2-(3-(Tert-butyl)-4-hydroxy-5-(5-methoxy-2H-benzo[D][1,2,3]triazol-2-YL)phenoxy)ethyl methacrylate | 114166-73-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑类
• 英文名称: 2-(3-(Tert-butyl)-4-hydroxy-5-(5-methoxy-2H-benzo[D][1,2,3]triazol-2-YL)phenoxy)ethyl methacrylate
• 英文别名: 2-[3-tert-butyl-4-hydroxy-5-(5-methoxybenzotriazol-2-yl)phenoxy]ethyl 2-methylprop-2-enoate
• CAS: 114166-73-3
• 化学式: C₂₃H₂₇N₃O₅
• 分子量: 425.5
• InChiKey: KRSIODKTBYBKQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  31
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  95.7
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• [EN] COMPOUNDS FOR OPTICALLY ACTIVE DEVICES<br/>[FR] COMPOSÉS POUR DISPOSITIFS OPTIQUEMENT ACTIFS
  申请人：MERCK PATENT GMBH

  公开号：WO2020212543A1

  公开（公告）日：2020-10-22

  The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive unit, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalmic devices.

  本发明涉及包含光活性单元的聚合化合物的创新眼科设备，所述聚合化合物，以及特别适合用于组合物和眼科设备的特殊单体化合物。
• [EN] AZACOUMARIN AND AZATHIOCOUMARIN DERIVATIVES FOR USE IN OPTICALLY ACTIVE DEVICES<br/>[FR] DÉRIVÉS D'AZACOUMARINES ET D'AZATHIOCOUMARINE DESTINÉS À ÊTRE UTILISÉS DANS DES DISPOSITIFS OPTIQUEMENT ACTIFS
  申请人：MERCK PATENT GMBH

  公开号：WO2021233800A1

  公开（公告）日：2021-11-25

  The present invention relates to novel ophthalmic devices comprising polymerized compounds comprising a photoactive chromophore, said polymerized compounds, and special monomer compounds being particularly suitable for compositions and ophthalmic devices. The present invention is also directed to a process of changing the optical properties of said ophthalmic device or a precursor article for manufacturing said ophthalmic device.

  本发明涉及包括聚合物化合物的新型眼科器件，所述聚合物化合物包括光活性色素，以及特殊单体化合物，特别适用于眼科器件的组合物和眼科器件。本发明还涉及一种改变所述眼科器件的光学性能或用于制造所述眼科器件的前体物品的方法。
• Photochromic blue light filtering materials and ophthalmic devices
  申请人：Jani M. Dharmendra

  公开号：US20050254003A1

  公开（公告）日：2005-11-17

  Polymeric compositions have photochromic and blue-light filtering ability and are useful in the manufacture of ophthalmic medical devices. The polymeric compositions comprise a photochromic material incorporated into polymeric host materials and are activatable by blue light having a first wavelength range to become photochromic, and are thereby capable of absorbing blue light in a second wavelength range. Methods of making the compositions comprise incorporating a photochromic material into a polymeric host material.

  聚合物组合物具有光致变色和蓝光过滤能力，并可用于制造眼科医疗器械。该聚合物组合物包括将光致变色材料并入聚合物基材料中，可以通过第一波长范围的蓝光激活变成光致变色，并且因此能够吸收第二波长范围的蓝光。制造该组合物的方法包括将光致变色材料并入聚合物基材料中。
• SOFT ACRYLIC MATERIALS WITH HIGH REFRACTIVE INDEX AND MINIMIZED GLISTENING
  申请人：NOVARTIS AG

  公开号：US20150151022A1

  公开（公告）日：2015-06-04

  High refractive index acrylic device materials with reduced glistenings are disclosed. The device materials are particularly suitable for use as ophthalmic or otorhhinolaryngological device materials and comprises a poly(phenyl ether)-containing monomer and/or a poly(phenyl ether)-containing cross-linking agent.

  公开了具有减少闪光的高折射率丙烯酸酯器件材料。该器件材料特别适用于作为眼科或耳鼻喉科器件材料，并包括含有聚苯醚单体和/或聚苯醚交联剂的材料。
• WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX
  申请人：Novartis AG

  公开号：US20160235886A1

  公开（公告）日：2016-08-18

  Intraocular lens materials are disclosed. They are soft and very deformable and have a high refractive index, and a high glistening resistance in fully hydrated state. They are particularly suitable for making wet-packed intraocular lenses (IOLs) which can be delivered through sub 2.0 mm incisions.

  本文披露了一种人工晶体材料。该材料柔软、易变形，具有高折射率和高抗水晶体闪光的特点。它特别适用于制作湿式包装的人工晶体（IOL），可通过小于2.0毫米的切口进行输送。