N-[[dimethyl-[(4-methylpyridin-2-yl)amino]silyl]oxy-dimethylsilyl]-4-methylpyridin-2-amine | 182245-12-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-[[dimethyl-[(4-methylpyridin-2-yl)amino]silyl]oxy-dimethylsilyl]-4-methylpyridin-2-amine
• CAS: 182245-12-1
• 化学式: C₁₆H₂₆N₄OSi₂
• 分子量: 346.58
• InChiKey: AUHDNHGVWMOEKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.04
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  59.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  (Me2N)3TiCl 、 N-[[dimethyl-[(4-methylpyridin-2-yl)amino]silyl]oxy-dimethylsilyl]-4-methylpyridin-2-amine 以 正己烷 为溶剂， 以88%的产率得到chlorotitanium(3+);dimethylazanide;[[dimethyl-(4-methylpyridin-2-yl)azanidylsilyl]oxy-dimethylsilyl]-(4-methylpyridin-2-yl)azanide;N-methylmethanamine
  参考文献：
  名称：

  Synthesis and Structure of Mononuclear Titanium Complexes Containing ansa ‐Aminopyridinato Ligands

  摘要：

  AbstractA series of siloxane‐bridged bis(2‐aminopyridines) were synthesized from dichlorosiloxanes and 2‐aminopyridines in the presence of a base via nucleophilic substitution reactions. They were used, after deprotonation, as dianionic (ansa‐aminopyridinato) ligands to stabilize mononuclear titanium complexes with unusual coordination geometries. An X‐ray crystal structure analysis of one of the ligands and of a titanium complex proved mononuclearity and provided information about the binding mode of this novel type of ligands. Ethylene polymerization studies showed low activity, remarkable differences between structurally related complexes, and broad molecular weight distributions. Sterically less demanding substituents and a high basicity of the ligand increase polymerization activity.

  DOI：

  10.1002/cber.19961290917
• 作为产物：
  描述：

  2-氨基-4-甲基吡啶 、 1,3-二氯-1,1,3,3,-四甲基二硅氧烷 在 三乙胺 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 以98%的产率得到N-[[dimethyl-[(4-methylpyridin-2-yl)amino]silyl]oxy-dimethylsilyl]-4-methylpyridin-2-amine
  参考文献：
  名称：

  Synthesis and Structure of Mononuclear Titanium Complexes Containing ansa ‐Aminopyridinato Ligands

  摘要：

  AbstractA series of siloxane‐bridged bis(2‐aminopyridines) were synthesized from dichlorosiloxanes and 2‐aminopyridines in the presence of a base via nucleophilic substitution reactions. They were used, after deprotonation, as dianionic (ansa‐aminopyridinato) ligands to stabilize mononuclear titanium complexes with unusual coordination geometries. An X‐ray crystal structure analysis of one of the ligands and of a titanium complex proved mononuclearity and provided information about the binding mode of this novel type of ligands. Ethylene polymerization studies showed low activity, remarkable differences between structurally related complexes, and broad molecular weight distributions. Sterically less demanding substituents and a high basicity of the ligand increase polymerization activity.

  DOI：

  10.1002/cber.19961290917

文献信息

• Complexes of Group 3 Metals and Lanthanides That Contain Siloxane-Bridged Bisaminopyridinato Ligands: Synthesis, Structure, and Application in the Ring-Opening Polymerization of Lactones
  作者：Henrik Noss、Markus Oberthür、Christine Fischer、Winfried P. Kretschmer、Rhett Kempe

  DOI：10.1002/(sici)1099-0682(199912)1999:12<2283::aid-ejic2283>3.0.co;2-t

  日期：1999.12

  give the corresponding "ate" complexes O(SiMe2-Ap)(2)Y(BH4)Cl(THF) Bu4N (5), O(SiMe2-Ap)(2)Y(BH4)(2)Na(THF)(2) (6) and O(SiMe2-Ap)(2)Y(CH(TMS)(2))(2)Li(THF)(3) (7), respectively. The steric demand of the O(SiMe2-Ap)(2-) ligand is not large enough to stabilize monoalkyl or monoborohydride complexes. Complex 4 has been used as an initiator for the ring-opening polymerization of epsilon-caprolactone or

  原位生成的一当量二锂化 O(SiMe2-Ap-H)(2) [Ap-H = -N(2-amino-4-methylpyridine)] (1) 与 LnCl(3) (Ln = Y, Sm) 在 THF 中得到 O(SiMe2-Ap)(2)YCl(THF)(2) (2) 或 O(SiMe2-Ap)(2)SmCl(THF)(3) (3)。相比之下，再次原位生成的一或两当量二锂化 1 与 THF 中的 LaBr3 反应得到 O(SiMe2-Ap)(2))(2)LaLi(THF)(3) (4)。2 和 3 的 X 射线结构分析显示 O(SiMe2-Ap)(2-) 配体以平面四齿方式结合。3 中的等效 Sm-N 距离表示离域结合模式。化合物 2 与 Bu4NBH4、NaBH4 或 LiCH(SiMe3)(2) 反应生成相应的“ate”配合物 O(SiMe2-Ap)(2)Y(BH4)Cl(THF) Bu4N
• Metal—-Metal “Communication” of Rh or Pd with Nd in Novel Heterobinuclear Complexes
  作者：Anke Spannenberg、Markus Oberthür、Henrik Noss、Annegret Tillack、Perdita Arndt、Rhett Kempe

  DOI：10.1002/(sici)1521-3773(19980817)37:15<2079::aid-anie2079>3.0.co;2-y

  日期：1998.8.17

  The reaction of a neodymium "ate" complex and an electron-rich transition metal chloride by salt elimination is an efficient method for synthesizing heterobinuclear compounds which contain a lanthanide and a Group 9 or 10 metal [Eq. (1), H2 Ap=2-amino-4-methylpyridine]. The use of bisaminopyridinato ligands allows extremely short distances between Rh or Pd and Nd.
• Synthesis and Structure of Mononuclear Titanium Complexes Containing <i>ansa</i> ‐Aminopyridinato Ligands
  作者：Markus Oberthür、Perdita Arndt、Rhett Kempe

  DOI：10.1002/cber.19961290917

  日期：1996.9

  AbstractA series of siloxane‐bridged bis(2‐aminopyridines) were synthesized from dichlorosiloxanes and 2‐aminopyridines in the presence of a base via nucleophilic substitution reactions. They were used, after deprotonation, as dianionic (ansa‐aminopyridinato) ligands to stabilize mononuclear titanium complexes with unusual coordination geometries. An X‐ray crystal structure analysis of one of the ligands and of a titanium complex proved mononuclearity and provided information about the binding mode of this novel type of ligands. Ethylene polymerization studies showed low activity, remarkable differences between structurally related complexes, and broad molecular weight distributions. Sterically less demanding substituents and a high basicity of the ligand increase polymerization activity.