味剂，或者经处理以获得下游平台化学品，如乳酸、HMF、乙酰丁酸、糠醛、MMHB等。图7
• Process for Producing D-Mannitol
  申请人：Weymarn Niklas von

  公开号：US20110091949A1

  公开（公告）日：2011-04-21

  High concentration of free cells of heterofermentative lactic acid bacteria (LAB) in a resting or slowly growing state are used to convert fructose into mannitol. Efficient volumetric mannitol productivities and mannitol yields from fructose are achieved in a process applying cell-recycle, continuous stirred tank reactor and/or circulation techniques with native LAB cells or with LAB cells with inactivated fructokinase gene(s). Mannitol is recovered in high yield and purity with the aid of evaporation and cooling crystallization.

  高浓度的自由异养乳酸菌（LAB）细胞，以静止或缓慢生长状态用于将果糖转化为甘露醇。通过应用细胞回收、连续搅拌槽反应器和/或循环技术，使用原生LAB细胞或具有灭活果糖激酶基因的LAB细胞，实现了高效的体积甘露醇生产率和甘露醇收率。利用蒸发和冷却结晶技术，高收率和高纯度地回收甘露醇。
• ISOMERISATION OF C4-C6 ALDOSES WITH ZEOLITES
  申请人：DANMARKS TEKNISKE UNIVERSITET

  公开号：US20150232498A1

  公开（公告）日：2015-08-20

  The present invention relates to isomerization of C4-C6 aldoses to their corresponding C4-C6 ketoses. In particular, the invention concerns isomerization of C4-C6 aldoses over solid zeolite catalysts free of any metals other than aluminum, in the presence of suitable solvent(s) at suitable elevated temperatures. C6 and C5 aldose sugars such as glucose and xylose, which are available in large amounts from biomass precursors, are isomerized to fructose and xylulose respectively, in a one or two-step process over inexpensive commercially available zeolite catalysts, containing aluminum as the only metal in the catalyst. The ketoses obtained are used as sweeteners in the food and/or brewery industry, or treated to obtain downstream platform chemicals such as lactic acid, HMF, levulinic acid, furfural, MMHB, and the like.

  本发明涉及将C4-C6醛糖异构化为相应的C4-C6酮糖。特别是，本发明涉及在适当的溶剂存在下，在适当的升温条件下，通过不含任何铝以外金属的固体沸石催化剂对C4-C6醛糖的异构化。从生物质前体中大量获得的C6和C5醛糖，如葡萄糖和木糖，通过廉价的商业化沸石催化剂进行一步或两步过程的异构化，分别转化为果糖和木酮糖。所获得的酮糖可用作食品和/或啤酒工业的甜味剂，或处理以获得下游平台化学品，例如乳酸、HMF、左旋肉碱酸、糠醛、MMHB等。
• Improved production of vanilloids by fermentation
  申请人：Rhodia Opérations

  公开号：EP2957629A1

  公开（公告）日：2015-12-23

  The present invention concerns a recombinant yeast comprising a set of exogenous nucleic acids, with each nucleic acid encoding a polypeptide involved in the biosynthesis pathway of a vanilloid, said set of exogenous nucleic acids encoding a set of polypeptides selected in a group comprising: • a set of enzymes allowing conversion of an aromatic amino acid into a vanilloid; and • a set of enzymes allowing conversion of a dehydroshikimic acid into a vanilloid; and wherein said recombinant yeast is devoid of a functional gene adh6 encoding for an alcohol dehydrogenase, and wherein said recombinant yeast has a reduced ability to decarboxylate phenylacrylic acids, which encompasses that said yeast does not comprise a fonctional fdc1 gene and/ or a functional pad1 gene.

  本发明涉及一种重组酵母，该重组酵母包含一组外源核酸，每个核酸编码参与类香草素生物合成途径的多肽，所述的一组外源核酸编码一组多肽，这组多肽选自以下组别，包括 - 一组可将芳香族氨基酸转化为香草酸的酶；以及 - 一组可将脱水莽草酸转化为香草酸的酶； 其中所述重组酵母没有编码醇脱氢酶的功能基因 adh6、 其中所述重组酵母的苯丙烯酸脱羧能力降低，包括所述酵母不包含功能性 fdc1 基因和/或功能性 pad1 基因。
• Isomerisation of C4-C6 aldoses with zeolites
  申请人：DANMARKS TEKNISKE UNIVERSITET

  公开号：US10246477B2

  公开（公告）日：2019-04-02

  The present invention relates to isomerization of C4-C6 aldoses to their corresponding C4-C6 ketoses. In particular, the invention concerns isomerization of C4-C6 aldoses over solid zeolite catalysts free of any metals other than aluminum, in the presence of suitable solvent(s) at suitable elevated temperatures. C6 and C5 aldose sugars such as glucose and xylose, which are available in large amounts from biomass precursors, are isomerized to fructose and xylulose respectively, in a one or two-step process over inexpensive commercially available zeolite catalysts, containing aluminum as the only metal in the catalyst. The ketoses obtained are used as sweeteners in the food and/or brewery industry, or treated to obtain downstream platform chemicals such as lactic acid, HMF, levulinic acid, furfural, MMHB, and the like.

  本发明涉及将 C4-C6 醛类异构化为相应的 C4-C6 酮类。具体而言，本发明涉及在适当的溶剂存在下，在适当的高温条件下，在不含铝以外任何金属的固体沸石催化剂上进行 C4-C6 醛糖异构化。可从生物质前体中大量获得的 C6 和 C5 醛糖，如葡萄糖和木糖，可在价格低廉的市售沸石催化剂（催化剂中唯一的金属是铝）上，通过一步或两步工艺分别异构化为果糖和木糖。获得的酮糖可用作食品和/或酿酒工业的甜味剂，或经处理后获得下游平台化学品，如乳酸、HMF、乙酰丙酸、糠醛、MMHB 等。