1,4-bis(4-methyl-3-oxopentanoyl)-benzene | 123448-21-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,4-bis(4-methyl-3-oxopentanoyl)-benzene
• 英文别名: 1,1'-(1,4-Phenylene)bis(4-methyl-1,3-pentanedione)；4-methyl-1-[4-(4-methyl-3-oxopentanoyl)phenyl]pentane-1,3-dione
• CAS: 123448-21-5
• 化学式: C₁₈H₂₂O₄
• 分子量: 302.37
• InChiKey: CIYQRJUFTUGUPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  22
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  68.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Ultraviolet radiation absorbing compositions of bis-1,3-diketone derivatives of benzene
  申请人：ICI AMERICAS INC.

  公开号：EP0376511A2

  公开（公告）日：1990-07-04

  Sunscreen compositions are described which contain certain bis-1,3-diketone derivatives of benzene when incorporated in a carrier in amounts ranging from 0.l-50% by weight.

  所述的防晒组合物含有某些苯的双-1,3-二酮衍生物，其在载体中的含量为 0.l-50% （按重量计）。
• Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same
  申请人：KAO CORPORATION

  公开号：EP0416564A2

  公开（公告）日：1991-03-13

  A novel aroyl ketone derivative represented by formula (I) is disclosed. Ar(COCH₂COR¹)n      (I) wherein R¹ represents a saturated or unsaturated hydrocarbon group having 1-24 carbon atoms, or a linear or branched alkoxyalkyl or alkenyloxyalkyl group having 1-24 carbon atoms, dialkylamino group having 1-24 carbon atoms, Ar represents a benzene or naphthalene ring which may be substituted with one or more hydroxyl groups, alkoxy groups having 1-24 carbon atoms, alkenyloxy groups having 1-24 carbon atoms, polyoxyleneoxy groups, or α-­methylenedioxy groups, and n denotes an integer of 1-4. An UV-ray absorber and cosmetic composition comprising the aroyl ketone derivative of formula (I) are also disclosed. Aroyl ketone derivative (I) of the present invention can provide an excellent UV-ray absorbing effect and has outstanding stability against light, and the UV-ray absorber or cosmetic composition containing the aroyl ketone derivative (I) can exhibit an excellent sunscreening effect.

  本发明公开了一种由式(I)代表的新型芳基酮衍生物。 Ar(COCH₂COR¹)n (I) 其中 R¹ 代表具有 1-24 个碳原子的饱和或不饱和烃基，或具有 1-24 个碳原子的直链或支链烷氧基或烯氧基烷基，具有 1-24 个碳原子的二烷基氨基，Ar 代表可被一个或多个羟基、具有 1-24 个碳原子的烷氧基、具有 1-24 个碳原子的烯氧基、聚氧乙烯氧基或 α-亚甲二氧基取代的苯环或萘环，n 表示 1-4 的整数。此外，还公开了一种紫外线吸收剂和包含式（I）丙酮衍生物的化妆品组合物。本发明的芳基酮衍生物（I）可提供优异的紫外线吸收效果，并具有出色的耐光稳定性，含有该芳基酮衍生物（I）的紫外线吸收剂或化妆品组合物可表现出优异的防晒效果。
• US4822870A
  申请人：——

  公开号：US4822870A

  公开（公告）日：1989-04-18
• US4999419A
  申请人：——

  公开号：US4999419A

  公开（公告）日：1991-03-12
• US5146002A
  申请人：——

  公开号：US5146002A

  公开（公告）日：1992-09-08