N-dodecyl-p-anisamide | 1854-15-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-dodecyl-p-anisamide
• 英文别名: N-dodecyl-4-methoxybenzamide
• CAS: 1854-15-5
• 化学式: C₂₀H₃₃NO₂
• 分子量: 319.488
• InChiKey: KVEZPQNBMSQMQU-UHFFFAOYSA-N

物化性质

• 沸点：
  462.7±28.0 °C(Predicted)
• 密度：
  0.952±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  23
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  十二烷基伯胺 、 大茴香酸 在 1,3-diazabicyclo[5.4.0]-undec-7-ene 、 1,1,2,2-四氟-2-(1,1,2,2-四氟乙氧基)乙烷磺酰基氟化物 作用下， 以 二氯甲烷 为溶剂， 反应 37.0h， 以73%的产率得到N-dodecyl-p-anisamide
  参考文献：
  名称：

  5 H -3-氧杂-八氟戊烷磺酰氟：一种新型的高效酯化，酰胺化和脱水缩合剂

  摘要：

  5 H -3-氧杂八氟戊磺酰氟（HCF 2 CF 2 OCF 2 CF 2 SO 2 F）作为新型高效的缩合剂用于羧酸与醇的酯化和羧酸与胺的酰胺化报道了1，3-二氮杂双环[5.4.0]-十一碳-7-烯（DBU）。HCF 2 CF 2 OCF 2 CF 2 SO 2 F不能用作羧酸脱水的缩合剂，但是HCF 2 CF 2 OCF 2 CF 2 SO 2 F /（CH3）3 SiCN系统可以介导某些芳香族羧酸的脱水反应。

  DOI：

  10.1016/j.tetlet.2009.03.102

文献信息

• Facile preparation of amides from carboxylic acids and amines with ion-supported Ph3P
  作者：Yuhsuke Kawagoe、Katsuhiko Moriyama、Hideo Togo

  DOI：10.1016/j.tet.2013.03.021

  日期：2013.5

  rimethylammonium bromide (IS-Ph3P), could be used for the facile amidation of a wide range of carboxylic acids with amines in the presence of bromotrichloromethane to provide the corresponding amides in good yields. In the present reaction, the desired amides were obtained in good yields with high purity by simple extraction of the reaction mixture with diethyl ether or chloroform and subsequent removal

  离子负载的Ph 3 P，4-（二苯基膦基）苄基三甲基溴化铵（IS-Ph 3 P）可用于在溴三氯甲烷存在下将多种羧酸与胺轻松酰胺化，从而提供相应的酰胺产量。在本反应中，通过用二乙醚或氯仿简单萃取反应混合物，然后从萃取物中除去溶剂，以高收率和高纯度获得所需酰胺。另外，在本还原缩合反应中作为IS-Ph 3 P的副产物的离子担载的Ph 3 PO（IS-Ph 3 PO）被高收率回收，可以还原为IS-Ph 3。P用于在相同的酰胺化羧酸中重复使用。
• Application of phase-vanishing method with CO gas evolution to carbonylation reactions
  作者：Yusuke Adachi、Hiroshi Matsubara

  DOI：10.1016/j.jfluchem.2018.10.006

  日期：2018.12

  Although carbon monoxide (CO) is considered a practical source of the carbonyl functionality in various compounds, handling CO gas is difficult. The phase-vanishing (PV) method, using highly fluorinated solvents as the phase screen, was thus employed, in which CO was evolved for use in organic synthesis. An H-shaped reactor bearing two reaction chambers was employed. In the first chamber, CO was efficiently

  尽管一氧化碳（CO）被认为是各种化合物中羰基官能度的实用来源，但处理CO气体却很困难。因此，采用了使用高度氟化的溶剂作为相筛的消失相（PV）方法，其中析出了CO以用于有机合成。使用带有两个反应室的H形反应器。在第一个反应室中，在PV条件下由硫酸和甲酸铵有效地产生了CO，然后在第二个反应室中以钯催化的羰基化反应消耗了CO，得到了所需的产物。使用该光伏系统可轻松安全地生成有害的CO气体，并将其用于有机合成中。
• Ester Aminolysis in the Presence of Alkylammonium Carboxylate Reversed Micelles. A Mechanistic Study
  作者：Omar A. El Seoud、Rita C. Vieira、Luzia P. Novaki

  DOI：10.1246/bcsj.60.1163

  日期：1987.3

  A study of ester aminolysis in the presence of dodecylammonium carboxylate reversed micelles showed that the catalytic role of the surfactant head-anion (general base) was concentration independent. The presence of cosolubilized water in the micelle did not lead to detectable ester hydrolysis.

  在十二烷基羧酸铵反胶束存在下酯氨解的研究表明，表面活性剂头阴离子（一般碱）的催化作用与浓度无关。胶束中共溶水的存在不会导致可检测到的酯水解。
• Thermal transfer recording system
  申请人：——

  公开号：US20010043239A1

  公开（公告）日：2001-11-22

  There is described a thermal recording system which utilizes a donor element comprising a substrate and a thermal transfer material layer having a dye-containing phase which is amorphous and wherein the dye or dyes present in the amorphous phase form a continuous film. Imagewise heating of the medium transfers portions of the transfer layer to a receiver sheet, thus forming an image. The transfer layer may also include a non-dye phase comprising a thermal solvent. During the heating of the donor element, the crystalline thermal solvent melts and dissolves or liquefies at least a portion of the dye-containing phase, thereby lowering the temperature at which transfer of the transfer layer occurs.

  描述了一种热记录系统，其利用包括基板和具有含有染料的非晶相的热转移材料层的给体元件，其中在非晶相中存在的染料形成连续的薄膜。对介质进行成像加热，将转移层的部分转移到接收纸张上，从而形成图像。转移层还可以包括包含热溶剂的非染料相。在加热给体元件时，晶体热溶剂熔化并溶解或液化至少部分含有染料的相，从而降低转移层转移温度。
• Thermal transfer recording system having an amorphous dye phase
  申请人：Polaroid Corporation

  公开号：EP1493593A1

  公开（公告）日：2005-01-05

  There is described a thermal recording system which utilizes a donor element comprising a substrate and a thermal transfer material layer having a dye-containing phase which is amorphous and wherein the dye or dyes present in the amorphous phase form a continuous film. Imagewise heating of the medium transfers portions of the transfer layer to a receiver sheet, thus forming an image. The transfer layer may also include a non-dye phase comprising a thermal solvent. During heating of the donor element, the crystalline thermal solvent melts and dissolves or liquefies at least a portion of the dye-containing phase, thereby lowering the temperature at which transfer of the transfer layer occurs.

  本文描述了一种热记录系统，该系统利用一个由基片和热转印材料层组成的供体元件，热转印材料层具有无定形的含染料相，其中存在于无定形相中的染料形成连续的薄膜。介质的图像加热将转印层的部分转移到接收片上，从而形成图像。转移层还可包括由热溶剂组成的非染料相。在加热供体元件的过程中，结晶热溶剂会熔化并溶解或液化至少一部分含染料相，从而降低转移层发生转移的温度。