α-allyl-β-(n-butyl)butyraldehyde | 58105-41-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: α-allyl-β-(n-butyl)butyraldehyde
• 英文别名: 3-Methyl-2-(prop-2-EN-1-YL)heptanal；3-methyl-2-prop-2-enylheptanal
• CAS: 58105-41-2
• 化学式: C₁₁H₂₀O
• 分子量: 168.279
• InChiKey: XMRDXLJWGHLFCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  在 盐酸 作用下， 反应 2.0h， 生成 α-allyl-β-(n-butyl)butyraldehyde
  参考文献：
  名称：

  Synthesis of ?,?-disubstituted aldehydes involving metallated 1-aza-1,3-butadienes in the presence of phosphine complexes of palladium

  摘要：

  A novel catalytic method was developed for the synthesis of alpha,beta-disubstituted aldehydes by the reaction of N-, O-, and S-containing allyl electrophiles with magnesium azaenolates obtained by metallation of alpha,beta-unsaturated imines by Grignard reagents. The reaction is carried out with high regio- and stereo-selectivity in the presence of phosphine complexes of palladium.

  DOI：

  10.1007/bf00963504

文献信息

• Synthesis of ?,?-disubstituted aldehydes involving metallated 1-aza-1,3-butadienes in the presence of phosphine complexes of palladium
  作者：U. M. Dzhemilev、A. G. Ibragimov、D. L. Minsker、R. R. Muslukhov、G. A. Tolstikov

  DOI：10.1007/bf00963504

  日期：1991.10

  A novel catalytic method was developed for the synthesis of alpha,beta-disubstituted aldehydes by the reaction of N-, O-, and S-containing allyl electrophiles with magnesium azaenolates obtained by metallation of alpha,beta-unsaturated imines by Grignard reagents. The reaction is carried out with high regio- and stereo-selectivity in the presence of phosphine complexes of palladium.