4-methoxy-2',3-dimethylbenzophenone | 41295-37-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methoxy-2',3-dimethylbenzophenone
• 英文别名: 2',3-Dimethyl-4-methoxybenzophenon；4-Methoxy-2',3-dimethylbenzophenon；(4-methoxy-3-methylphenyl)-(2-methylphenyl)methanone
• CAS: 41295-37-8
• 化学式: C₁₆H₁₆O₂
• mdl: MFCD12069255
• 分子量: 240.302
• InChiKey: OJUHYBHGOJCPDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.187
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-methoxy-2',3-dimethylbenzophenone 在 氢溴酸 、 溶剂黄146 作用下， 生成 (4-hydroxy-3-methylphenyl)(2-methylphenyl)methanone
  参考文献：
  名称：

  Glycosylated derivatives of benzophenone, benzhydrol and benzhydril as potential venous antithrombotic agents

  摘要：

  A series of glycosylated derivatives of benzophenone, benzhydrol, and benzhydril has been synthesized and evaluated for potential activity as venous antithrombotic agents. Studies on structure-activity relationships revealed that compounds having an electron-withdrawing group in the benzhydril or benzhydrol moiety, and specifically those having the beta-D-xylopyranosyl structure in the sugar moiety, were good antithrombotic agents in a rat model of venous thrombosis.

  DOI：

  10.1021/jm00059a015
• 作为产物：
  描述：

  2-甲基苯甲醚 、 邻甲基苯甲酰氯 在 苯 、 magnesium sulfate 作用下， 以 polyphosphoric acid 、 水 为溶剂， 反应 72.0h， 以to give 7.5 g of product (31%), m.p. 72°-73°C.的产率得到4-methoxy-2',3-dimethylbenzophenone
  参考文献：
  名称：

  Benzophenone herbicides

  摘要：

  上述公式的化合物为：##SPC1## 其中R为烷基或烯丙基，R'为烷基，R"为烷基、烷氧基或三卤代烷基，n为1或2。含有这些化合物的组合物表现出除草活性。

  公开号：

  US03954875A1

文献信息

• US3953498A
  申请人：——

  公开号：US3953498A

  公开（公告）日：1976-04-27
• US3954875A
  申请人：——

  公开号：US3954875A

  公开（公告）日：1976-05-04
• US3983176A
  申请人：——

  公开号：US3983176A

  公开（公告）日：1976-09-28
• Glycosylated derivatives of benzophenone, benzhydrol and benzhydril as potential venous antithrombotic agents
  作者：Francois Bellamy、Derek Horton、Jean Millet、Francois Picart、Soth Samreth、Jean Bernard Chazan

  DOI：10.1021/jm00059a015

  日期：1993.4

  A series of glycosylated derivatives of benzophenone, benzhydrol, and benzhydril has been synthesized and evaluated for potential activity as venous antithrombotic agents. Studies on structure-activity relationships revealed that compounds having an electron-withdrawing group in the benzhydril or benzhydrol moiety, and specifically those having the beta-D-xylopyranosyl structure in the sugar moiety, were good antithrombotic agents in a rat model of venous thrombosis.
• Benzophenone herbicides
  申请人：Rohm and Haas Company

  公开号：US03954875A1

  公开（公告）日：1976-05-04

  Compounds of the formula ##SPC1## Wherein R is an alkyl or an allyl group, R' is an alkyl group, R" is an alkyl group, an alkoxy group, or a trihaloalkyl group, and n is 1 or 2 And compositions containing these compounds exhibit herbicidal activity.

  式为##SPC1##的化合物，其中R是烷基或烯丙基，R'是烷基，R"是烷基、烷氧基或三卤代烷基，n为1或2。含有这些化合物的组合物具有除草活性。