Benzenaminium, N-methylidyne- | 102397-36-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Benzenaminium, N-methylidyne-
• 英文别名: N-phenylmethanimine
• CAS: 102397-36-4
• 化学式: C₇H₆N
• 分子量: 104.131
• InChiKey: SQJVPMNTLGHXJL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  4.4
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  Benzenaminium, N-methylidyne- 、 3-(3,4-dihydro-2H-pyrrol-5-yl)propan-1-ol 在 三乙胺盐酸盐 作用下， 以 甲苯 为溶剂， 以46%的产率得到N-phenyltetrahydro-1H-pyrrolizine-7a(5H)-carboxamide
  参考文献：
  名称：

  使用亚胺和异腈直接制备吡咯烷核苷

  摘要：

  摘要 描述了用于形成7a-取代的非天然吡咯嗪核苷的酸介导的环化反应。为了达到这个目标，吡咯啉3-（3,4-二氢-2- ħ吡咯-5-基）丙-1-醇与大量的各种异腈直接导致目标化合物的反应。该反应操作简单，并且可以耐受空气和水，并且所得的吡咯烷核苷可以进一步转化为相应的氧化和还原的衍生物。 描述了用于形成7a-取代的非天然吡咯嗪核苷的酸介导的环化反应。为了达到这个目标，吡咯啉3-（3,4-二氢-2- ħ吡咯-5-基）丙-1-醇与大量的各种异腈直接导致目标化合物的反应。该反应操作简单，并且可以耐受空气和水，并且所得的吡咯烷核苷可以进一步转化为相应的氧化和还原的衍生物。

  DOI：

  10.1055/s-0034-1380433
• 作为产物：
  描述：

  三苯基乙烯亚胺 在 氧气 、 copper dichloride 作用下， 以 N,N-二甲基甲酰胺 、 苯 为溶剂， 生成 二苯甲酮 、 Benzenaminium, N-methylidyne- 、 异氰酸苯酯
  参考文献：
  名称：

  Barker, Marvin M.; Perumal, Subramoniam I., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1982, vol. 21, # 6, p. 549 - 552

  摘要：

  DOI：

文献信息

• Fused heterocyclic compound
  申请人：Yasuma Tsuneo

  公开号：US20090247746A1

  公开（公告）日：2009-10-01

  The present invention provides a glucokinase activator containing a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof or a prodrug thereof. According to the present invention, a glucokinase activator useful as a pharmaceutical agent such as agent for the prophylaxis or treatment of diabetes, obesity and the like, and the like can be provided.

  本发明提供了一种含有式(I)所表示的化合物的葡萄糖激酶激活剂，其中每个符号如规范中所定义，或其盐或前药。根据本发明，可以提供一种葡萄糖激酶激活剂，其作为药物剂量，如预防或治疗糖尿病、肥胖症等剂量，等等。
• INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS
  申请人：LG LIFE SCIENCES LTD.

  公开号：US20140024618A1

  公开（公告）日：2014-01-23

  The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.

  本发明涉及新的吲哚化合物、药学上可接受的盐或其异构体，用于预防或治疗细胞坏死和坏死相关疾病。本发明还涉及一种用于预防或治疗细胞坏死和坏死相关疾病的方法和组合物，该组合物包含所述吲哚化合物作为活性成分。
• Active ray curable ink-jet ink, image forming method and ink-jet recording apparatus
  申请人：Takabayashi Toshiyuki

  公开号：US20080105162A1

  公开（公告）日：2008-05-08

  An active ray curable ink-jet ink comprising at least one type of a photo acid generating compound, a cationic polymerizable compound and a pigment, wherein the active ray curable ink-jet ink contains a fatty acid amine salt comprising a fatty acid having a carbon number of 6-18 and a primary, a secondary or a tertiary amine having a carbon number of 4-12 in an amount of 0.01-0.70 weight % based on the total weight of the ink-jet ink.
• CATALYSTS AND METHODS FOR POLYMER SYNTHESIS
  申请人：Novomer, Inc.

  公开号：US20130144033A1

  公开（公告）日：2013-06-06

  The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.
• SALEN COMPLEXES WITH DIANIONIC COUNTERIONS
  申请人：Novomer, Inc.

  公开号：US20170107241A1

  公开（公告）日：2017-04-20

  The present invention describes metal salen complexes having dianionic counterions. Such complexes can be readily precipitated and provide an economical method for the purification and isolation of the complexes, and are useful to prepare novel polymer compositions.