8-ethyl-1-oxaspiro[4.5]-decan-2-one | 91069-39-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 8-ethyl-1-oxaspiro[4.5]-decan-2-one
• 英文别名: 1-Oxaspiro(4.5)decan-2-one, 8-ethyl-, cis-；8-ethyl-1-oxaspiro[4.5]decan-2-one
• CAS: 91069-39-5；91069-40-8
• 化学式: C₁₁H₁₈O₂
• 分子量: 182.263
• InChiKey: GITDWIBIPJFPDK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Organic Compounds
  申请人：Schilling Boris

  公开号：US20100113460A1

  公开（公告）日：2010-05-06

  Disclosed are compounds having the ability to inhibit cytochrome P450 2A6, 2A13, and/or 2B6 and tobacco products comprising them. Also disclosed are pharmaceutical compositions comprising them.

  揭示了一种具有抑制细胞色素P450 2A6、2A13和/或2B6能力的化合物，以及包含它们的烟草产品。还披露了包含这些化合物的药物组合物。
• Fragrance precursors
  申请人：——

  公开号：US20020035055A1

  公开（公告）日：2002-03-21

  The present invention provides a fragrance precursor of formula I: 1 that is capable of forming a fragrant ketone of formula II: 2 and a fragrant lactone of formula III: 3

  本发明提供了一种化学式I的香气前体：1，该前体能够形成化学式II的芳香酮：2和化学式III的芳香内酯：3。
• [EN] TRISUBSTITUTED FURANS SUITABLE FOR THE PREPARATION OF FRAGRANCE COMPOSITIONS<br/>[FR] FURANES TRISUBSTITUES CONVENANT A LA PREPARATION DE COMPOSITIONS DE PARFUM
  申请人：GIVAUDAN SA

  公开号：WO2005087756A1

  公开（公告）日：2005-09-22

  2,2-Disubstituted 5-methyl-2,5-dihydro- and 2,2-disubstituted 5-methyl-tetrahydrofurans of formula (I) wherein R1 and R2 have the same meaning as described in the specification are useful as odorants.

  式(I)中，R1和R2的含义如规范中所述的2,2-二取代的5-甲基-2,5-二氢呋喃和2,2-二取代的5-甲基四氢呋喃是有用的气味剂。
• Compounds having protected hydroxy groups
  申请人：Givaudan SA, a Switzerland corporation

  公开号：US20020193269A1

  公开（公告）日：2002-12-19

  The present invention relates to compounds with protected hydroxy groups of formula (I) 1 These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.

  本发明涉及具有保护羟基的化合物，其化学式为(I)1。这些化合物是有机感官剂（如香料）和掩蔽剂以及抗微生物剂的前体。当激活时，化学式(I)的化合物被裂解并形成一个或多个有机感官和/或抗微生物化合物。
• Trisubstituted Furans Suitable For The Preparation Of Fragrance Compositions
  申请人：Kraft Philip

  公开号：US20080039360A1

  公开（公告）日：2008-02-14

  2,2-Disubstituted 5-methyl-2,5-dihydro- and 2,2-disubstituted 5-methyl-tetrahydrofurans of formula (I) wherein R 1 and R 2 have the same meaning as described in the specification are useful as odorants.

  式(I)中R1和R2的含义如说明书所述的2,2-二取代的5-甲基-2,5-二氢呋喃和2,2-二取代的5-甲基四氢呋喃是有用的香气剂。