[(4-Methylphenyl)-(2,4,6-trimethylphenyl)methyl] acetate | 807632-55-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [(4-Methylphenyl)-(2,4,6-trimethylphenyl)methyl] acetate
• 英文别名: [(4-methylphenyl)-(2,4,6-trimethylphenyl)methyl] acetate
• CAS: 807632-55-9
• 化学式: C₁₉H₂₂O₂
• 分子量: 282.382
• InChiKey: WAYKWQYXVHEEIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,5-二甲基呋喃 、 [(4-Methylphenyl)-(2,4,6-trimethylphenyl)methyl] acetate 在 三氯化铁 作用下， 以 二氯甲烷 为溶剂， 生成 3-(mesityl(p-tolyl)methyl)-2,5-dimethylfuran
  参考文献：
  名称：

  A simple access to triarylmethane derivatives from aromatic aldehydes and electron-rich arenes catalyzed by FeCl3

  摘要：

  Under 'open-flask' and mild conditions, arenes condense smoothly with aromatic aldehydes in the presence of catalytic amount of FeCl3. The reaction tolerated a variety of substitutions and functional groups. This method provides a facile and direct access to symmetrical and unsymmetrical triarylmethane derivatives. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.11.080
• 作为产物：
  描述：

  乙酸酐 、 对甲基苯甲醛 、 均三甲苯 在 三氯化铁 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 生成 [(4-Methylphenyl)-(2,4,6-trimethylphenyl)methyl] acetate
  参考文献：
  名称：

  A simple access to triarylmethane derivatives from aromatic aldehydes and electron-rich arenes catalyzed by FeCl3

  摘要：

  Under 'open-flask' and mild conditions, arenes condense smoothly with aromatic aldehydes in the presence of catalytic amount of FeCl3. The reaction tolerated a variety of substitutions and functional groups. This method provides a facile and direct access to symmetrical and unsymmetrical triarylmethane derivatives. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.11.080

文献信息

• An Efficient Iodine-Catalyzed Benzylation Reaction of 1,3-Dicarbonyl Compounds
  作者：Zheng Duan、Yangjie Wu、Zhongxian Li、Huaiqiu Wang、Rongqiang Tian、Qianrui Zhu

  DOI：10.1055/s-2008-1078216

  日期：——

  Under mild conditions, iodine promotes the direct alkylation of 1,3-dicarbonyl compounds with benzylic alcohols or benzylic acetates.

  在温和条件下，碘可促进 1,3-二羰基化合物与苯甲醇或乙酸苄酯的直接烷基化。
• A simple access to triarylmethane derivatives from aromatic aldehydes and electron-rich arenes catalyzed by FeCl3
  作者：Zhongxian Li、Zheng Duan、Jianxun Kang、Huaiqiu Wang、Liujian Yu、Yangjie Wu

  DOI：10.1016/j.tet.2007.11.080

  日期：2008.2

  Under 'open-flask' and mild conditions, arenes condense smoothly with aromatic aldehydes in the presence of catalytic amount of FeCl3. The reaction tolerated a variety of substitutions and functional groups. This method provides a facile and direct access to symmetrical and unsymmetrical triarylmethane derivatives. (C) 2007 Elsevier Ltd. All rights reserved.