I+/--D-Mannopyranosyl chloride | 288399-11-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: I+/--D-Mannopyranosyl chloride
• 英文别名: 2-chloro-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 288399-11-1
• 化学式: C₆H₁₁ClO₅
• 分子量: 198.6
• InChiKey: JPYHXSWNADKGBI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.3
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  90.2
• 氢给体数：
  4
• 氢受体数：
  5

文献信息

• NOVEL GALACTOSIDE INHIBITOR OF GALECTINS
  申请人：Galecto Biotech AB

  公开号：EP3828191A2

  公开（公告）日：2021-06-02

  The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.

  本发明涉及通式（1）的化合物。 式（1）化合物适用于治疗哺乳动物（如人类）中与半凝集素（如半凝集素-3）与配体结合有关的紊乱的方法。此外，本发明还涉及一种治疗哺乳动物（如人类）中与半凝集素（如半凝集素-3）与配体结合有关的紊乱的方法。
• Galactoside inhibitor of galectins
  申请人：Galecto Biotech AB

  公开号：US10774102B2

  公开（公告）日：2020-09-15

  An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human.

  本发明的一个实施方案涉及通式化合物。通式化合物适用于治疗哺乳动物（如人类）中与半凝集素（如半凝集素-3）与配体结合有关的紊乱的方法。此外，本发明的一个实施方案涉及一种治疗哺乳动物（如人类）中与半凝集素（如半凝集素-3）与配体结合有关的紊乱的方法。
• Aminonaphthacene derivatives and their production
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0107486B1

  公开（公告）日：1987-04-29
• ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS
  申请人：Galecto Biotech AB

  公开号：EP3250581B1

  公开（公告）日：2021-01-20
• US4156720A
  申请人：——

  公开号：US4156720A

  公开（公告）日：1979-05-29