2-[(E)-2-(4-methoxyphenyl)ethenyl]benzo[c]phenanthrene | 41866-94-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 菲及其衍生物
• 英文名称: 2-[(E)-2-(4-methoxyphenyl)ethenyl]benzo[c]phenanthrene
• CAS: 41866-94-8
• 化学式: C₂₇H₂₀O
• 分子量: 360.455
• InChiKey: XMNBQGPETBIAPV-VOTSOKGWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-[(E)-2-(4-methoxyphenyl)ethenyl]benzo[c]phenanthrene 在 碘 、 三溴化硼 作用下， 以 二氯甲烷 、 甲苯 为溶剂， 反应 2.0h， 生成 2-hydroxy-hexahelicene
  参考文献：
  名称：

  Synthesis and resolution of 2-hydroxyhexahelicene

  摘要：

  2-Hydroxyhexahelicene has been prepared in good yield and purity via a three-step sequence involving palladium-catalysed Heck coupling and classical oxidative photocyclisation reactions. The two enantiomers of this hexacyclic helicenol have been separated using (S)-(-)-camphanoyl chloride as the chiral resolving agent. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.11.036
• 作为产物：
  描述：

  4-甲氧基苯乙烯 、 2-溴苯并(c)菲 在 trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II) 、 sodium acetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 48.0h， 以76%的产率得到2-[(E)-2-(4-methoxyphenyl)ethenyl]benzo[c]phenanthrene
  参考文献：
  名称：

  Synthesis and resolution of 2-hydroxyhexahelicene

  摘要：

  2-Hydroxyhexahelicene has been prepared in good yield and purity via a three-step sequence involving palladium-catalysed Heck coupling and classical oxidative photocyclisation reactions. The two enantiomers of this hexacyclic helicenol have been separated using (S)-(-)-camphanoyl chloride as the chiral resolving agent. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.11.036

文献信息

• Synthesis and resolution of 2-hydroxyhexahelicene
  作者：Mourad Ben Braiek、Faouzi Aloui、Béchir Ben Hassine

  DOI：10.1016/j.tetlet.2012.11.036

  日期：2013.1

  2-Hydroxyhexahelicene has been prepared in good yield and purity via a three-step sequence involving palladium-catalysed Heck coupling and classical oxidative photocyclisation reactions. The two enantiomers of this hexacyclic helicenol have been separated using (S)-(-)-camphanoyl chloride as the chiral resolving agent. (C) 2012 Elsevier Ltd. All rights reserved.