trans-4-n-pentylcyclohexylcarbonyl chloride | 67679-85-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: trans-4-n-pentylcyclohexylcarbonyl chloride
• 英文别名: trans-4-pentylcyclohexane carboxylic acid chloride；trans-4-pentylcyclohexylcarbonyl chloride；trans-4-pentylcyclohexane-1-carbonyl chloride；4-pentylcyclohexane-1-carbonyl chloride
• CAS: 67679-85-0
• 化学式: C₁₂H₂₁ClO
• 分子量: 216.751
• InChiKey: PPWKQEDYUMJFNK-UHFFFAOYSA-N

物化性质

• 沸点：
  271.7±9.0 °C(Predicted)
• 密度：
  0.986±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  trans-4-n-pentylcyclohexylcarbonyl chloride 在 sodium carbonate 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 12.0h， 以57%的产率得到(S)-3-(4'-pentyl[2,2,2]bicyclo-octane-1-carbonyl)amino-caprolactam
  参考文献：
  名称：

  [EN] ANTI-INFLAMMATORY AGENTS
  [FR] AGENTS ANTI-INFLAMMATOIRES

  摘要：

  本发明提供了通式（I）的化合物、组合物及其药学上可接受的盐的用途，其中X为-CO-Y-(R1)n或SO2-Y-(R1)n；Y为0环烷基或多环烷基（例如，金刚烷基，金刚烷甲基，双环辛基，环己基，环丙基）；或为0环烯基或多环烯基。这些化合物是3-氨基己内酯衍生物，用于制备用于治疗炎症性疾病的药物。

  公开号：

  WO2006016152A1
• 作为产物：
  描述：

  4-正戊基苯甲酸 在 铑 氯化亚砜 、 氢气 作用下， 生成 trans-4-n-pentylcyclohexylcarbonyl chloride
  参考文献：
  名称：

  Margerum; Wong; Lackner, Molecular Crystals and Liquid Crystals (1969-1991), 1980, vol. 68, # 1-4, p. 157 - 174

  摘要：

  DOI：

文献信息

• [EN] LIQUID CRYSTAL COMPOUND COMPRISING TWO CONDENSED AND SUBSTITUTED RINGS<br/>[FR] COMPOSÉ DE CRISTAUX LIQUIDES COMPRENANT DEUX CYCLES CONDENSÉS ET SUBSTITUÉS
  申请人：FUJI PHOTO FILM CO LTD

  公开号：WO2005085222A1

  公开（公告）日：2005-09-15

  A new liquid crystal compound comprises two condensed and substituted rings. The ring preferably is a five-membered heterocyclic ring. The heterocyclic ring is preferably condensed with benzene ring or an aromatic six-membered heterocyclic ring. The benzene ring or the aromatic six-membered heterocyclic ring is preferably substituted with a group comprising a cyclic structure and a chain structure. The liquid crystal compound is advantageously used in preparation of a thin phase retarder, such as a wide-ranged l/4 plate, which gives inverse wavelength distribution. The phase retarder can be easily produced according to a simple process by using the new liquid crystal compound.

  一种新的液晶化合物包括两个凝缩和取代的环。该环最好是一个五元杂环。该杂环最好与苯环或芳香六元杂环凝缩。苯环或芳香六元杂环最好取代为一个包含环结构和链结构的基团。该液晶化合物有利地用于制备薄相位延迟器，如宽范围的1/4波片，其提供反向波长分布。根据使用新的液晶化合物可以通过简单的工艺容易地生产相位延迟器。
• Substituted amino alcohols as chiral dopants
  申请人：Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung E.V.

  公开号：US09273247B2

  公开（公告）日：2016-03-01

  The invention relates to the use of a substituted, chiral amino alcohol, comprising one or more structural units of the following formula (1), wherein the abbreviations A, Y, R1 and R3 to R5 have the following meanings: is a covalent bond or a hydrocarbon group, Y is a covalent bond or a hydrocarbon group that can have an oxygen atom at one of its ends through which it is bonded to R1, R1 is an aliphatic or heterocyclic or aromatic radical, the carbon chain of which may be interrupted by one or more B groups, R5 is selected from the group consisting of (a) aliphatic radicals, wherein individual carbon atoms may be replaced by oxygen atoms or carbonyl groups, and wherein the carbon chains of same radicals may be optionally interrupted by a B group, and (b) araliphatic, cycloaliphatic, aromatic and heterocyclic radicals, wherein the carbon chain can be interrupted by one or more B structural elements and/or by one or more D coupling groups, R3, R4 are hydrogen or aliphatic or araliphatic substituents, which are independent of one another, wherein the carbon chain can be interrupted by one or more B groups, B is selected from polymerizable or crosslinkable structural elements from the group comprising C1-C16-alkenyl, C1-C16-alkenyloxy, —C═C—, —CH═CH—COO—, —CH═CH—, —CX═CH—COO— with X═C1-C16-alkyl, and the trans-form of —OOC—CH═CH—COO—, and D is selected from —O—, —NH—, —N(CH3)—, —N(C2H5)—, —SO2—, —CO—, —COO—, —CH═CH—, —OCOO—, —OCH2—, CH═N, —CF2CF2—, as a chiral dopant in liquid crystal (mixtures), e.g., in electro-optical systems.

  该发明涉及使用一种取代的手性氨基醇，包括以下式（1）的一个或多个结构单元，其中缩写A、Y、R1和R3至R5具有以下含义：A是共价键或碳氢基团，Y是共价键或碳氢基团，可以在其一端具有氧原子，通过该氧原子与R1键合，R1是脂肪族、杂环或芳香基，其碳链可能被一个或多个B基团中断，R5选自以下组成的群体：（a）脂肪基，其中个别碳原子可被氧原子或羰基取代，同一基团的碳链可能选择性地被B基团中断；（b）芳基脂肪族、环脂肪族、芳香和杂环基，其碳链可被一个或多个B结构元素和/或一个或多个D偶联基中断，R3、R4是氢或脂肪族或芳基脂肪族取代基，彼此独立，其碳链可能被一个或多个B基团中断，B选自以下群体中的可聚合或可交联的结构单元：C1-C16-烯基、C1-C16-烯氧基、—C═C—、—CH═CH—COO—、—CH═CH—、—CX═CH—COO—，其中X=C1-C16-烷基，以及—OOC—CH═CH—COO—的反式形式，D选自—O—、—NH—、—N(CH3)—、—N(C2H5)—、—SO2—、—CO—、—COO—、—CH═CH—、—OCOO—、—OCH2—、CH═N、—CF2CF2—，作为液晶（混合物）中的手性掺杂剂，例如在电光系统中。
• Aliphatic Liquid Crystals with Positive Dielectric Anisotropy
  作者：Maged A. Osman、T. Huynh-Ba

  DOI：10.1002/hlca.19840670407

  日期：1984.6.20

  derivatives. (Cyanoethyl)cyclohexyl cyclohenxanoates show mesmorphic properties in contrast to the corresponding cyano derivative. Separation of the cyano substituent from the rigid core of an anisotropic aliphatic compound by methylene groups enhances the thermodynamic stability of the mesophase. In aromatic compound, the cyanoethyl group leads to lower clearing points. These phenomena are attributed to teh

  合成了氰基取代的环己基环己酸酯，双（环己烷）和苯基环己烷。将它们的同晶行为与相应的氰基衍生物的同晶行为进行比较。与相应的氰基衍生物相反，（氰乙基）环己基环己酸酯具有同晶型性质。通过亚甲基将氰基取代基与各向异性脂族化合物的刚性核分离，可以增强中间相的热力学稳定性。在芳族化合物中，氰基乙基导致较低的透明点。这些现象归因于空间效应对堆积密度的影响以及清除点对分子缔合的依赖性。
• Liquid crystal composition, liquid crystal device, display apparatus and
  申请人：Canon Kabushiki Kaisha

  公开号：US05217643A1

  公开（公告）日：1993-06-08

  A mesomorphic liquid crystal composition stably exhibits lowered resistivity for quickly attenuating a reverse voltage caused by charge localization.

  一种介向液晶组合物能够稳定地表现出降低电阻率的特性，以迅速消减由电荷局部化引起的反向电压。
• Liquid crystal device and liquid crystal apparatus
  申请人：Canon Kabushiki Kaisha

  公开号：US05858269A1

  公开（公告）日：1999-01-12

  A liquid crystal device is constituted by a pair of substrates each having thereon at least an electrode and an alignment control layer, and a liquid crystal composition disposed between the substrates. At least one of the alignment control layers has a thickness of at most 200 .ANG. or comprises polyimide. In the latter case, the pair of substrates have been subjected to mutually different aligning treatments. The liquid crystal composition comprises at least one species of a fluorine-containing mesomorphic compound in an amount of at least 70 wt. % comprising a fluorocarbon terminal portion and a hydrocarbon terminal portion, the terminal portions being connected with a central core, and having smectic mesophase or latent smectic mesophase, and comprises at least one species of a resistivity-modifying substance. The fluorine-containing mesomorphic compound comprises a compound having a fluorocarbon terminal portion containing at least one catenary ether oxygen atom in an amount of at least 30 wt. % based on the liquid crystal composition. The liquid crystal device is effective in improving switching characteristics, an alignment characteristic and display performances while retaining a bookshelf structure or a near bookshelf structure with respect to a smectic layer structure.

  一种液晶装置由一对基板构成，每个基板上至少有一个电极和一个定向控制层，并在基板之间放置一种液晶组合物。至少一个定向控制层的厚度不超过200埃或包含聚酰亚胺。在后一种情况下，基板对已经经过互相不同的定向处理。液晶组合物包括至少一种含氟介相化合物，其含氟碳端部和烃端部，端部与中心核相连，含有薄层介相或潜在薄层介相，占至少70重量％，并包括至少一种电阻率调节物质。含氟介相化合物包括一种含有至少30重量％的链醚氧原子的含氟碳端部化合物，基于液晶组合物。该液晶装置在保持书架结构或近书架结构的同时，有效改善开关特性、定向特性和显示性能。