Seloken

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Seloken
• 英文别名: 2,3-dihydroxybutanedioic acid;1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
• 化学式: C34H56N2O12
• 分子量: 684.8
• InChiKey: YGULWPYYGQCFMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  48
• 可旋转键数：
  21
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  217
• 氢给体数：
  8
• 氢受体数：
  14

文献信息

• THERAPEUTIC AEROSOL FORMULATIONS
  申请人：RORER INTERNATIONAL (HOLDINGS) INC.

  公开号：EP0460064A1

  公开（公告）日：1991-12-11
• EP0460064A4
  申请人：——

  公开号：EP0460064A4

  公开（公告）日：1992-04-01
• HEALTH CARE
  申请人：Rozmanith, Anthony I.

  公开号：EP2361092A1

  公开（公告）日：2011-08-31
• Health Care
  申请人：Rozmanith Anthony I.

  公开号：US20110144055A1

  公开（公告）日：2011-06-16

  The use of a pharmaceutical regimen to deter in an individual, as the individual ages, the development of a cardiovascular disease (CVD) or Alzheimer's disease or to treat an individual who has CVD or Alzheimer's, the individual ingesting on a daily basis a regimen comprising pharmaceutically effective amounts of magnesium salicylate and naproxen, the amount of the magnesium salicylate being no greater than about 260 mg, and also the use of a pharmaceutical regimen to treat an individual who has Type 2 diabetes, the regimen being ingested daily by the individual and comprising pharmaceutically effective amounts of at least one glucose-lowering drug and magnesium salicylate in an amount no greater than about 260 mg.
• [EN] THERAPEUTIC AEROSOL FORMULATIONS
  申请人：——

  公开号：WO1990009781A1

  公开（公告）日：1990-09-07

  [EN] Disclosed are self-propelled therapeutic aerosol compositions, and a process for the preparation thereof, comprising a micronized, water soluble, propellant insoluble homogeneous complex of a drug and an extender suspended in a propellant mixture.
  [FR] L'invention concerne des compositions aérosol thérapeutiques auto-propulsées, et un procédé pour leur préparation. Elles consistent en un complexe homogène insoluble dans l'agent propulseur, soluble dans l'eau, de particules de l'ordre du micron d'un médicament et d'un diluant en suspension dans un mélange propulseur.