oolongtheanine | 116310-05-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: oolongtheanine
• 英文别名: oolongtheanin；[(2R,3R)-2-[3a,5,6-trihydroxy-3-oxo-1-[(2R,3R)-3,5,7-trihydroxychroman-2-yl]-8bH-cyclopenta[b]benzofuran-8-yl]-5,7-dihydroxy-chroman-3-yl] 3,4,5-trihydroxybenzoate；[(2R,3R)-2-[3a,5,6-trihydroxy-3-oxo-1-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-8bH-cyclopenta[b][1]benzofuran-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
• CAS: 116310-05-5
• 化学式: C₃₆H₂₈O₁₇
• 分子量: 732.608
• InChiKey: BEHKEBMWHIDHDT-ZTSGSCMSSA-N

物化性质

• 沸点：
  1179.0±65.0 °C(Predicted)
• 密度：
  2.00±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  53
• 可旋转键数：
  5
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  294
• 氢给体数：
  11
• 氢受体数：
  17

反应信息

• 作为反应物：
  描述：

  oolongtheanine 在 单宁酶 、 水 作用下， 反应 0.17h， 以7 mg的产率得到desgalloyl oolongtheanin
  参考文献：
  名称：

  Hashimoto, Fumio; Nonaka, Gen-Ichiro; Nishioka, Itsuo, Chemical and pharmaceutical bulletin, 1988, vol. 36, # 5, p. 1676 - 1684

  摘要：

  DOI：
• 作为产物：
  描述：

  (-)-表没食子儿茶素没食子酸酯 、 (-)-表没食子儿茶素 在 碳酸氢钠 、 potassium hexacyanoferrate(III) 作用下， 以 水 为溶剂， 反应 1.0h， 以57 mg的产率得到theasinensin A
  参考文献：
  名称：

  Hashimoto, Fumio; Nonaka, Gen-Ichiro; Nishioka, Itsuo, Chemical and pharmaceutical bulletin, 1988, vol. 36, # 5, p. 1676 - 1684

  摘要：

  DOI：

文献信息

• FOOD PRODUCTS ENRICHED WITH METHYLXANTHINES
  申请人：Berry Mark John

  公开号：US20110318474A1

  公开（公告）日：2011-12-29

  A food product enriched with one or more methylxanthines is provided. The food product comprises a total amount of from 100 to 3000 milligram of methylxanthines per unit amount of the food product, and further comprises a polymeric polyphenol compound that has a molecular weight equal to or above 500 gram per mole and which is complexed with the one or more methylxanthines, wherein the weight ratio of the polymeric polyphenol compound to the one or more methylxanthines is from 10:1 to 1:10 A method for the production of such food products is also provided.

  提供了一种富含一种或多种甲基黄嘌呤的食品产品。该食品产品每单位食品产品含有100至3000毫克甲基黄嘌呤的总量，并进一步包含与一种或多种甲基黄嘌呤形成复合物的聚合物多酚化合物，其中聚合物多酚化合物的分子量等于或高于500克/摩尔，聚合物多酚化合物与一种或多种甲基黄嘌呤的重量比为10:1至1:10。还提供了一种生产此类食品产品的方法。
• Novel compound having inhibitory effect on lipase
  申请人：Nakai Masaaki

  公开号：US20110118344A1

  公开（公告）日：2011-05-19

  This invention provides, a novel polyphenol compound having lipase inhibitory activity derived from tealeaves, a process for the preparation of the compound, and foods and/or beverages and pharmaceutical drugs containing the compound. Particularly, this invention provides a novel dimer compound of formula: obtained by oxidative polymerization of epigallocatechin-3-O-gallate, a main catechin component of oolong tea, with a tealeaf enzyme (polyphenol oxidase), as well as foods and/or beverages and pharmaceutical compositions containing said novel compound which suppress absorption of dietary lipids and suppresses increase of blood triglyceride.

  本发明提供了一种从茶叶中提取的具有抑制脂肪酶活性的新型多酚化合物，一种制备该化合物的方法，以及包含该化合物的食品和/或饮料和药物。特别地，本发明提供了一种新型二聚体化合物，其化学式为：通过茶叶酶（多酚氧化酶）氧化聚合茶多酚中的主要儿茶素成分表沙龙茶素-3-O-没食子酸酯得到，以及包含该新型化合物的食品和/或饮料和药物组合物，其抑制膳食脂肪的吸收并抑制血液甘油三酯的增加。
• NOVEL COMPOUND HAVING INHIBITORY EFFECT ON LIPASE
  申请人：NAKAI Masaaki

  公开号：US20120329862A1

  公开（公告）日：2012-12-27

  This invention provides, a novel polyphenol compound having lipase inhibitory activity derived from tealeaves, a process for the preparation of the compound, and foods and/or beverages and pharmaceutical drugs containing the compound. Particularly, this invention provides a novel dimer compound of formula: obtained by oxidative polymerization of epigallocatechin-3-O-gallate, a main catechin component of oolong tea, with a tealeaf enzyme (polyphenol oxidase), as well as foods and/or beverages and pharmaceutical compositions containing said novel compound which suppress absorption of dietary lipids and suppresses increase of blood triglyceride.

  本发明提供了一种新型的聚酚类化合物，其具有来自茶叶的脂肪酶抑制活性，以及制备该化合物的过程，以及含有该化合物的食品和/或饮料和药物。特别地，本发明提供了一种新型的二聚体化合物，其公式为：由乌龙茶的主要儿茶素成分表油绿素-3-O-没食子酸酯与茶叶酶（聚酚氧化酶）进行氧化聚合而得到的，以及含有该新型化合物的食品和/或饮料和药物组合物，其抑制膳食脂肪的吸收并抑制血液甘油三酯的增加。
• NOVEL COMPOUND HAVING LIPASE INHIBITORY ACTIVITY
  申请人：SUNTORY LIMITED

  公开号：EP1783127A1

  公开（公告）日：2007-05-09

  This invention provides, a novel polyphenol compound having lipase inhibitory activity derived from tealeaves, a process for the preparation of the compound, and foods and/or beverages and pharmaceutical drugs containing the compound. Particularly, this invention provides a novel dimer compound of formula: obtained by oxidative polymerization of epigallocatechin-3-O-gallate, a main catechin component of oolong tea, with a tealeaf enzyme (polyphenol oxidase), as well as foods and/or beverages and pharmaceutical compositions containing said novel compound which suppress absorption of dietary lipids and suppresses increase of blood triglyceride.

  本发明提供了一种从茶叶中提取的具有脂肪酶抑制活性的新型多酚化合物、制备该化合物的工艺以及含有该化合物的食品和/或饮料及药物。 特别是，本发明提供了一种新型的式二聚化合物： 通过表没食子儿茶素-3-O-没食子酸酯（乌龙茶的主要儿茶素成分）与茶叶酶（多酚氧化酶）的氧化聚合而获得，以及含有所述新型化合物的食品和/或饮料及药物组合物，该化合物可抑制膳食脂类的吸收并抑制血液中甘油三酯的增加。
• Micellar nanocomplex
  申请人：AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

  公开号：US10052307B2

  公开（公告）日：2018-08-21

  The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent encapsulated within said micelle, where the micelle comprises a polymer-flavonoid conjugate, wherein said polymer is bonded to the B ring of said flavonoid. The micellar nanocomplex may have useful applications as a drug-delivery system.

  本发明涉及胶束纳米复合物及其形成方法。胶束纳米复合物包括胶束和封装在胶束中的药剂，其中胶束包括聚合物-黄酮类化合物共轭物，其中所述聚合物与所述黄酮类化合物的 B 环键合。胶束纳米复合物可作为药物输送系统进行有用的应用。