lithium chloroacetylide | 6180-21-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代乙炔及其衍生物
• 英文名称: lithium chloroacetylide
• 英文别名: chloroethynyl-lithium；chloro-acetylene; lithium chloro acetylenide；Chlor-acetylen; Lithium-chloracetylenid；Chloraethinyllithium；Lithium-chloracetylenid
• CAS: 6180-21-8
• 化学式: C₂ClLi
• 分子量: 66.416
• InChiKey: KWRQFEGKWYBRPA-UHFFFAOYSA-N

物化性质

• 沸点：
  101°C

计算性质

• 辛醇/水分配系数(LogP)：
  0.39
• 重原子数：
  4
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  lithium chloroacetylide 、 methylammonium carbonate 在 乙醚 作用下， 生成 3-氯丙-2-炔酸
  参考文献：
  名称：

  Viehe, Chemische Berichte, 1959, vol. 92, p. 1950,1955

  摘要：

  DOI：
• 作为产物：
  描述：

  反-1,2-二氯乙烯 、 alkaline earth salt of/the/ methylsulfuric acid 在 乙醚 、 氨 作用下， 生成 lithium chloroacetylide
  参考文献：
  名称：

  A model of the thermal processing of particles in solar nebula shocks: Application to the cooling rates of chondrules

  摘要：

  Abstract— We present a model for the thermal processing of particles in shock waves typical of the solar nebula. This shock model improves on existing models in that the dissociation and recombination of H2 and the evaporation of particles are accounted for in their effects on the mass, momentum and energy fluxes. Also, besides thermal exchange with the gas and gas‐drag heating, particles can be heated by absorbing the thermal radiation emitted by other particles. The flow of radiation is calculated using the equations of radiative transfer in a slab geometry. We compute the thermal histories of particles as they encounter and pass through the shock.We apply this shock model to the melting and cooling of chondrules in the solar nebula. We constrain the combinations of shock speed and gas density needed for chondrules to reach melting temperatures, and show that these are consistent with shock waves generated by gravitational instabilities in the protoplanetary disk. After their melting, cooling rates of chondrules in the range 10–1000 K h−1 are naturally reproduced by the shock model. Chondrules are kept warm by the reservoir of hot shocked gas, which cools only as fast as the dust grains and chondrules themselves can radiate away the gas's energy. We predict a positive correlation between the concentration of chondrules in a region and the cooling rates of chondrules in that region. This correlation is supported by the unusually high frequency of (rapidly cooled) barred chondrules among compound chondrules, which must have collided preferentially in regions of high chondrule density. We discuss these and other compelling consistencies between the meteoritic record and the shock wave model of chondrule formation.

  DOI：

  10.1111/j.1945-5100.2002.tb01104.x

文献信息

• Synthesis of 13-alkyl-gon-4-ones
  申请人：Smith; Herchel

  公开号：US03959322A1

  公开（公告）日：1976-05-25

  The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.

  描述了通过新的全合成方法制备13-甲基孕-4-烯和新型13-聚碳烷基孕-4-烯。通过形成在1,3,5(10),9(11)和14-位置不饱和的四环孕烷结构，选择性地在B和C环中还原，并将所产生的芳香A环化合物转化为孕-4-烯，制备具有孕激素、合成激素和雄激素活性的13-烷基孕-4-烯。
• Synthesis of gon-4-enes
  申请人：Smith; Herchel

  公开号：US04002746A1

  公开（公告）日：1977-01-11

  1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17.alpha.-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.

  一种具有孕激素活性的治疗组合物，其活性成分为17-脂肪族羧酸酯的17α-乙炔基-18-甲基-19-去甲睾酮，以及用于该化合物的药用载体。
• Substitution des halogéno-1 alcynes-1 par les dérivés organométalliques du cuivre. accès à une nouvelle classe de synthons: application à
  作者：A. Commerçon、J.F. Normant、J. Villieras

  DOI：10.1016/0040-4020(80)87021-9

  日期：1980.1

  1-Bromo- and 1-iodo-1-alkynes are alkylated by organocopper(I) compounds. Alkenylcopper(I) derivatives undergo substitution with retention of configuration leading to conjugated and functional enynes, from which conjugated dienes can be obtained.

  1-溴-和1-碘-1-炔烃被有机铜（I）化合物烷基化。烯基铜（I）衍生物进行取代并保留构型，从而导致共轭和官能烯炔，从中可获得共轭二烯。
• Modified Steroid Hormones—XLVI
  作者：C. Burgess、D. Burn、P. Feather、M. Howarth、V. Petrow

  DOI：10.1016/s0040-4020(01)99074-x

  日期：1966.1

  Novel 17α-bromoethynyl, 17α-chloroethynyl, 17-αiodoethynyl, 17-αtrifluoropropynyl, 17α-vinyl and 17α-triflourovinyl-17β-hydroxy (and/or 17β-alkoxy)-steroids have been prepared for biological examination.

  已经制备了新颖的17α-溴乙炔基，17α-氯乙炔基，17-α碘乙炔基，17-α三氟丙炔基，17α-乙烯基和17α-三氟乙炔基-17β-羟基（和/或17β-烷氧基）-类固醇用于生物学检查。
• Darstellung und schwingungsspektren der verbindungen (CH3)3SiCCCl, (CH3)3GeCCCl, (CH3)3SnCCCl und (CH3)3PbCCCl
  作者：Wolfgang Steingross、Werner Zeil

  DOI：10.1016/s0022-328x(00)93645-3

  日期：1966.8

  The following compounds: (CH3)3SiCCCl, (CH3)3GeCCCl, (CH3)3SnCCCl and (CH3)3PbCCCl, have been synthesised. The IR and Raman spectra of these compounds have been investigated and the IR and Raman frequencies are interpreted in terms of the normal vibrations.

  下列化合物：（CH 3）3 SiCCCl，（CH 3）3 GeCCCl，（CH 3）3 SnCCCl和（CH 3）3 PbCCCl，已经合成。已经研究了这些化合物的IR和拉曼光谱，并根据正常振动来解释IR和拉曼频率。