(3-methyl)tetrahydrophthalic anhydride | 35438-81-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异苯并呋喃
• 英文名称: (3-methyl)tetrahydrophthalic anhydride
• 英文别名: (+/-)-3c-methyl-cyclohex-4-ene-1r,2c-dicarboxylic acid-anhydride；(+/-)-3c-Methyl-cyclohex-4-en-1r,2c-dicarbonsaeure-anhydrid；3-Methyl-cyclohexen-(4)-dicarbonsaeure-(1.2)-anhydrid；(3aS,4S,7aR)-4-Methyl-3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione
• CAS: 35438-81-4
• 化学式: C₉H₁₀O₃
• 分子量: 166.177
• InChiKey: XPEKVUUBSDFMDR-XVMARJQXSA-N

物化性质

• 熔点：
  40-41 °C
• 沸点：
  122-134 °C(Press: 4 Torr)
• 密度：
  1.204±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (3-methyl)tetrahydrophthalic anhydride 在 palladium on activated charcoal N,N-二丁基苯胺 、 氢气 作用下， 以 乙酸乙酯 为溶剂， 生成 (+/-)-3t-methyl-cyclohexane-1r,2c-dicarboxylic acid-anhydride
  参考文献：
  名称：

  炔砜作为烯烃偶极当量在合成（±）-铝毒素C中的用途

  摘要：

  顺式-2-氨基-反式-6-甲基环己烷甲酸甲酯（3）与1-对-（甲苯磺酰基）-1-戊炔（4）的环加成反应得到相应的烯胺酮2，然后将其还原为（±）-pumiliotoxin C（1）。因此，炔砜4在该方法中用作烯烃偶极子5的合成当量。

  DOI：

  10.1016/s0040-4039(96)02506-3
• 作为产物：
  描述：

  间戊二烯 在 马来酸酐 、 氢气 、 苦味酸 、 苯 作用下， 生成 (3-methyl)tetrahydrophthalic anhydride
  参考文献：
  名称：

  cis- and trans-Piperlyenes^1,2

  摘要：

  DOI：

  10.1021/ja01202a020

文献信息

• A stereoselective total synthesis of nat (−) prostaglandin E1 and its optical antipode
  作者：H.L. Slates、Z.S. Zelawski、D. Taub、N.L. Wendler

  DOI：10.1016/s0040-4020(01)97142-x

  日期：1974.1

  A stereoselective total synthesis of nat (−) prostaglandin E1 and its optical antipode employing the Diels-Alder adduct oftrans-piperylene and maleic anhydride as starting material is described.

  描述了以反式-亚戊二烯和马来酸酐的狄尔斯-阿尔德加合物为起始原料的nat（-）前列腺素E 1的立体选择性全合成及其旋光对映体。
• Efficient Asymmetric Synthesis of Unnatural β-Amino Acids
  作者：Carsten Bolm、Ingo Schiffers、Christian L. Dinter、Laurent Defrère、Arne Gerlach、Gerhard Raabe

  DOI：10.1055/s-2001-16745

  日期：——

  The simple and highly enantioselective methanolysis of cyclic meso-anhydrides mediated by cinchona alkaloids leads to a broad variety of dicarboxylic acid mono-methyl esters with up to 99% ee. From these products, unnatural N-protected β-amino esters can be obtained by means of Curtius degradation of the corresponding acyl azides. Subsequent cleavage of the protecting groups leads to the free β-amino acids in excellent yields. By enantiomer differentiating opening of racemic anhydrides, synthetically highly useful regioisomeric amino acid esters become readily available.

  由金鸡纳生物碱介导的环状内消旋酸酐的简单且高度对映选择性的甲醇分解可产生多种二羧酸单甲酯，其 ee 高达 99%。从这些产品中，可以通过 Curtius 降解相应的酰基叠氮获得非天然的 N-保护的 β-氨基酯。随后保护基团的裂解导致游离β-氨基酸的产率极好。通过外消旋酸酐的对映异构体差异化打开，合成上非常有用的区域异构氨基酸酯变得容易获得。
• POLYESTER AND POLYMER MODIFIER COMPRISING THE POLYESTER AS ACTIVE INGREDIENT
  申请人：Zeon Corporation

  公开号：EP1270637A1

  公开（公告）日：2003-01-02

  A polyester having a weight average molecular weight of 10,000 to 200,000, a hydroxyl value of 30 to 200 mgKOH/g, an acid value of not larger than 5 mgKOH/g and a glass transition temperature of 35 to 60°C, which is obtained by polycondensing a polycarboxylic acid ingredient comprising as a principal ingredient a polycarboxylic acid compound selected from alicyclic polycarboxylic acids and anhydrides thereof, which have a carboxyl group at each of two adjacent carbon atoms, with a polyhydric alcohol ingredient comprising as principal ingredients an alkylene glycol having 2 or 3 carbon atoms and a tetrahydric or higher-hydric alcohol. By incorporating a modifier for polymer, comprising this polyester as an effective ingredient, in a polymer a polymer composition is obtained which gives a shaped article exhibiting improved adhesion to a thermosetting resin.

  一种聚酯，其重量平均分子量为 10,000 至 200,000，羟值为 30 至 200 mgKOH/g，酸值不大于 5 mgKOH/g，玻璃化温度为 35 至 60°C，由聚羧酸成分与聚水醇成分缩聚而成，聚羧酸成分的主要成分是选自脂环族聚羧酸及其酸酐的聚羧酸化合物、多羧酸成分的主要成分是具有 2 个或 3 个碳原子的亚烷基二醇和四水醇或高水醇。在聚合物中加入以这种聚酯为有效成分的聚合物改性剂，就能得到一种聚合物组合物，这种组合物能使成型物品与热固性树脂的粘附性得到改善。
• AIR-DRYING POLYESTER (METH)ACRYLATE RESIN COMPOSITION, STRUCTURE AND METHOD FOR PROVIDING SAME
  申请人：DIC Corporation

  公开号：EP2395033A1

  公开（公告）日：2011-12-14

  An object of the present invention is to provide an air-drying polyester (meth)acrylate resin composition in a curing system of a ketone peroxide curing agent and a cobalt-based curing accelerator, the resin composition being used as a topcoat in the field of civil engineering and construction, and having such good properties as, when coated or stacked, being capable of forming a cured coating film with no bubbles remaining therein due to non-bubbling properties of suppressing the generation of bubbles in the course of the curing reaction and being free from problems related to room-temperature curability such as a retarded gelation time, even after being stored for about one month; a structure coated with the resin composition; and a method for applying the resin composition.

  本发明的目的是在过氧化酮固化剂和钴基固化促进剂的固化体系中提供一种气干型聚酯（甲基）丙烯酸酯树脂组合物，该树脂组合物可用作土木工程和建筑领域的面漆，并且在涂覆或堆叠时具有以下良好性能、由于具有抑制固化反应过程中产生气泡的无气泡特性，因此能够形成无气泡残留的固化涂膜，即使在存放约一个月后，也不会出现凝胶时间延缓等与室温固化性有关的问题；涂有该树脂组合物的结构；以及应用该树脂组合物的方法。
• Polyester and polymer modifier comprising the polyester as active ingredient
  申请人：——

  公开号：US20020193556A1

  公开（公告）日：2002-12-19

  A polyester having a weight average molecular weight of 10,000 to 200,000, a hydroxyl value of 30 to 200 mgKOH/g, an acid value of not larger than 5 mgKOH/g and a glass transition temperature of 35 to 60° C., which is obtained by polycondencing a polycarboxylic acid ingredient comprising as a principal ingredient a polycarboxylic acid compound selected from alicyclic polycarboxylic acids and anhydrides thereof, which have a carboxyl group at each of adjacent two carbon atoms, with a polyhydric alcohol ingredient comprising as principal ingredients an alkylene glycol having 2 or 3 carbon atoms and a tetrahydric or higher-hydric alcohol. By incorporating a modifier for polymer, comprising this polyester as an effective ingredient, in a polymer, a polymer composition is obtained which gives a shaped article exhibiting improved adhesion to a thermosetting resin.

  一种聚酯，其重量平均分子量为10,000至200,000，羟值为30至200 mgKOH/g，酸值不大于5 mgKOH/g，玻璃化温度为35至60°C、聚羧酸成分，其主要成分是选自脂环族聚羧酸及其酸酐的聚羧酸化合物，这些化合物在相邻的两个碳原子上各具有一个羧基，其主要成分是具有 2 或 3 个碳原子的亚烷基二醇和四水或四水以上的醇。通过在聚合物中加入以这种聚酯为有效成分的聚合物改性剂，可以得到一种聚合物组合物，这种组合物可以使成型物品与热固性树脂的粘附性得到改善。