4-isopropylidene-2-methoxyadamantane | 134150-32-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-isopropylidene-2-methoxyadamantane
• 英文别名: 2-methoxy-4-propan-2-ylideneadamantane
• CAS: 134150-32-6
• 化学式: C₁₄H₂₂O
• 分子量: 206.328
• InChiKey: FOPOXPBTZCNXTR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15.0
• 可旋转键数：
  1.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  9.23
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  2,4-dimethylmethano-2,4-didehydroadamantane 在 甲醇 作用下， 生成 2-Methoxy-2,4-(dimethylmethano)adamantane 、 2-Isopropenyl-2,4-didehydroadamantane 、 4-isopropylidene-2-methoxyadamantane
  参考文献：
  名称：

  2,4-dimethylmethano-2,4-didehydroadamantane and its reactivity in relation to the unsubstituted analogue

  摘要：

  2,4-Dimethylmethano-2,4-didehydroadamantane (1) has been prepared and the gem-dimethyl substituent effects of propellane 1 in relation to its unsubstituted analogue 2 were studied. The reactivity of 1 is considerably greater than that of 2 due to the higher nucleophilicity of its central bond. However, 1 is thermally more stable than 2.

  DOI：

  10.1016/s0040-4039(00)74297-3