2,5-dihydroxybenzoic acid 2-O-β-⁴C1-glucopyranoside | 98102-34-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2,5-dihydroxybenzoic acid 2-O-β-⁴C1-glucopyranoside
• 英文别名: gentisic acid 2-O-β-glucoside；dihydroxybenzoic acid hexoside；gentisic acid 2-O-β-⁴C1-glucopyranoside；orbicularin；(2-Carboxy-4-hydroxy-phenyl)-β-D-glucopyranosid；2-β-D-Glucopyranosid der Gentisinsaeure；2-(beta-D-glucosyl)gentisic acid；5-hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acid
• CAS: 98102-34-2
• 化学式: C₁₃H₁₆O₉
• 分子量: 316.265
• InChiKey: GEZJVEGHJRPQEX-BZNQNGANSA-N

物化性质

• 沸点：
  675.4±55.0 °C(Predicted)
• 密度：
  1.686±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  157
• 氢给体数：
  6
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  2,5-dihydroxybenzoic acid 2-O-β-⁴C1-glucopyranoside 在 盐酸 作用下， 反应 3.0h， 生成 2,5-二羟基苯甲酸
  参考文献：
  名称：

  Unusual phenolic glycosides from Cotoneaster orbicularis

  摘要：

  The whole plant of Cotoneaster orbicularis contains the novel di-C-glycosylflavone 4",4"'-di-O-beta-glucopyranosyl-vicenin II, or 6.8-di-C-beta-Cellobiosylapigenin, as well as the hitherto unknown natural phenolic glucoside, gentisic acid 2-O-beta-glucopyranoside, or orbicularin. Further phenolics are protucatechuic. anisic, caffeic, p-coumaric acids, catechin, epicatechin. 2"-O-alpha-rhamnopyranosylvitexin, vitexin, rutin, isoquercetrin, hyperin and naringenin. All structures were determined by routine methods of analysis and confirmed mostly by H-1- and C-13-NMR. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(99)00598-1

文献信息

• Skin whitening agents containing glycosides
  申请人：SHISEIDO COMPANY LIMITED

  公开号：EP0649648A2

  公开（公告）日：1995-04-26

  An external preparation for skin comprising at least one of the glycosides of hydroxysalicylic acid and/or the glycosides of aliphatic esters of hydroxysalicylic acid represented by the following general formula 1; wherein R₁ represents one selected from the group consisting of a saturated hydrocarbon group and an unsaturated hydrocarbon group which have 1 to 20 carbon atoms and which may be of either a straight-chain or a branched-chain, one of R₂ and R₃ represents a sugar residue and the other hydrogen. The external preparation for skin has an excellent whitening effect and/or an excellent skin care effect.

  一种皮肤外用制剂，包含至少一种由以下通式 1 代表的羟基水杨酸苷和/或羟基水杨酸脂族酯苷； 其中 R₁ 代表选自饱和烃基和不饱和烃基组成的组中的一种，饱和烃基和不饱和烃基具有 1 至 20 个碳原子，可以是直链或支链，R₂ 和 R₃ 中的一个代表糖残基，另一个代表氢。 这种皮肤外用制剂具有极佳的美白效果和/或极佳的护肤效果。
• PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR
  申请人：Ezaki Glico Co., Ltd.

  公开号：EP1932514A1

  公开（公告）日：2008-06-18

  Provided is an external preparation for skin, comprising a phosphorylated saccharide. The phosphorylated saccharide may be an inorganic salt of a phosphorylated saccharide. The phosphorylated saccharide may be a calcium, magnesium, potassium, zinc, iron or sodium salt. Also provided is an external preparation for skin, comprising a phosphorylated saccharide and a second component, wherein the second component is selected from the group consisting of moisturizing agents, whitening components, ultraviolet absorbents, anti-inflammatory agents, cell-activating agents and antioxidants. The moisturizing agent may be ascorbic acid or an ascorbic acid derivative.

  本文提供了一种皮肤外用制剂，其中包含一种磷酸化糖。磷酸化糖可以是磷酸化糖的无机盐。磷酸化糖可以是钙、镁、钾、锌、铁或钠盐。还提供了一种皮肤外用制剂，包括磷酸化糖和第二种成分，其中第二种成分选自保湿剂、美白成分、紫外线吸收剂、消炎剂、细胞活化剂和抗氧化剂组成的组。保湿剂可以是抗坏血酸或抗坏血酸衍生物。
• External Preparation for Skin Containing a Phosphorlated Saccharide
  申请人：Tanaka Tomoko

  公开号：US20080274068A1

  公开（公告）日：2008-11-06

  Provided is an external preparation for skin, comprising a phosphorylated saccharide. The phosphorylated saccharide may be an inorganic salt of a phosphorylated saccharide. The phosphorylated saccharide may be a calcium, magnesium, potassium, zinc, iron or sodium salt. Also provided is an external preparation for skin, comprising a phosphorylated saccharide and a second component, wherein the second component is selected from the group consisting of moisturizing agents, whitening components, ultraviolet absorbents, anti-inflammatory agents, cell-activating agents and antioxidants. The moisturizing agent may be ascorbic acid or an ascorbic acid derivative.
• EXTERNAL PREPARATION FOR SKIN CONTAINING A PHOSPHORYLATED SACCHARIDE
  申请人：EZAKI GLICO CO., LTD.

  公开号：US20140023602A1

  公开（公告）日：2014-01-23

  Provided is an external preparation for skin, comprising a phosphorylated saccharide. The phosphorylated saccharide may be an inorganic salt of a phosphorylated saccharide. The phosphorylated saccharide may be a calcium, magnesium, potassium, zinc, iron or sodium salt. Also provided is an external preparation for skin, comprising a phosphorylated saccharide and a second component, wherein the second component is selected from the group consisting of moisturizing agents, whitening components, ultraviolet absorbents, anti-inflammatory agents, cell-activating agents and antioxidants. The moisturizing agent may be ascorbic acid or an ascorbic acid derivative.
• US5700784A
  申请人：——

  公开号：US5700784A

  公开（公告）日：1997-12-23