sec-Laureth-3 | 70429-16-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: sec-Laureth-3
• 英文别名: 2-[2-(2-dodecan-2-yloxyethoxy)ethoxy]ethanol
• CAS: 70429-16-2
• 化学式: C₁₈H₃₈O₄
• 分子量: 318.5
• InChiKey: AVPDLFCGPDLXES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  22
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• LIPOPHILIC DIESTERS OF CHELATING AGENT FOR INHIBITION OF ENZYME ACTIVITY
  申请人：D-Pharm Ltd.

  公开号：EP1546085A2

  公开（公告）日：2005-06-29
• EP1546085A4
  申请人：——

  公开号：EP1546085A4

  公开（公告）日：2008-03-26
• [EN] LIPOPHILIC DIESTERS OF CHELATING AGENT FOR INHIBITION OF ENZYME ACTIVITY<br/>[FR] DIESTERS LIPOPHILES D'UN AGENT CHELATEUR INHIBITEURS D'ACTIVITES ENZYMATIQUES
  申请人：DPHARM LTD

  公开号：WO2004028443A2

  公开（公告）日：2004-04-08

  The present invention relates to the use of lipophilic diesters of the chelating agent 1,2-bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) for inhibition of proteolytic activities of certain metalloproteinases and of calpain. The invention further relates to methods for preventing, treating or managing MMP-related and calpain-related diseases or disorders in mammals comprising administering to a mammal in need thereof, a pharmaceutical composition comprising a therapeutically effective amount of said lipophilic diesters of the chelating agent BAPTA.