diethanolamine | 57058-68-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: diethanolamine
• 英文别名: diethoxy monoamine；Diethoxyamine；(ethoxyamino)oxyethane
• CAS: 57058-68-1
• 化学式: C₄H₁₁NO₂
• 分子量: 105.137
• InChiKey: VXMQKONTARQGPP-UHFFFAOYSA-N

物化性质

• 沸点：
  77.0±23.0 °C(Predicted)
• 密度：
  0.905±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  7
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  30.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  diethanolamine 、 (3-氯丙基)二乙氧基(乙基)锗烷 在 (C₂H₅)3N 作用下， 以 乙醇 为溶剂， 以57%的产率得到1-ethyl-2-carbagermatrane
  参考文献：
  名称：

  Gar, T. K.; Khromova, N. Yu.; Tandura, S. N., Journal of general chemistry of the USSR, 1982, vol. 52, p. 545 - 550

  摘要：

  DOI：

文献信息

• Topical siloxane sunscreen compositions having enhanced performance and
  申请人：Special Advanced Biomaterials, Inc.

  公开号：US05686065A1

  公开（公告）日：1997-11-11

  Methods and compositions that provide for the long-term adhesion and slow-release of various bioactive agents on the surface of human skin utilize siloxane bridging agents activated for reaction with the skin surface which bind the bioactive agent to the skin surface. Since the topical agent remains bound to the continuously renewing epidermis, safety is enhanced for many bioactive agents. Slight modifications of the siloxane bridging compounds or bioactive agents allows for more or less adhesion to the skin, controlling the degree of release of the agent. Skin treatments according to the invention can provide enhanced repellency to microorganisms, insect bites, sun, water, poison ivy/oak, and other skin irritants, and other effects such as artificial skin coloring and administration of topical drugs, among others.

  提供长期粘附和缓慢释放各种生物活性剂在人体皮肤表面的方法和组合物利用硅氧烷桥联剂激活与皮肤表面反应，将生物活性剂结合到皮肤表面。由于局部药剂仍然与不断更新的表皮结合，对许多生物活性剂增强了安全性。对硅氧烷桥联化合物或生物活性剂进行轻微修改，可以实现更多或更少地粘附到皮肤，控制药剂的释放程度。根据本发明的皮肤治疗可以提供对微生物、昆虫叮咬、阳光、水、毒葛/毒橡树和其他皮肤刺激物的增强驱避力，以及其他效果，如人工皮肤着色和局部药物给药等。
• Bioactive topical siloxane compositions having enhanced performance and
  申请人：Special Advanced Biomaterials, Inc.

  公开号：US05891914A1

  公开（公告）日：1999-04-06

  Methods and compositions that provide for the long-term adhesion and slow-release of various bioactive agents on the surface of human skin utilize siloxane bridging agents activated for reaction with the skin surface which bind the bioactive agent to the skin surface. Since the topical agent remains bound to the continuously renewing epidermis, safety is enhanced for many bioactive agents. Slight modifications of the siloxane bridging compounds or bioactive agents allows for more or less adhesion to the skin, controlling the degree of release of the agent. Skin treatments according to the invention can provide enhanced repellency to microorganisms, insect bites, sun, water, poison ivy/oak, and other skin irritants, and other effects such as artificial skin coloring and administration of topical drugs, among others.

  本发明提供了长期粘附和缓慢释放各种生物活性剂在人体皮肤表面的方法和组合物，利用硅氧烷桥联剂与皮肤表面反应激活，将生物活性剂与皮肤表面结合。由于局部制剂仍然与不断更新的表皮结合，许多生物活性剂的安全性得到了提高。硅氧烷桥联化合物或生物活性剂的轻微修改允许更多或更少地粘附于皮肤，控制剂的释放程度。根据本发明的皮肤治疗可以提供增强的抗微生物、昆虫叮咬、阳光、水、毒葛/橡树等皮肤刺激剂的排斥作用，以及人工皮肤着色和局部药物管理等其他效果。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Fe: Org.Verb.A5, 5.1.5.11, page 53 - 64
  作者：

  DOI：——

  日期：——
• Boev, V. I.; Osipenko, A. S.; Dombrovskii, A. V., Zhurnal Obshchei Khimii, 1977, vol. 47, p. 393 - 398
  作者：Boev, V. I.、Osipenko, A. S.、Dombrovskii, A. V.

  DOI：——

  日期：——
• Gar, T. K.; Khromova, N. Yu.; Tandura, S. N., Journal of general chemistry of the USSR, 1982, vol. 52, p. 545 - 550
  作者：Gar, T. K.、Khromova, N. Yu.、Tandura, S. N.、Nosova, V. M.、Kisin, A. V.、Mironov, V. F.

  DOI：——

  日期：——