hydroxycyclohexadienyl radical | 155645-91-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: hydroxycyclohexadienyl radical
• 英文别名: Cyclohexadienediol；cyclohexa-2,4-diene-1,1-diol
• CAS: 155645-91-3
• 化学式: C₆H₈O₂
• 分子量: 112.128
• InChiKey: QPBQEXGQGCAOKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Process For Producing Phenol
  申请人：Wang Kun

  公开号：US20110301387A1

  公开（公告）日：2011-12-08

  Disclosed is a process for producing phenol or a substituted phenol and a co-product comprising the steps of (i) contacting a first stream comprising an alkylaromatic compound with a second stream comprising an oxygen-containing gas in the presence of a first catalyst comprising a cyclic imide under conditions to convert at least a portion of said alkylaromatic compound to an alkylaromatic hydroperoxide, (ii) producing an effluent stream comprising said cyclic imide, said alkylaromatic hydroperoxide, and said alkylaromatic compound wherein said effluent stream has an alkylaromatic hydroperoxide concentration of from 10 to 40 wt %; and (iii) contacting in a second reactor at least a portion of said effluent stream with a second catalyst to convert said alkylaromatic hydroperoxide to a product stream comprising phenol and said co-product.

  本发明公开了一种生产苯酚或取代苯酚及共生产物的方法，包括以下步骤：(i)在第一催化剂的存在下，将含有烷基芳香化合物的第一流与含有含氧气体的第二流接触，以将至少部分烷基芳香化合物转化为烷基芳香羟基过氧化物；(ii)生成包含所述第一催化剂、所述烷基芳香羟基过氧化物和所述烷基芳香化合物的流出流，其中所述流出流的烷基芳香羟基过氧化物浓度为10至40重量％；以及(iii)在第二反应器中将所述流出流的至少一部分与第二催化剂接触，以将所述烷基芳香羟基过氧化物转化为包含苯酚和所述共生产物的产品流。
• Benzene oxygenase gene
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0247600A2

  公开（公告）日：1987-12-02

  A benzene oxygenase gene which contains DNA segments Nos. I, II and III localized therein as the base (nucleotide) sequences in combination, coding for an amino acid sequence of a particular enzyme (benzene oxygenase). Transformed cells of microorganisms such as Escherichia coli capable of producing benzene oxygenase are obtained by transforming the cells of said microorganism, which are incapable of producing said enzyme,with recombinant DNA which contains the benzene oxygenase gene as defined above and a vector.

  一种苯加氧酶基因，它包含 DNA 片段 I、II 和 III，其中的碱基（核苷酸）序列组合编码特定酶（苯加氧酶）的氨基酸序列。 用含有上述苯加氧酶基因的重组 DNA 和载体转化不能产生上述酶的微生物细胞，可获得能产生苯加氧酶的大肠杆菌等微生物的转化细胞。
• Production of cells
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0250122A2

  公开（公告）日：1987-12-23

  A method of growing cells of Pseudomonas putida, preferably mutants of strains NCIB 11680 or 11767, to induce in them an enzyme capable of converting an aromatic or substituted aromatic compound to a corresponding cyclic dihydroxy compound. Suitable inducers include pyridine and substituted pyridines.

  一种培养假单胞菌（Pseudomonas putida）细胞（最好是 NCIB 11680 或 11767 菌株的突变体）的方法，以诱导它们产生一种能将芳香族化合物或取代芳香族化合物转化为相应的环状二羟基化合物的酶。 合适的诱导剂包括吡啶和取代吡啶。
• Separation of 1,2-dihydroxycyclohexa-3,5-diene compounds
  申请人：ZENECA LIMITED

  公开号：EP0379300A2

  公开（公告）日：1990-07-25

  A process for the separation of a compound comprising a 1,2-­dihydroxycyclohexa-3,5-diene ring from a medium containing it in which the compound reacts with a phenylboronate ion to form a phenylboronate ester which is insoluble in the medium. Novel phenylboronate esters formed during the separation process are also claimed.

  一种将包含 1，2-二羟基环己-3，5-二烯环的化合物从含有该化合物的介质中分离出来的工艺，在该工艺中，该化合物与苯硼酸离子反应生成不溶于介质的苯硼酸酯。在分离过程中形成的新型苯硼酸酯也在权利要求之列。
• Biological production of novel cyclohexadienediols
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0400779A1

  公开（公告）日：1990-12-05

  Meta-hydroxyphenylacetylenes are produced from phenyl-substituted ketal or acetal precursors. Using biotransformation processes, these precursors serve as substrates that are converted to cis-dihydrodiol intermediates. The cis-dihydrodiols can be converted chemically to the corresponding meta-substituted compounds, e.g., meta-substituted phenols, and then to m-hydroxyphenylacetylene, which is an intermediate needed to produce acetylene-terminated resins. The biotransformation step employs arene-2,3-dioxygenase in intra- or extra- cellular form.

  间羟基苯乙炔是从苯基取代的缩酮或缩醛前体中生产出来的。通过生物转化过程，这些前体可作为底物转化为顺式二氢二醇中间体。顺式二氢二醇可以通过化学反应转化为相应的元代化合物，例如元代苯酚，然后转化为间羟基苯乙炔，这是生产乙炔端树脂所需的中间体。生物转化步骤采用细胞内或细胞外形式的炔-2,3-二氧 化酶。