3,6-dimethyl 9-(phenylsulfonyl)-9H-carbazole-3,6-dicarboxylate | 856252-08-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 3,6-dimethyl 9-(phenylsulfonyl)-9H-carbazole-3,6-dicarboxylate
• 英文别名: Dimethyl 9-(benzenesulfonyl)carbazole-3,6-dicarboxylate；dimethyl 9-(benzenesulfonyl)carbazole-3,6-dicarboxylate
• CAS: 856252-08-9
• 化学式: C₂₂H₁₇NO₆S
• 分子量: 423.446
• InChiKey: CYKISJHCRTZNST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  100
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  (3E,4E)-dimethyl 3,3'-(2,5-dimethyl-1-(phenylsulfonyl)-1H-pyrrole-3,4-diyl)diacrylate 、 N,N-二甲基甲酰胺二甲基缩醛 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 以55%的产率得到3,6-dimethyl 9-(phenylsulfonyl)-9H-carbazole-3,6-dicarboxylate
  参考文献：
  名称：

  Synthesis of substituted carbazoles via electrocyclization of in situ generated enamines from 1-phenylsulfonyl-2/(3)-methyl-3/(2)-vinylindoles and DMF·DMA/DMA·DMA

  摘要：

  Interaction of 2/(3)-methyl-3/(2)-vinylindoles and DMF center dot DMA/DMA center dot DMA at 110 degrees C led to the in situ generation of enamines, which on concurrent electrocyclization followed by subsequent aromatization afforded substituted carbazoles. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.03.010

文献信息

• Synthesis of substituted carbazoles via electrocyclization of in situ generated enamines from 1-phenylsulfonyl-2/(3)-methyl-3/(2)-vinylindoles and DMF·DMA/DMA·DMA
  作者：Radhakrishnan Sureshbabu、Ramalingam Balamurugan、Arasambattu K. Mohanakrishnan

  DOI：10.1016/j.tet.2009.03.010

  日期：2009.5

  Interaction of 2/(3)-methyl-3/(2)-vinylindoles and DMF center dot DMA/DMA center dot DMA at 110 degrees C led to the in situ generation of enamines, which on concurrent electrocyclization followed by subsequent aromatization afforded substituted carbazoles. (C) 2009 Elsevier Ltd. All rights reserved.