1-(3-Acetyloxiran-2-yl)ethanone | 89022-64-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-(3-Acetyloxiran-2-yl)ethanone
• CAS: 89022-64-0
• 化学式: C₆H₈O₃
• 分子量: 128.13
• InChiKey: PUKJXVHOAGCUMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  46.7
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Methods For Obtaining Optically Active Epoxides And Vicinal Diols From Meso-Epoxides
  申请人：Botes Leonora Adriana

  公开号：US20070275448A1

  公开（公告）日：2007-11-29

  The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active vicinal diols from meso-epoxides.

  本发明提供了酵母菌株和由这些酵母菌株的基因编码的多肽，具有对映特异性的中间体环氧水解酶活性。本发明还涵盖编码这种多肽的核酸分子，含有这种核酸分子的载体以及含有这种载体的细胞。本发明还涵盖了从中间体环氧化物中获得光学活性邻二醇的方法。
• COMPOUNDS THAT MODULATE EGFR ACTIVITY AND METHODS FOR TREATING OR PREVENTING CONDITIONS THEREWITH
  申请人：GRAY Nathanael S.

  公开号：US20110207736A1

  公开（公告）日：2011-08-25

  Provided are compounds and methods for treating or preventing kinase-mediated disorders therewith.

  提供了化合物和方法，用于治疗或预防由激酶介导的疾病。
• Compounds that modulate EGFR activity and methods for treating or preventing conditions therewith
  申请人：Gray Nathanael S.

  公开号：US20130137709A1

  公开（公告）日：2013-05-30

  Provided are compounds and methods for treating or preventing kinase-mediated disorders therewith.

  提供了化合物和方法，用于治疗或预防激酶介导的疾病。
• Compounds that Modulate EGFR Activity and Methods for Treating or Preventing Conditions Therewith
  申请人：Gatekeeper Pharmaceuticals, Inc.

  公开号：US20140011810A1

  公开（公告）日：2014-01-09

  Provided are compounds and methods for treating or preventing kinase-mediated disorders therewith.

  提供了用于治疗或预防激酶介导的疾病的化合物和方法。
• US9879028B2
  申请人：——

  公开号：US9879028B2

  公开（公告）日：2018-01-30