5-(5-(5-aminopyridin-3-yl)thiophen-2-yl)-2-methylisoindolin-1-one | 1567836-37-6
中文名称
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中文别名
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英文名称
5-(5-(5-aminopyridin-3-yl)thiophen-2-yl)-2-methylisoindolin-1-one
英文别名
5-(5-(5-Aminopyridin-3-yl)thiophen-2-yl)-2-methylisoindolin-1-one；5-[5-(5-aminopyridin-3-yl)thiophen-2-yl]-2-methyl-3H-isoindol-1-one
CAS
1567836-37-6
化学式
C18H15N3OS
mdl
——
分子量
321.403
InChiKey
GGMQWLJFNYCYTL-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
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物化性质
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计算性质
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ADMET
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安全信息
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SDS
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制备方法与用途
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上下游信息
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文献信息
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表征谱图
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同类化合物
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相关功能分类
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相关结构分类
物化性质
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熔点：244-248 °C(Solvent: Methanol ; Dichloromethane)
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沸点：615.8±55.0 °C(Predicted)
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密度：1.330±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
计算性质
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辛醇/水分配系数(LogP)：2.2
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重原子数：23
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可旋转键数：2
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环数：4.0
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sp3杂化的碳原子比例：0.11
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拓扑面积：87.5
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氢给体数：1
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氢受体数：4
上下游信息
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上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 2-methyl-5-(thiophen-2-yl)isoindolin-1-one 1567836-35-4 C13H11NOS 229.302 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 4-fluoro-N-((5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)carbamothioyl)benzamide 1567837-79-9 C26H19FN4O2S2 502.593 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulphonamide 1567837-62-0 C24H19N3O3S2 461.565 —— 2,4-difluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzamide 1567837-01-7 C25H17F2N3O2S 461.492 —— 4-iodo-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567837-93-7 C24H18IN3O3S2 587.462 —— 4-fluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-44-5 C24H18FN3O3S2 479.556 —— 4-bromo-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-58-1 C24H18BrN3O3S2 540.461 —— 4-chloro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-50-3 C24H18ClN3O3S2 496.01 —— 4-cyano-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-73-0 C25H18N4O3S2 486.575 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)thiophene-3-sulfonamide 1567836-80-9 C22H17N3O3S3 467.593 —— 3-bromo-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-57-0 C24H18BrN3O3S2 540.461 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)-4-(trifluoromethyl)benzenesulfonamide 1567836-67-2 C25H18F3N3O3S2 529.563 —— 3-fluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-43-4 C24H18FN3O3S2 479.556 —— 4-methoxy-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-61-6 C25H21N3O4S2 491.591 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)pyridine-3-sulfonamide 1567836-76-3 C23H18N4O3S2 462.553 —— 4-(N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)sulfamoyl)benzoic acid 1567837-92-6 C25H19N3O5S2 505.575 —— 3-chloro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-49-0 C24H18ClN3O3S2 496.01 —— methyl 4-(N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)sulfamoyl)benzoate 1567838-08-7 C26H21N3O5S2 519.602 —— 2-bromo-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-56-9 C24H18BrN3O3S2 540.461 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)-3-(trifluoromethyl)benzenesulfonamide 1567838-01-0 C25H18F3N3O3S2 529.563 —— 2-chloro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-48-9 C24H18ClN3O3S2 496.01 —— 2-fluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-42-3 C24H18FN3O3S2 479.556 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)-4-nitrobenzenesulfonamide 1567836-71-8 C24H18N4O5S2 506.563 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)thiophene-2-sulfonamide 1567836-78-5 C22H17N3O3S3 467.593 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)pyridine-2-sulfonamide 1567836-74-1 C23H18N4O3S2 462.553 —— N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)-4-(trifluoromethoxy)benzenesulfonamide 1567836-66-1 C25H18F3N3O4S2 545.563 —— 3,4-difluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-46-7 C24H17F2N3O3S2 497.546 —— 3-methoxy-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-60-5 C25H21N3O4S2 491.591 —— ethyl 4-(N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)sulfamoyl)benzoate 1567838-09-8 C27H23N3O5S2 533.629 —— 3,4-dichloro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-52-5 C24H17Cl2N3O3S2 530.455 —— 2,4-dibromo-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567837-94-8 C24H17Br2N3O3S2 619.357 —— 3-chloro-4-methyl-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-69-4 C25H20ClN3O3S2 510.037 —— 2,4-difluoro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)benzenesulfonamide 1567836-38-7 C24H17F2N3O3S2 497.546 —— 2,4-dichloro-N-(5-(5-(2-methyl-1-oxoisoindolin-5-yl)thiophen-2-yl)pyridin-3-yl)ben