(6S*,9aS*)-5,6-dihydro-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxo-1,4,6,8-decatetraenyl]-6-hydroxymethyl-9a-methyl-2H-furo[3,2-g]benzopyran-2-9(9H)-dione | 371163-96-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (6S*,9aS*)-5,6-dihydro-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxo-1,4,6,8-decatetraenyl]-6-hydroxymethyl-9a-methyl-2H-furo[3,2-g]benzopyran-2-9(9H)-dione
• 英文别名: epicocconone；(6S,9aS)-6-(hydroxymethyl)-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxodeca-1,4,6,8-tetraenyl]-9a-methyl-5,6-dihydrofuro[3,2-g]isochromene-2,9-dione
• CAS: 371163-96-1
• 化学式: C₂₃H₂₂O₇
• 分子量: 410.423
• InChiKey: JKMBMIMLVFMXRW-LYYFRFARSA-N

物化性质

• 比旋光度：
  D25 +110° (c = 0.009 in acetonitrile)

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  30
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  110
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  正丁胺 、 (6S*,9aS*)-5,6-dihydro-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxo-1,4,6,8-decatetraenyl]-6-hydroxymethyl-9a-methyl-2H-furo[3,2-g]benzopyran-2-9(9H)-dione 以 乙腈 为溶剂， 以17%的产率得到rel-(S,Z)-6-((butylamino)methylene)-5-((S)-2,3-dihydroxypropyl)-3-((1Z,4E,6E,8E)-1-hydroxy-3-oxodeca-1,4,6,8-tetraenyl)-7a-methylbenzofuran-2,7(6H,7aH)-dione
  参考文献：
  名称：

  Mechanism of Reversible Fluorescent Staining of Protein with Epicocconone

  摘要：

  [GRAPHICS]Epicocconone is the active ingredient in Deep Purple Total Protein Stain and responsible for the apparent noncovalent staining of proteins in polyacrylamide gel and electroblots. Reaction of epicocconone with amines has shown that epicocconone reacts reversibly with primary amines to produce a highly fluorescent enamine that is readily hydrolyzed by base or strong acid such as in conditions used in postelectrophoretic analysis such as peptide mass fingerprinting or Edman degradation.

  DOI：

  10.1021/ol050665b

文献信息

• [EN] PROCESS FOR SYNTHESIZING EPICOCCONONE ANALOGS<br/>[FR] PROCÉDÉ POUR SYNTHÉTISER DES ANALOGUES D'ÉPICOCCONONE
  申请人：UNIV ROUEN

  公开号：WO2011051225A1

  公开（公告）日：2011-05-05

  The present invention relates to a process for the total synthesis of epicocconone analogs of formula (I): The invention also relates to novel epicocconone analogs.

  本发明涉及一种用于合成公式（I）的epicocconone类似物的全合成过程。该发明还涉及新的epicocconone类似物。
• PROCESS FOR SYNTHESIZING EPICCONONE ANALOGS
  申请人：Franck Xavier

  公开号：US20120214194A1

  公开（公告）日：2012-08-23

  The present invention relates to a process for the total synthesis of epicocconone analogs of formula (I): The invention also relates to novel epicocconone analogs.

  本发明涉及一种用于全合成式(I)的epicocconone类似物的过程，同时也涉及新的epicocconone类似物。
• PROCESS FOR SYNTHESIZING EPICOCCONONE ANALOGS
  申请人：Universite de Rouen

  公开号：EP2493869B1

  公开（公告）日：2014-10-22
• Fluorescent Compounds
  申请人：Bell Livingston Philip John

  公开号：US20080085993A1

  公开（公告）日：2008-04-10

  Fluorescent dye compounds of formula (I) are disclosed. These compounds are useful as they interact with organic compounds in a manner such that excitation with certain wavelengths of light results in fluorescent emission. Detection and/or monitoring of the fluorescence provides a means for the detection or quantification of organic compounds when bound to these fluorescent dye compounds. Formula (I), wherein: each of R, R′ and R″ is a hydrogen atom, halogen atom or a straight or branched C 1-20 alkyl, alkenyl or alkynl group optionally substituted with one or more halogen, hydroxyl, and/or oxy group; rings A, B and C optionally include one or more double bonds; rings B and C are optionally substituted with one or more halogen atoms.
• DEVICE, METHOD AND APPARATUS FOR ANALYZING SKIN AND HAIR
  申请人：Hanes Robert Eugene

  公开号：US20100105102A1

  公开（公告）日：2010-04-29

  The present invention includes compositions, methods, and systems for the analysis of skin and hair conditions. The system includes a method and apparatus for analyzing skin and hair samples by taking a sample, identifying desired components of the sample, obtaining an image electronically, storing the image, and analyzing the image using analysis software.