N-cyclopentyl-1-(pyridin-2-yl)methanimine | 1162789-10-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-cyclopentyl-1-(pyridin-2-yl)methanimine
• 英文别名: N-cyclopentyl-1-pyridin-2-ylmethanimine
• CAS: 1162789-10-7
• 化学式: C₁₁H₁₄N₂
• 分子量: 174.246
• InChiKey: BQSCCJHDFILGMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  25.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-cyclopentyl-1-(pyridin-2-yl)methanimine 、 zinc(II) chloride 以 乙醇 为溶剂， 反应 12.0h， 以96.6%的产率得到N-cyclopentyl-1-(pyridin-2-yl)methanimine(dichloro)zinc(II) chloride
  参考文献：
  名称：

  Cd(II) and Zn(II) Complexes Containing N,N'-Bidentate N-(Pyridin-2-ylmethylene)cyclopentanamine: Synthesis, Characterisation and Methyl Methacrylate Polymerisation

  摘要：

  $[CdBr_2\{cdot}4H_2O]$ 和无水 $[ZnCl_2]$在乙醇中与 N、N'-bidentate N-(吡啶-2-基亚甲基)-环戊胺 (impy) 在乙醇中分别生成二聚体 $[(impy)Cd({\mu}-Br)Br]_2$和单体 $[(impy)ZnCl_2]$复合物。镉（II）和锌（II）配合物的 X 射线晶体结构显示，$[(impy)Cd({\mu}-Br)Br]_2$中的镉原子和 $[(impy)ZnCl_2]$中的锌原子分别形成了扭曲的三叉双锥和四面体几何结构。在改性甲基铝氧烷（MMAO）存在下，这两种配合物在甲基丙烯酸甲酯（MMA）的聚合反应中都表现出中等催化活性，聚甲基丙烯酸甲酯（PMMA）的联合活性约为 0.70。

  DOI：

  10.5012/bkcs.2014.35.10.2929
• 作为产物：
  描述：

  吡啶-2-甲醛 、 环戊胺 以 二氯甲烷 为溶剂， 反应 48.0h， 生成 N-cyclopentyl-1-(pyridin-2-yl)methanimine
  参考文献：
  名称：

  亲脂性吡啶甲羧二胺铂（II）配合物的合成，表征和抗癌活性

  摘要：

  摘要我们从2-吡啶甲醛与相应的亲脂性伯胺的缩合反应中制得了11种吡啶甲二胺（N-N'R）。将这些配体添加到[PtCl 2（η2 -coe）] 2（coe =顺式环辛烯）中，得到中等至高产率的顺式-PtCl 2（N-N'R）（2a-k）型配合物。通过X射线衍射研究已经确认了N-丁基苯基衍生物（2h）的分子结构。2h晶体是单斜晶，在空间群P 2（1）/ c中a = 8.5414（9）A，b = 11.6774（12）A，c = 16.1235（16）A，β= 92.7610（10）°。检查所有铂配合物对两种人成胶质细胞瘤多形细胞系LN18和LN405的体外细胞毒性。比较了一种最具细胞毒性的化合物与顺铂的DNA结合特性，

  DOI：

  10.1016/j.poly.2015.07.039

文献信息

• Synthesis and characterization of half-sandwich ruthenium(II) complexes with N-alkyl pyridyl-imine ligands and their application in transfer hydrogenation of ketones
  作者：Joel M. Gichumbi、Holger B. Friedrich、Bernard Omondi

  DOI：10.1007/s11243-016-0089-5

  日期：2016.11

  The complexes were fully characterized by 1H NMR and 13C NMR, UV–Vis and IR spectroscopies, elemental analyses, and the single-crystal X-ray structures of 2a and 2b have been determined. The single-crystal molecular structure revealed both compounds with a pseudo-octahedral geometry around the Ru(II) center, normally referred to as a piano stool conformation, with the pyridyl-imine as a bidentate N

  通过通式[(η6-芳烃)Ru(μ-Cl)Cl]2的钌(II)前体与N,N'-二齿吡啶基-亚胺配体反应制备了一系列新的芳烃钌(II)配合物形成 [(η6-芳烃)RuCl(C5H4N-2-CH=NR)]PF6 类型的配合物，芳烃 = C6H6，R = 异丙基 (1a)、叔丁基 (1b)、环己基 (1c) 、环戊基(1d)和正丁基(1e)；芳烃 = 对伞花烃，R = 异丙基 (2a)，叔丁基 (2b)。配合物通过 1H NMR 和 13C NMR、UV-Vis 和 IR 光谱、元素分析和 2a 和 2b 的单晶 X 射线结构进行了充分表征。单晶分子结构揭示了两种化合物在 Ru(II) 中心周围具有伪八面体几何形状，通常称为钢琴凳构象，吡啶亚胺作为双齿 N,N 配体。报告了在 NaOH 和异丙醇存在下所有配合物在环己酮转移氢化中的活性，这些化合物的转化率接近 1990，转化率高。复合物 2b 也被
• Polymerizations of methyl methacrylate and <i>rac</i>-lactide by zinc(II) precatalyst containing <i>N</i>-substituted 2-iminomethylpyridine and 2-iminomethylquinoline
  作者：Joung Heo、Hyosun Lee、Saira Nayab

  DOI：10.1080/00958972.2017.1416106

  日期：2017.12.2

  effective for polymerization of methyl methacrylate (MMA) and polymerization of rac-lactide (rac-LA). [LCZnCl2] (with N-cyclohexyl substituted at imine-pyridine moiety) exhibited the highest catalytic activity for MMA polymerization in the presence of modified methylaluminoxane (MMAO) with an activity of 3.33 × 104 g PMMA/mol·Zn·h at 60 °C, giving moderate syndiotactic poly methyl methacrylate (PMMA) with

  摘要 [ZnCl2]与N-环戊基-1-(喹啉-2-基)甲胺(LA)、N-环己基-1-(喹啉-2-基)甲胺(LB)、N-环己基-1-的反应(pyridin-2-yl)methanimine (LC), 2,6-diethyl-N-(pyridin-2-ylmethylene)aniline (LD), N-cyclopentyl-1-(pyridin-2-yl)methanimine (LE),和 N-苯基-(吡啶-2-基)甲胺 (LF) 在乙醇中产生二齿 [(NN')ZnCl2] 络合物、[LAZnCl2]、[LBZnCl2]、[LCZnCl2]、[LDZnCl2]、[LEZnCl2] 和[LFZnCl2]，分别。分子结构表明，[LnZnCl2] (Ln = LA - LD) 中的锌表现出扭曲的四面体几何形状，包括两个 N,N'-二齿配体的氮和两个氯化物配体。大多数这些引发剂对于甲基丙烯酸甲酯
• Synthesis, characterization and antimicrobial properties of lipophilic palladium complexes bearing iminopyridine ligands
  作者：Patrick T. Gormley、B. Ninh Khuong、Courtney M. Dickie、Ashley M. Taweel、Heather L. Blundon、Josée-Marie E. J. Melanson、Adam F. LeBlanc、Tara S. Murphy、Curran G. Tompkins、Christopher M. Vogels、Andreas Decken、Felix J. Baerlocher、Tyson J. MacCormack、Stephen A. Westcott

  DOI：10.1007/s11243-015-9977-3

  日期：2015.11

  The reaction of [PdCl2(η2-coe)]2 (coe = cis-cyclooctene) with nine lipophilic iminopyridine ligands (NN′, 1a–i) afforded the corresponding metal complexes cis-[PdCl2(NN′)] (2a–i) with concomitant loss of the labile coe ligands. All iminopyridine complexes were characterized by physicochemical and spectroscopic methods. The molecular structures of two complexes, 2a and 2b, were determined by single

  [PdCl2(η2-coe)]2 (coe = cis-cyclooctene) 与九个亲脂性亚氨基吡啶配体 (NN', 1a-i) 反应得到相应的金属配合物 cis-[PdCl2(NN')] (2a-i ) 伴随着不稳定的 coe 配体的丢失。所有亚氨基吡啶配合物均通过物理化学和光谱方法表征。通过单晶 X 射线衍射研究确定了两种配合物 2a 和 2b 的分子结构。测试了所有复合物的潜在抗真菌和抗菌活性。
• Palladium(II) complexes containing N,N′-bidentate N-cycloalkyl 2-iminomethylpyridine and 2-iminomethylquinoline: Synthesis, characterisation and methyl methacrylate polymerisation
  作者：Sunghoon Kim、Eunhee Kim、Ha-Jin Lee、Hyosun Lee

  DOI：10.1016/j.poly.2013.11.036

  日期：2014.2

  The reaction of [Pd(CH3CN)(2)Cl-2] with N-cyclopentyl-1-(pyridin-2-yl)methanimine (L-1), N-cyclohexyl-1-(pyridin-2-yl)methanimine (L-2), N-(piperidin-1-yl)-1-(pyridin-2-yl)methanimine (L-3) or N-cyclopentyl-1-(quinolin-2-yl)methanimine (L-4) in ethanol yields the bidentate (NN') PdCl2 complexes [L1PdCl2], [L2PdCl2], [L3PdCl2] and [L4PdCl2), respectively. The X-ray crystal structure of the Pd(II) complexes revealed that the Pd atom in [LnPdCl2] (L-n = L-1, L-2, L-3, L-4) shows a distorted square planar geometry involving two nitrogen atoms and two chloro ligands. The complexes [L1PdCl2] and [L4PdCl2] (of which the ligands are N-cyclopentyl substituted) showed the highest catalytic activity for the polymerisation of methyl methacrylate (MMA) in the presence of modified methylaluminoxane (MMAO) with an activity of 1.45 x 10(5) g PMMA/mol Pd h at 60 degrees C and a PMMA syndiotacticity (characterized using C-13 NMR spectroscopy) of ca. 0.70. (C) 2013 Elsevier Ltd. All rights reserved.
• Structure-dependent spectroscopic and redox properties of copper(I) complexes with bidentate iminopyridine ligands
  作者：Werner Massa、Saeed Dehghanpour、Khadijeh Jahani

  DOI：10.1016/j.ica.2009.01.008

  日期：2009.6

  A series of iminopyridine ligands; cyclopropylpyridin-2-ylmethyleneamine (A), cyclopentylpyridin-2-ylmethyleneamine (B), cyclohexylpyridin-2-ylmethyleneamine (C), and cycloheptylpyridin-2-ylmethyleneamine, (D) and their copper(I) complexes, [Cu(L)(2)](+) (1a-1d) and [Cu(L)(PPh3)(2)](+) (2a-2d) have been synthesized and characterized by CHN analyses, H-1 NMR and IR and UV-Vis spectroscopy. Structures of 1a, 1b, 1c and 2a were determined by X-ray crystallography. The coordination polyhedron about the Cu-I center in the complexes is best described as a distorted tetrahedron. The dihedral angles between the least-squares planes of the chelate ligands show considerable variation from 86.1 degrees in 1a to 68.3 degrees in 1b, indicating the importance of packing forces in the crystalline environment. The UV-Vis spectra of the complexes are characterized by first metal to ligand charge transfer bands increasing in wavelength with increasing size of the ring substituents in the ligands, except for the cyclopropyl compounds (1a and 2a), in good agreement with the variation of the dihedral angles between the ligand planes. Cyclic voltammetry of the complexes indicates a quasireversible redox behavior for the complexes. The bulkier ligands (PPh3) inhibit the geometric distortion within the oxidized form and the redox potentials of complexes 2a-2d are shifted to more positive values, therefore. (C) 2009 Elsevier B.V. All rights reserved.