Ethyl 2-bromo-4,9-dioxobicyclo[3.3.1]non-2-ene-1-carboxylate | 515857-08-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Ethyl 2-bromo-4,9-dioxobicyclo[3.3.1]non-2-ene-1-carboxylate
• 英文别名: ethyl 2-bromo-4,9-dioxobicyclo[3.3.1]non-2-ene-1-carboxylate
• CAS: 515857-08-6
• 化学式: C₁₂H₁₃BrO₄
• 分子量: 301.137
• InChiKey: HXQSTUICOBIPOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  60.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  烯丙醇 、 Ethyl 2-bromo-4,9-dioxobicyclo[3.3.1]non-2-ene-1-carboxylate 在 sodium 作用下， 以 甲苯 为溶剂， 反应 8.0h， 生成
  参考文献：
  名称：

  Synthesis of a model system for the preparation of phloroglucinol containing natural products

  摘要：

  A model system for the synthesis of phloroglucinol containing natural products was synthesized. Key steps include a manganic acetate-mediated cyclization and the facile conversion of an alkene into a beta-bromoenone. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.03.001
• 作为产物：
  描述：

  9-oxo-bicyclo[3.3.1]non-3-ene-1-carboxylic acid ethyl ester 在 N-溴代丁二酰亚胺(NBS) 、 偶氮二异丁腈 作用下， 以 四氯化碳 为溶剂， 反应 3.0h， 生成 Ethyl 2-bromo-4,9-dioxobicyclo[3.3.1]non-2-ene-1-carboxylate
  参考文献：
  名称：

  Synthesis of a model system for the preparation of phloroglucinol containing natural products

  摘要：

  A model system for the synthesis of phloroglucinol containing natural products was synthesized. Key steps include a manganic acetate-mediated cyclization and the facile conversion of an alkene into a beta-bromoenone. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2003.03.001

文献信息

• Synthesis of a model system for the preparation of phloroglucinol containing natural products
  作者：George A Kraus、Elena Dneprovskaia、Tuan H Nguyen、Insik Jeon

  DOI：10.1016/j.tet.2003.03.001

  日期：2003.11

  A model system for the synthesis of phloroglucinol containing natural products was synthesized. Key steps include a manganic acetate-mediated cyclization and the facile conversion of an alkene into a beta-bromoenone. (C) 2003 Elsevier Ltd. All rights reserved.