1-n-Propoxy-2-n-butoxyaethan | 18854-58-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-n-Propoxy-2-n-butoxyaethan
• 英文别名: 2-n-Propoxy-1-butoxyethan；1-Propoxy-2-butoxyaethan；1-(2-propoxy-ethoxy)-butane；1-(2-Propoxyethoxy)butane
• CAS: 18854-58-5
• 化学式: C₉H₂₀O₂
• 分子量: 160.257
• InChiKey: ZCBZQEYJWBUONO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• POLYOL ETHERS AND PROCESS FOR MAKING THEM
  申请人：Tulchinsky Michael L.

  公开号：US20100048940A1

  公开（公告）日：2010-02-25

  New polyol ether compounds and a process for their preparation. The process comprises reacting a polyol, a carbonyl compound, and hydrogen in the presence of hydrogenation catalyst, to provide the polyol ether. The molar ratio of polyol to carbonyl compound in the process is greater than 5:1.

  新的聚醚醇化合物及其制备方法。该方法包括在氢化催化剂存在下，使聚醇、羰基化合物和氢发生反应，从而提供聚醚醇。在该过程中，聚醇与羰基化合物的摩尔比大于5:1。
• Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient
  申请人：——

  公开号：US20030216381A1

  公开（公告）日：2003-11-20

  A carboxylic acid derivative of formula (1) 1 wherein R 1 is COOH, COOR 6 etc.; A is alkylene etc.; R 2 is alkyl, alkenyl, alkynyl etc.; B is carbocyclic ring or heterocyclic ring; R 4 is alkyl, cycloalkyl etc.; R 6 is carbocyclic ring or heterocyclic ring; or non-toxic salts thereof, a process for the preparation thereof and a pharmaceutical agent comprising the same as active ingredient. The compound of the formula (I) can bind to Prostaglandin E 2 receptors, especially, EP 3 receptor and/or EP 4 receptor and show the antagonizing activity, and useful for the prevention and/or treatment of disease, for example, pain, allergy, Alzheimer's disease, cancer.

  化学式（1）1的羧酸衍生物，其中R1是COOH，COOR6等；A是烷基等；R2是烷基，烯基，炔基等；B是碳环或杂环；R4是烷基，环烷基等；R6是碳环或杂环；或其无毒盐，以其为活性成分的制备方法和含有其的药物制剂。化合物的化学式（I）可以结合到前列腺素E2受体，特别是EP3受体和/或EP4受体，并显示拮抗活性，对于预防和/或治疗疾病，例如疼痛，过敏，阿尔茨海默病，癌症等非常有用。
• Benzoic acid derivatives and pharmaceutical agents comprising the same as active ingredient
  申请人：——

  公开号：US20040002493A1

  公开（公告）日：2004-01-01

  A pharmaceutical composition, which comprises a benzoic acid derivative of formula (I) 1 wherein R 1 is COOH, COOR 6 etc.; A, B is carbocyclic ring or heterocyclic ring; R 2 is alkyl, alkenyl, alkynyl etc.; R 4 is alkyl, cycloalkyl etc.; R 5 is carbocyclic ring or heterocyclic ring; or non-toxic salts thereof. The compound of the formula (I) can bind to Prostaglandin E 2 receptors, especially, EP 3 receptor and/or EP 4 receptor and show the antagonizing activity, and useful for the prevention and/or treatment of disease, for example, pain, allergy, Alzheimer's disease, cancer.

  一种药物组合物，包括化学式(I)1中的苯甲酸衍生物，其中R1为COOH，COOR6等；A、B为碳环或杂环；R2为烷基、烯基、炔基等；R4为烷基、环烷基等；R5为碳环或杂环；或其非毒性盐。化合物的化学式(I)可以与前列腺素E2受体结合，特别是EP3受体和/或EP4受体，并显示拮抗活性，对于预防和/或治疗疾病，例如疼痛、过敏、阿尔茨海默病、癌症等具有用处。
• OXIME ESTER
  申请人：Nishimae Yuichi

  公开号：US20130188270A1

  公开（公告）日：2013-07-25

  Compounds of the formula (I), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 for example independently of each other are hydro-gen, C 1 -C 20 alkyl, (II), COR 16 or NO 2 , provided that at least one pair of R 1 and R 2 , R 2 and R 3 , R 3 and R 4 , R 5 and R 6 , R 6 and R 7 , or R 7 and R 8 is (III); R 9 , R 10 , R 11 and R 12 for example independently of each other are hydrogen, C 1 -C 20 alkyl which optionally substituted; or R 9 , R 10 , R 11 , and R 12 independently of each other are unsubstituted or substituted phenyl; X is CO or a direct bond; R 13 is for example C 1 -C 20 alkyl which optionally is substituted, C 2 -C 12 alkenyl, C 4 -C 8 cycloalkenyl, C 2 -C 12 alkinyl, C 3 -C 10 -cycloalkyl, phenyl or naphthyl both of which are optionally substituted; R 14 is for example hydrogen, C 3 -C 8 cycloalkyl, C 2 -C 5 alkenyl, C 1 -C 20 alkoxy, C 1 -C 20 alkyl, phenyl or naphthyl; R 15 is for example C 6 -C 20 aryl or C 5 -C 20 heteroaryl; R 16 is for example C 6 -C 20 aryl which is unsubstituted or substituted by one or more C 1 -C 20 alkoxy or C 1 -C 20 alkyl; are in particular suitable as photoinitiators for color filter applications.

  式(I)的化合物，其中R1、R2、R3、R4、R5、R6、R7和R8，例如独立地是氢、C1-C20烷基、(II)、COR16或NO2，条件是至少有一对R1和R2、R2和R3、R3和R4、R5和R6、R6和R7或R7和R8是(III)；R9、R10、R11和R12，例如独立地是氢、C1-C20烷基，可选择地被取代；或者R9、R10、R11和R12独立地是未取代或取代的苯基；X是CO或直接键；R13，例如C1-C20烷基，可选择地被取代，C2-C12烯基，C4-C8环烯基，C2-C12炔基，C3-C10环烷基，苯基或者萘基，两者可选择地被取代；R14，例如氢，C3-C8环烷基，C2-C5烯基，C1-C20烷氧基，C1-C20烷基，苯基或者萘基；R15，例如C6-C20芳基或C5-C20杂芳基；R16，例如C6-C20芳基，未取代或被一个或多个C1-C20烷氧基或C1-C20烷基取代；特别适用于彩色滤光片应用的光引发剂。
• [EN] OXIME ESTER DERIVATIVES OF BENZOCARBAZOLE COMPOUNDS AND THEIR USE AS PHOTOINITIATORS IN PHOTOPOLYMERIZABLE COMPOSITIONS<br/>[FR] DÉRIVÉS ESTER D'OXIME DE BENZOCARBAZOLES ET LEUR UTILISATION COMME PHOTOINITIATEURS DANS DES COMPOSITIONS PHOTOPOLYMÉRISABLES
  申请人：BASF SE

  公开号：WO2012045736A1

  公开（公告）日：2012-04-12

  Compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7 and R8 for example independently of each other are hydro- gen, C1-C20alkyl, (II), COR16 or NO2, provided that at least one pair of R1 and R2, R2 and R3, R3 and R4, R5 and R6, R6 and R7, or R7 and R8 is (III); R9, R10, R11 and R12 for example independently of each other are hydrogen, C1-C20alkyl which optionally substituted; or R9, R10, R11, and R12 independently of each other are unsubstituted or substituted phenyl; X is CO or a direct bond; R13 is for example C1-C20alkyl which optionally is substituted, C2-C12alkenyl, C4- C8cycloalkenyl, C2-C12alkinyl, C3-C10cycloalkyl, phenyl or naphthyl both of which are optionally substituted; R14 is for example hydrogen, C3-C8cycloalkyl, C2-C5alkenyl, C1-C20alkoxy, C1-C20alkyl, phenyl or naphthyl; R15 is for example C6-C20aryl or C5-C20heteroaryl; R16 is for example C6-C20aryl which is unsubstituted or substituted by one or more C1-C20alkoxy or C1-C20alkyl; are in particular suitable as photoinitiators for color filter applications.

  式(I)的化合物，其中R1、R2、R3、R4、R5、R6、R7和R8例如彼此独立地为氢、C1-C20烷基、(II)、COR16或NO2，前提是至少有一对R1和R2、R2和R3、R3和R4、R5和R6、R6和R7或R7和R8为(III)；R9、R10、R11和R12例如彼此独立地为氢、C1-C20烷基，可以选择地取代；或者R9、R10、R11和R12彼此独立地为未取代或取代的苯基；X为CO或直接键；R13例如为C1-C20烷基，可以选择地取代，C2-C12烯基，C4-C8环烯基，C2-C12炔基，C3-C10环烷基，苯基或萘基，两者均可以选择地取代；R14例如为氢、C3-C8环烷基、C2-C5烯基、C1-C20烷氧基、C1-C20烷基、苯基或萘基；R15例如为C6-C20芳基或C5-C20杂芳基；R16例如为未取代或取代的C6-C20芳基，其取代基为一个或多个C1-C20烷氧基或C1-C20烷基；特别适用于彩色滤光片应用的光引发剂。