quercitrin | 865688-88-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 英文名称: quercitrin
• 英文别名: quercetin 3‐O‐α‐L‐rhamnoside；quercetin 3-O-β-D-glucuronopyranoside；quercetin 3-O-α-L-rhamnopyranoside；quercetin 3-O-α-rhamnopyranoside；quercetin 3-O-α-L-rhamnoside；quercetin 3-O-α-rhamnoside；2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-chromen-4-one；2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
• CAS: 865688-88-6
• 化学式: C₂₁H₂₀O₁₁
• 分子量: 448.383
• InChiKey: OXGUCUVFOIWWQJ-JHPRLSDPSA-N

物化性质

• 沸点：
  814.0±65.0 °C(Predicted)
• 密度：
  1.79±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  32
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  186
• 氢给体数：
  7
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  quercitrin 在 hesperidinase 作用下， 生成 D-rhamnose 、 槲皮素
  参考文献：
  名称：

  Studies on antihemorrhagic substances in herbs classified as hemostatics in Chinese medicine. V. On antihemorrhagic principle in Biota orientalis (L.) Endl.

  摘要：

  本文介绍了通过结合使用 Sephadex LH-20 和硅胶柱色谱法，从东方树（Biota orientalis (L.) ENDL.）（濯缨草科）植物中分离出一种止血原理，并将其鉴定为槲皮素。(铜雀花科植物）中的一种止血成分，并将其鉴定为槲皮素。

  DOI：

  10.1248/cpb.33.206

文献信息

• Anti-inflammatory cranberry flavonol extract preparations
  申请人：Vorsa Nicholi

  公开号：US20060088610A1

  公开（公告）日：2006-04-27

  The present invention is directed to extracts of cranberries ( Vaccinium macrocarpon ) comprising either mixed flavonols that are substantially free of anthocyanins and proanthocyanidins or a purified cranberry flavonol compound, including myricetin-3-β-xylopyranoside, quercetin-3-β-glucoside, quercetin-3-α-arabinopyranoside, 3′-methoxyquercetin-3-α-xylopyranoside, quercetin-3-O-(6″-p-coumaroyl)-β-galactoside, and quercetin-3-O-(6″-benzoyl)-β-galactoside. The present invention also embodies the use of those extracts, as well as extracts comprising the cranberry flavonol compound quercetin-3-α-arabinofuranoside, for the treatment of inflammatory disorders. Pharmaceutical, food, dietary supplement, and cosmetic compositions utilizing the extracts or compounds of the present invention are also recited.

  本发明涉及蔓越莓（Vaccinium macrocarpon）的提取物。 蔓越莓 )的提取物，该提取物包含基本不含花青素和原花青素的混合黄酮醇或纯化的蔓越莓黄酮醇化合物，包括杨梅素-3-β-木吡喃糖苷槲皮素-3-β-葡萄糖苷、槲皮素-3-α-阿拉伯吡喃糖苷、3′-甲氧基槲皮素-3-α-木吡喃糖苷、槲皮素-3-O-(6″-对香豆酰基)-β-半乳糖苷和槲皮素-3-O-(6″-苯甲酰基)-β-半乳糖苷。本发明还包括使用这些提取物以及包含蔓越莓黄酮醇化合物槲皮素-3-α-阿拉伯呋喃糖苷的提取物来治疗炎症性疾病。此外，还叙述了利用本发明提取物或化合物的药物、食品、膳食补充剂和化妆品组合物。
• USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY
  申请人：Stewart Colin

  公开号：US20100267653A1

  公开（公告）日：2010-10-21

  The invention provides coumarin compounds, in particular glycosidic coumarin compounds, useful in the treatment of dermatophyte fungal infections.
• MAPLE TREE-DERIVED PRODUCTS AND USES THEREOF
  申请人：Barbeau Julie

  公开号：US20130310332A1

  公开（公告）日：2013-11-21

  The present document describes a neutraceutical, cosmeceuticals, functional food, pharmaceutical, food ingredient, and non-food ingredient compositions comprising sugar maple extract, essential oil compositions comprising oil extracted from an Acer tree, sweetening compositions containing sugar extracted from maple tree leaves, food ingredients comprising maple tree extract, cosmetic composition comprising maple tree extracts, infusion compositions prepared from maple tree leaves, maple roots, maple wood, maple stems of leaves and samara, and stems/twigs as well as compounds isolated from sugar maple biomass and the methods of extracting the same.
• US7270837B2
  申请人：——

  公开号：US7270837B2

  公开（公告）日：2007-09-18
• [EN] USE OF COUMARIN DERIVATIVES IN ANTIFUNGAL THERAPY<br/>[FR] COMPOSÉS ET LEUR UTILISATION
  申请人：NOVABIOTICS LTD

  公开号：WO2007141513A1

  公开（公告）日：2007-12-13

  [EN] The invention provides coumarin compounds, in particular glycosidic coumarin compounds, useful in the treatment of dermatophyte fungal infections.
  [FR] La présente invention concerne des composés de coumarine, en particulier des composés de coumarine glycosidique, utiles dans le traitement d'infections fongiques par des dermatophytes.