methyl 4,6-di-O-methyl-D-glucopyranoside | 82262-93-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 4,6-di-O-methyl-D-glucopyranoside
• 英文别名: (3R,4R,5S,6R)-2,5-dimethoxy-6-(methoxymethyl)oxane-3,4-diol
• CAS: 82262-93-9
• 化学式: C₉H₁₈O₆
• 分子量: 222.238
• InChiKey: UKSOTSKNRMTYIO-VARJHODCSA-N

物化性质

• 沸点：
  344.5±42.0 °C(Predicted)
• 密度：
  1.22±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.26
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  77.38
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  (2S,3R,4S,5R)-2-[(2S,3R,4R,5R,6R)-2-[(2S,3R,4S,5R,6R)-2-[(2R,3R,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(1R,2S,4S,5'R,6R,7S,8R,9S,12S,13S,16S,18S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-yl]oxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxyoxane-3,4,5-triol 生成 methyl 4,6-di-O-methyl-D-glucopyranoside
  参考文献：
  名称：

  NAKANO, KIMIKO;MATSUDA, EMI;TSURUMI, KAORI;YAMASAKI, TOKUSHI;MURAKAMI, KO+, PHYTOCHEMISTRY, 27,(1988) N 10, C. 3235-3239

  摘要：

  DOI：

文献信息

• Studies on the constituents of Solanum plants. V. The constituents of S. lyratum Thunb. II.
  作者：KOTARO MURAKAMI、HISATAKA EZIMA、YOSHIHISA TAKAISHI、YOSHIO TAKEDA、TETSURO FUJITA、AKIHIKO SATO、YOKO NAGAYAMA、TOSHIHIRO NOHARA

  DOI：10.1248/cpb.33.67

  日期：——

  Two new steroidal alkaloid glycosides, tentatively named SL-c (1) and SL-d (2), were obtained from the stems of Solanum lyratum THUNB. The chemical structures of 1 and 2 were characterized respectively as β-lycotrioside and β-lycotetraoside, both having a mixture of (25ζ)-solanidan-3β, 23β-diol and (25ζ)-Δ5-solaniden-3β, 23β-diol as the aglycone moiety. These compounds markedly inhibited the growth of a human cervical cancer cell line, JTC-26.

  从Solanum lyratum THUNB的茎中获得了两种新的甾体生物碱苷，暂命名为SL-c (1)和SL-d (2)。 1和2的化学结构分别为β-lycotrioside和β-lycotetraoside，均具有(25ζ)-solaniden-3β, 23β-diol和(25ζ)-Δ5-solaniden-3β, 23β-diol的混合物：糖苷配基部分。这些化合物显着抑制人宫颈癌细胞系 JTC-26 的生长。
• Isolation and characterization of a furostanol glycoside from fenugreek
  作者：Roland Hardman、Junzo Kosugi、Robert T. Parfitt

  DOI：10.1016/0031-9422(80)87046-4

  日期：1980.1

  Abstract From the seed of fenugreek, a new glycoside has been isolated and shown to have the structure, (25 S )- 22 - O - methyl-5α-furostan-3β,22,26-triol 3- O -α-rhamnopyranosyl(1→2)[-β- d -glucopyranosyl (1→3)]-β- d - glucopyranoside-26- O -β- d -glucopyranoside.

  摘要 从胡芦巴种子中分离出一种新的糖苷，其结构为 (25 S )- 22 - O -methyl-5α-furostan-3β,22,26-triol 3-O -α-rhamnopyranosyl( 1→2)[-β-d-吡喃葡萄糖基(1→3)]-β-d-吡喃葡萄糖苷-26-O-β-d-吡喃葡萄糖苷。
• The steroidal glycosides of the flowers of Yucca gloriosa
  作者：Kimiko Nakano、Emi Matsuda、Kaori Tsurumi、Tokushi Yamasaki、Kotaro Murakami、Yoshihisa Takaishi、Toshiaki Tomimatsu

  DOI：10.1016/0031-9422(88)80033-5

  日期：1988.1

  Abstract Four steroidal compounds were isolated from the fresh flowers of Yucca gloriosa and their structures were elucidated as tigogenin 3-O-β- d -xylopyranosyl-β-lycotetraoside, gitogenin 3-O-β- d -xylopyranosyl-β-lycotetraoside, gitogenin 3-O-α- l -rhamnopyranosyl-β-lycotetraoside and proto-type of gitogenin 3-O-β- d -xylopyranosyl-β-lycotetraoside, on the basis of physical and chemical investigations

  摘要 从兰兰鲜花中分离得到4种甾体化合物，并阐明了其结构为：tigogenin 3-O-β-d-吡喃木糖基-β-lycotetraoside、gitogenin 3-O-β-d-xylopyranosyl-β-lycotetraoside、gitogenin 3-O-α-l -rhamnopyranosyl-β-lycotetraoside 和 gitogenin 3-O-β-d -xylopyranosyl-β-lycotetraoside 的原型，基于物理和化学研究。
• Watanabe, Yoshiaki; Sanada, Shuichi; Ida, Yoshiteru, Chemical and pharmaceutical bulletin, 1983, vol. 31, # 6, p. 1980 - 1990
  作者：Watanabe, Yoshiaki、Sanada, Shuichi、Ida, Yoshiteru、Shoji, Junzo

  DOI：——

  日期：——
• Melongoside L and melongoside M, steroidal saponins from Solanum melongena seeds
  作者：Pavel K. Kintia、Stepan A. Shvets

  DOI：10.1016/s0031-9422(00)80843-2

  日期：1985.1