(4-hydroxymethyl-cyclopent-2-enyl)-methanol | 5587-68-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4-hydroxymethyl-cyclopent-2-enyl)-methanol
• 英文别名: [4-(hydroxymethyl)cyclopent-2-en-1-yl]methanol
• CAS: 5587-68-8
• 化学式: C₇H₁₂O₂
• 分子量: 128.171
• InChiKey: SBAFXJOYJXMBAV-UHFFFAOYSA-N

物化性质

• 沸点：
  249.3±15.0 °C(Predicted)
• 密度：
  1.075±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (4-hydroxymethyl-cyclopent-2-enyl)-methanol 、 三苯基氯甲烷 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 以45.7%的产率得到(4-trityloxymethyl-cyclopent-2-enyl)-methanol
  参考文献：
  名称：

  WO2006/50161

  摘要：

  公开号：

文献信息

• Therapeutic furopyrimidines and thienopyrimidines
  申请人：Babu S. Yarlagadda

  公开号：US20060165655A1

  公开（公告）日：2006-07-27

  The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and III are useful as anti-viral agents and/or as anti-cancer agents.

  本发明提供了式I、II和III的化合物，以及包含这些化合物的药物组合物，以及用于制备这些化合物的合成方法和中间体。式I、II和III的化合物可用作抗病毒剂和/或抗癌剂。
• Therapeutic Furopyrimidines and Thienopyrimidines
  申请人：Babu Yarlagadda S.

  公开号：US20080300200A1

  公开（公告）日：2008-12-04

  The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and III are useful as anti-viral agents and/or as anti-cancer agents.

  本发明提供了公式I、II和III所描述的化合物，以及包含这些化合物的药物组合物，以及用于制备这些化合物的合成方法和中间体。公式I、II和III的化合物可用作抗病毒剂和/或抗癌剂。
• THERAPEUTIC FUROPYRIMIDINES AND THIENOPYRIMIDINES
  申请人：Babu Yarlagadda S.

  公开号：US20120213735A1

  公开（公告）日：2012-08-23

  The invention provides compounds of formula I, II, and III as described herein, as well as pharmaceutical compositions comprising the compounds, and synthetic methods and intermediates that are useful for preparing the compounds. The compounds of formula I, II, and III are useful as anti-viral agents and/or as anti-cancer agents.

  本发明提供了式I、II和III的化合物，以及包含该化合物的药物组合物，以及用于制备该化合物的合成方法和中间体。式I、II和III的化合物可用作抗病毒剂和/或抗癌剂。
• NOVEL BRANCHED POLYETHYLENE GLYCOL AND USE THEREOF
  申请人：University of Tsukuba

  公开号：US20140329290A1

  公开（公告）日：2014-11-06

  The present invention allows formation of covalent bonds in a bioactive compound having at least one amino group so as to efficiently provide the compound modified with PEG. The present invention thus provides a functionalized polyethylene glycol having a structure that allows reaction of two aldehyde groups with one amino group to form two covalent bonds.
• US7429571B2
  申请人：——

  公开号：US7429571B2

  公开（公告）日：2008-09-30