3-phenylcholest-5-ene | 148364-28-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3-phenylcholest-5-ene
• 英文别名: 3β-phenyl-cholestene-(5)；3β-Phenyl-cholesten-(5)；(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-3-phenyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene
• CAS: 148364-28-7
• 化学式: C₃₃H₅₀
• 分子量: 446.76
• InChiKey: VIFXZSYAKTVMRM-DMQOEKFGSA-N

物化性质

• 沸点：
  524.7±20.0 °C(Predicted)
• 密度：
  0.98±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.81
• 重原子数：
  33.0
• 可旋转键数：
  6.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  3-phenylcholest-5-ene 在 乙醚 、 溶剂黄146 、 铂 作用下， 生成 3β-cyclohexyl-5α-cholestane
  参考文献：
  名称：

  Brine Disposal from Inland Desalination Plants

  摘要：

  Desalination plants are being widely used in the inland areas of many countries to supply water for domestic purposes. When these areas are far from the shorelines of salt-water bodies, the opportunity to dispose of the reject brine (also known as concentrate, reject water, or wastewater) back into these water bodies no longer exists, In such instances, the use of evaporation ponds is very significant, both economically and environmentally. Other alternatives for brine disposal may also be very effective in some instances. Under certain conditions, brine from desalination plants can have useful applications. Potentials for such applications are addressed in this paper along with a critical review of current innovative concepts for the disposal of reject brine from inland desalination plants. This paper will also assess the present status of disposal mechanisms of brine from desalination plants and outline future research areas that could be pursued for effective, economical, and environmentally sound means for brine disposal from such plants.

  DOI：

  10.1080/02508060208686992
• 作为产物：
  描述：

  cholesterol 、 苯 在 Fuller's Earth 作用下， 生成 3-phenylcholest-5-ene
  参考文献：
  名称：

  Brine Disposal from Inland Desalination Plants

  摘要：

  Desalination plants are being widely used in the inland areas of many countries to supply water for domestic purposes. When these areas are far from the shorelines of salt-water bodies, the opportunity to dispose of the reject brine (also known as concentrate, reject water, or wastewater) back into these water bodies no longer exists, In such instances, the use of evaporation ponds is very significant, both economically and environmentally. Other alternatives for brine disposal may also be very effective in some instances. Under certain conditions, brine from desalination plants can have useful applications. Potentials for such applications are addressed in this paper along with a critical review of current innovative concepts for the disposal of reject brine from inland desalination plants. This paper will also assess the present status of disposal mechanisms of brine from desalination plants and outline future research areas that could be pursued for effective, economical, and environmentally sound means for brine disposal from such plants.

  DOI：

  10.1080/02508060208686992

文献信息

• Cross-Coupling of Nonactivated Primary and Secondary Alkyl Halides with Aryl Grignard Reagents Catalyzed by Chiral Iron Pincer Complexes
  作者：Xile Hu、Gerald Bauer、Chi Cheung

  DOI：10.1055/s-0034-1380136

  日期：——

  Abstract Iron(III) bisoxazolinylphenylamido (bopa) pincer complexes are efficient precatalysts for the cross-coupling of nonactivated primary and secondary alkyl halides with phenyl Grignard reagents. The reactions proceed at room temperature in moderate to excellent yields. A variety of functional groups can be tolerated. The enantioselectivity of the coupling of secondary alkyl halides is low. Iron(III)

  摘要 铁（III）双恶唑啉基苯基酰胺基（bopa）钳形配合物是有效的预催化剂，用于未活化的伯烷基卤化物和仲烷基卤化物与苯基格氏试剂的交叉偶联。反应在室温下以中等至优异的产率进行。可以容许多种官能团。仲烷基卤化物的偶联的对映选择性低。 铁（III）双恶唑啉基苯基酰胺基（bopa）钳形配合物是有效的预催化剂，用于未活化的伯烷基卤化物和仲烷基卤化物与苯基格氏试剂的交叉偶联。反应在室温下以中等至优异的产率进行。可以容许多种官能团。仲烷基卤化物的偶联的对映选择性低。
• Kawasaki; Yamamura, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1939, vol. 59, p. 144,148
  作者：Kawasaki、Yamamura

  DOI：——

  日期：——
• Kawasaki; Yamamura, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1939, vol. 59, p. 418,dtsch. Ref. S. 144, 151
  作者：Kawasaki、Yamamura

  DOI：——

  日期：——
• Montmorillonite Clay Catalysis. VIII. Synthesis of Arylcholestenes by Friedelcrafts Reaction Catalysed by Montmorillonite K-10.
  作者：Li-Jun Li、Bo Lu∗∗、Tong-Shuang Li、Ji-Tai Li

  DOI：10.1080/00397919808006843

  日期：1998.4

  A series of 3 beta-arylcholestenes were synthesised by Friedel-Crafts reaction of cholesterol with arenes catalysed by montmorillonite K-10.
• Synthesis of alkylbenzenes by Friedel-Crafts reactions catalysed by K10-montmorillonite
  作者：Odette Sieskind、Pierre Albrecht

  DOI：10.1016/s0040-4039(00)77527-7

  日期：1993.2

  Monoalkylation of benzene with primary, secondary and tertiary alcohols took place in high yields when K10-montmorillonite was used as acidic catalyst. Unexpected formation of 1-phenylalkylbenzenes occurred, beside other isomers with primary alcohols. Monoalkylation with cholestanol and cholesterol was regiospecific and located at C-3. Clay-catalysed alkylbenzene formation may also be of geochemical interest.