1,4,4-trimethyl-1-hydroxymethylcyclohexane | 140423-44-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4,4-trimethyl-1-hydroxymethylcyclohexane
• 英文别名: (1,4,4-Trimethylcyclohexyl)methanol；(1,4,4-trimethylcyclohexyl)methanol
• CAS: 140423-44-5
• 化学式: C₁₀H₂₀O
• 分子量: 156.268
• InChiKey: JJKFTIOXFNDSOA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1,4,4-trimethyl-8-oxabicyclo<5.1.0>octane 在 rhenium(VII) oxide 作用下， 反应 1.0h， 以45%的产率得到环己甲醛,1,4,4-三甲基-
  参考文献：
  名称：

  Manukov, E. N.; Bazhina, G. N., Russian Journal of Organic Chemistry, 1991, vol. 27, # 7.1, p. 1260 - 1264

  摘要：

  DOI：

文献信息

• PYRAZOLE CARBOXAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE
  申请人：Genentech, Inc.

  公开号：US20150158851A1

  公开（公告）日：2015-06-11

  Provided herein are compounds of formula (AA): stereoisomers or a pharmaceutically acceptable salt thereof, wherein A, R a , p, R 5 and R 6 are defined herein, compositions including the compounds and methods of manufacturing and using the compounds for the treatment of diseases.

  本文提供了式（AA）的化合物：其立体异构体或其药学上可接受的盐，其中A、Ra、p、R5和R6在此定义，包括该化合物的组合物以及制造和使用该化合物治疗疾病的方法。
• [EN] DENDRIMERS WITH INTERIOR AND EXTERIOR FUNCTIONALITIES COMPRISING OF AZIDE OR ALKYNE GROUPS FOR POST- FUNCTIONALIZATION BY HUISGEN CLICK CYCLOADDITION<br/>[FR] STRUCTURES DENDRITIQUES AYANT DES FONCTIONNALITÉS INTÉRIEURES ET EXTÉRIEURES
  申请人：POLYMER FACTORY SWEDEN AB

  公开号：WO2009136853A1

  公开（公告）日：2009-11-12

  There is disclosed a dendritic structure, said dendritic structure comprising a core and repeating units, wherein the repeating units comprise units of the type ABxCy, wherein x is 2, 3, or 4, wherein y is 1, 2, or 3, wherein C is selected from the group consisting of azides and alkynes, and wherein every repeating unit is bound to at least one other unit with at least one bond selected from the group consisting of the group consisting of an ester, an amide, a thioether, an ether, a urethane, an amine, and an imine. There is also provided use of the dendritic structures. Advantages include that a "one-pot" growth of the dendritic structure is possible. It is possible to have more functional groups in a dendritic structure. It is possible to add different functional groups simultaneously both to an inner layer and to an outer layer in a dendritic structure.