vinyl 2-phenoxyacetate | 4054-77-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: vinyl 2-phenoxyacetate
• 英文别名: vinyl phenoxyacetate；Phenoxyessigsaeure-vinylester；ethenyl 2-phenoxyacetate
• CAS: 4054-77-7
• 化学式: C₁₀H₁₀O₃
• 分子量: 178.188
• InChiKey: UYCXQYROAOOUKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  vinyl 2-phenoxyacetate 、 (3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazole-6,7-diol 在 sodium carbonate 作用下， 以 丙酮 为溶剂， 反应 16.0h， 以70%的产率得到((3aR,5R,6S,7R,7aR)-6,7-dihydroxy-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d]thiazol-5-yl)methyl 2-phenoxyacetate
  参考文献：
  名称：

  Enzymatic synthesis of new C-6-acylated derivatives of NAG-thiazoline and evaluation of their inhibitor activities towards fungal β-N-acetylhexosaminidase

  摘要：

  beta-N-Acetylhexosaminidases (EC 3.2.1.52) from the CAZy glycoside hydrolase families 20 and 84 are two distinct enzyme groups with similar reactivity and different physiological functions, thus selective inhibition of these enzymes is of crucial importance. Here, we report on the lipase-catalyzed synthesis of a set of novel monomeric and dimeric C-6-acylated derivatives of NAG-thiazoline, which is a typical competitive inhibitor of both these enzyme classes. The prepared compounds were tested as potential inhibitors of a fungal GH20 beta-N-acetylhexosaminidase from Talaromyces flavus, however, the results of the inhibition tests were quite ambiguous. The observed inhibition was generally weak with some features of competitive inhibition (increase of K-M), but the overall pattern appeared indecisive. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcatb.2012.10.016
• 作为产物：
  描述：

  乙酸乙烯酯 、 苯氧乙酸 在 palladium diacetate 作用下， 以 四氢呋喃 为溶剂， 反应 16.0h， 以72%的产率得到vinyl 2-phenoxyacetate
  参考文献：
  名称：

  Enzymatic synthesis of new C-6-acylated derivatives of NAG-thiazoline and evaluation of their inhibitor activities towards fungal β-N-acetylhexosaminidase

  摘要：

  beta-N-Acetylhexosaminidases (EC 3.2.1.52) from the CAZy glycoside hydrolase families 20 and 84 are two distinct enzyme groups with similar reactivity and different physiological functions, thus selective inhibition of these enzymes is of crucial importance. Here, we report on the lipase-catalyzed synthesis of a set of novel monomeric and dimeric C-6-acylated derivatives of NAG-thiazoline, which is a typical competitive inhibitor of both these enzyme classes. The prepared compounds were tested as potential inhibitors of a fungal GH20 beta-N-acetylhexosaminidase from Talaromyces flavus, however, the results of the inhibition tests were quite ambiguous. The observed inhibition was generally weak with some features of competitive inhibition (increase of K-M), but the overall pattern appeared indecisive. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcatb.2012.10.016

文献信息

• Unsaturatd sugar compounds
  申请人：Hoechst Aktiengesellschaft

  公开号：US05496930A1

  公开（公告）日：1996-03-05

  A process for highly regioselective esterification and ester cleavage on unsaturated sugar compounds with the aid of lipases and esterases, and products which can be prepared by this process. Highly regioselective esterifications and ester cleavages can be carried out on unsaturated sugar compounds with the aid of lipases and esterases. Lipases from microorganisms or from the pancreas and liver of animals are preferably used.

  利用脂肪酶和酯酶在不饱和糖化合物上进行高度区域选择性的酯化和酯裂解的方法，以及可以通过该方法制备的产品。利用微生物或动物胰腺和肝脏中的脂肪酶进行高度区域选择性的酯化和酯裂解。
• Heat-fixable electrophotographic toner
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0183566A2

  公开（公告）日：1986-06-04

  A heat-flexible electrophotographic toner composition comprising (A) a graft modified polyolefin composed of 100 parts by weight of a polyolefin having an intrinsic viscosity, measured in decalin at 135°C, of from 0.04 to 1.2 dl/g, and grafted thereto a monomer selected from the group consisting of (a) 1.0 to 100 parts by weight of acrylonitrile or methacrylonitrile, (b) 3 to 200 parts by weight of an aromatic carboxylic acid vinyl ester and (c) 2 to 43 parts by weight of an unsaturated carboxylic acid ester, and (B) a coloring agent.

  一种热柔性电子照相调色剂组合物，包括 (A) 一种接枝改性聚烯烃，由 100 重量份的聚烯烃组成，该聚烯烃在 135 摄氏度下以癸醛计的固有粘度为 0.04 至 1.2 分升/克，并接枝了选自以下组别的单体 (a) 1.0 至 100 份（按重量计）丙烯腈或甲基丙烯腈，(b) 3 至 200 份（按重量计）芳香族羧酸乙烯基酯，(c) 2 至 43 份（按重量计）不饱和羧酸酯。 (B) 着色剂。
• Adhesive for chlorine-containing polymers and aromatic group-containing polymers
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0181094A1

  公开（公告）日：1986-05-14

  Disclosed is a thermoplastic adhesive comprising a modified polyolefin resin having a branch chain having at least one carbonyl group and at least one benzene nucleus in one side chain. This adhesive shows a strong bonding force to a chlorine-containing polymer or an aromatic group-containing polymer such as a polyester and is especially valuable for the production of a laminate of such a resin and a polyolefin. A blend or block copolymer comprising an olefin resin component that can contain a carboxyl group and a carbon-to-carbon chain resin component having a benzoic acid ester or cinnamic acid ester group in the side chain is especially excellent in the bonding characteristics, particularly the heat-resistance adhesion.

  本发明公开了一种热塑性粘合剂，该粘合剂由改性聚烯烃树脂组成，改性聚烯烃树脂的一条侧链上具有至少一个羰基和至少一个苯核的支链。 这种粘合剂与含氯聚合物或含芳香族基团的聚合物（如聚酯）具有很强的粘合力，特别适用于生产这种树脂与聚烯烃的层压板。 由可含有羧基的烯烃树脂组分和侧链上具有苯甲酸酯或肉桂酸酯基团的碳-碳链树脂组分组成的共混物或嵌段共聚物在粘合特性，特别是耐热粘合性方面尤为出色。
• Lipase-catalyzed transesterification of 2-phenyl-1-propanol with vinyl esters having aromatic ring in acyl moiety
  作者：Masashi Kawasaki、Michimasa Goto、Shigeki Kawabata、Tomoko Kodama、Tadashi Kometani

  DOI：10.1016/s0040-4039(99)00943-0

  日期：1999.7

  The highly enantioselective transesterification of 2-phenyl-1-propanol, which has not been efficiently resolved by lipase-catalyzed reactions, was attained by using either vinyl 3-(p-tolyl)propanoate or vinyl 3-(2-naphthyl)propanoate as the acyl donor. (C) 1999 Elsevier Science Ltd. All rights reserved.
• HOLLA, E. WOLFGANG, J. CARBOHYDR. CHEM., 9,(1990) N, C. 113-119
  作者：HOLLA, E. WOLFGANG

  DOI：——

  日期：——